JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Click Here for 5% Off Your First Aladdin Purchase!

྾

Home
Applications
Targets
Ligand-gated ion channels
Acid-sensing (proton-gated) ion channels (ASICs)
7-[(4-chlorophenyl)methyl-[2-(diethylamino)ethyl]amino]-2-oxochromene-3-carboximidamide , CAS No.C609322, Channel blocker of ASIC1

Skip to the end of the images gallery

Skip to the beginning of the images gallery

7-[(4-chlorophenyl)methyl-[2-(diethylamino)ethyl]amino]-2-oxochromene-3-carboximidamide , CAS No.C609322, Channel blocker of ASIC1

Moligand™

PubChem CID: 122177620

Item Number

C609322

Grouped product items
SKU	Size	Availability	Price	Qty
C609322-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
C609322-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

ASIC1 Channel blocker

Basic Description

Synonyms	compound 5b
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of ASIC1

Associated Targets

ASIC3 Tchem Acid-sensing ion channel 3 0 Activities

Discover Target: ASIC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC1 Tchem Acid-sensing ion channel 1 2 Activities

Discover Target: ASIC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC2 Tchem Acid-sensing ion channel 2 0 Activities

Discover Target: ASIC2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	7-[(4-chlorophenyl)methyl-[2-(diethylamino)ethyl]amino]-2-oxochromene-3-carboximidamide
INCHI	InChI=1S/C23H27ClN4O2/c1-3-27(4-2)11-12-28(15-16-5-8-18(24)9-6-16)19-10-7-17-13-20(22(25)26)23(29)30-21(17)14-19/h5-10,13-14H,3-4,11-12,15H2,1-2H3,(H3,25,26)
InChi Key	VVYLUODGYRRACW-UHFFFAOYSA-N
Canonical SMILES	CCN(CCN(c1ccc2c(c1)oc(=O)c(c2)C(=N)N)Cc1ccc(cc1)Cl)CC
Isomeric SMILES	CCN(CC)CCN(CC1=CC=C(C=C1)Cl)C2=CC3=C(C=C2)C=C(C(=O)O3)C(=N)N
PubChem CID	122177620

Database links

PubChem CID	122177620
ChEMBL Ligand	CHEMBL3577296
BindingDB Ligand	50096642

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

References

1. Buta A, Maximyuk O, Kovalskyy D, Sukach V, Vovk M, Ievglevskyi O, Isaeva E, Isaev D, Savotchenko A, Krishtal O. (2015) Novel Potent Orthosteric Antagonist of ASIC1a Prevents NMDAR-Dependent LTP Induction.. J Med Chem, 58 (11): (4449-61). [PMID:25974655]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.