7-BIA , CAS No.B607270, Inhibitor of RTP Type D;Inhibitor of RTP Type S

Item Number
B607270
Grouped product items
SKUSizeAvailabilityPrice Qty
B607270-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,340.90
B607270-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

Synonymscompound 14
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of RTP Type D;Inhibitor of RTP Type S

Associated Targets(Human)

PTPRD Tbio Receptor-type tyrosine-protein phosphatase delta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTPRS Tchem Receptor-type tyrosine-protein phosphatase S (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 7-butoxy-3-hydroxy-6-methoxy-1-oxo-3,4-dihydro-1H-2-benzopyran-5-carbaldehyde
INCHI InChI=1S/C15H18O6/c1-3-4-5-20-12-6-10-9(7-13(17)21-15(10)18)11(8-16)14(12)19-2/h6,8,13,17H,3-5,7H2,1-2H3
InChi Key DAVCIYWSVYDJKW-UHFFFAOYSA-N
Canonical SMILES CCCCOc1cc2C(=O)OC(Cc2c(c1OC)C=O)O
PubChem CID 137321149

Certificates

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References

1. Uhl GR, Martinez MJ, Paik P, Sulima A, Bi GH, Iyer MR, Gardner E, Rice KC, Xi ZX.  (2018)  Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist..  Proc Natl Acad Sci USA,  115  (45): (11597-11602).  [PMID:30348770] [10.1021/op500134e]

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