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7-Amino-4-trifluoromethylcoumarin - 99%, high purity , CAS No.53518-15-3
Fluorescent marker. Substrate for fluorogenic enzyme assays.
Basic Description Synonyms 7-amino-4-(trifluoromethyl)-1-benzopyran-2-one | 7-Amino-4-(trifluoromethyl)-2-benzopyrone | BDBM83209 | HY-D0981 | A15632 | CCG-245871 | Coumarin 490 | SMR000034073 | 7-Amino-4-(trifluoromethyl)coumarin | 7-amino-4-trifluoromethylcumarin | 7-Amino-4-trif Specifications & Purity ≥99% Biochemical and Physiological Mechanisms Fluorescent marker. Substrate for fluorogenic enzyme assays. Calibration standard. Shipped In Normal Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. Product Description Product Application:
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488187215 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488187215 IUPAC Name 7-amino-4-(trifluoromethyl)chromen-2-one INCHI InChI=1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2 InChi Key JBNOVHJXQSHGRL-UHFFFAOYSA-N Canonical SMILES C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F Isomeric SMILES C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F WGK Germany 3 PubChem CID 100641 Molecular Weight 229.16 Beilstein 4456797
Chemical and Physical Properties Solubility Soluble in dimethyl sulfoxide (25 mg/ml), dimethyl formamide (25 mg/ml), and methanol (25 mg/ml). Insoluble in water. Melt Point(°C) 222-223°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3
Citations of This Product 1. Yi Sun, Wei Zhang, Shan Lu, Wenhua Miao, Meiling Chen, Fei Liu, Haining Na, Jin Zhu. (2023) Cellulose-based fluorescent materials fabricated in CO2 switchable solvent for freshness monitoring. CARBOHYDRATE POLYMERS, 301 (120346). [PMID:36446495 ] [10.1016/j.carbpol.2022.120346 ]
References 1. Yi Sun, Wei Zhang, Shan Lu, Wenhua Miao, Meiling Chen, Fei Liu, Haining Na, Jin Zhu. (2023) Cellulose-based fluorescent materials fabricated in CO2 switchable solvent for freshness monitoring. CARBOHYDRATE POLYMERS, 301 (120346). [PMID:36446495 ] [10.1016/j.carbpol.2022.120346 ]
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