7-Deazaadenosine (Tubercidin) - ≥98%, high purity , CAS No.69-33-0

Item Number

D275970

• Synonyms: 7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | 7-Deazaadenosine | 7-deaza-adenosine | AKOS024464517 | MFCD00056012 | DB03172 | SR-01000765501 | U10071 | U-10071 | Q27089034 | 4-Amino-7-(beta-D-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine | Antib
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Adenosine analog antibiotic agent. Inhibits RNA processing, nucleic acid and protein synthesis. Shows antiproliferative (IC 50 = 2 nM, HEp-2 cells), antiviral (IC 50 = 30 nM, poliovirus), antiparasitic and antifungal effects.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

product description：

Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity.