Inhibitor of receptor interacting serine/threonine kinase 1
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
1.Muendlein HI et al.. (2020) Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation.. Cell Rep, 30 (3):(699-713.e4). [PMID:31968247]
2.Wandel MP et al.. (2020) Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.. Nat Immunol, 21 (8):(880-891). [PMID:32541830]
3.Henning Y et al.. (2022) Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.. Cell Death Dis, 13 (7):(662). [PMID:35906211]
4.Yambire KF et al.. (2019) Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo.. Elife, 8 [PMID:31793879]
5.Egorshina AY et al.. (2022) Necroptosis as a Novel Facet of Mitotic Catastrophe.. Int J Mol Sci, 23 (7):[PMID:35409093]
6.Peek SL et al.. (2022) p53-mediated neurodegeneration in the absence of the nuclear protein Akirin2.. iScience, 25 (2):(103814). [PMID:35198879]
7.Kieckhöfer E et al.. (2022) Primary cilia suppress Ripk3-mediated necroptosis.. Cell Death Discov, 8 (477). [PMID:36460631]
8.Chen IT et al.. (2021) Promyelocytic leukemia protein targets MK2 to promote cytotoxicity.. EMBO Rep, 22 (12):(e52254). [PMID:34633746]
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