7-(Diethylamino)coumarin-3-carboxylic Acid - >98.0%, high purity , CAS No.50995-74-9

2 Citations
  • ≥98%
Item Number
D154333
Grouped product items
SKUSizeAvailabilityPrice Qty
D154333-50mg
50mg
In stock
$9.90
D154333-250mg
250mg
In stock
$13.90
D154333-1g
1g
In stock
$32.90
D154333-5g
5g
In stock
$122.90

7-(Diethylamino)coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.

Basic Description

SynonymsMFCD00068721 | HY-D0067 | 7ACC1 | FT-0600960 | HMS560N21 | EN300-246176 | 7-(Diethylamino)coumarin-3-carboxylic acid | Coumarin D 1421 | D4238 | IDI1_006564 | 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylic acid | 7-diethylamino-2-oxo-2H-1-benzopyran-3-ca
Specifications & Purity≥98%
Biochemical and Physiological MechanismsDerivatisation reagent. Fluorescent label for amine modification and protein conjugation. Also used for labeling synthetic peptides for high-throughput detection.
Storage TempArgon charged
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

SLC16A3 Tchem Monocarboxylate transporter 4 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF-10A (2462 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SiHa (2051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-HEP1 (1155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
WiDr (1835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsomes (16955 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC16A3 Tchem Monocarboxylate transporter 4 (196 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KPNB1 Tbio Importin subunit beta-1/Snurportin-1 (25097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
4T1 (1737 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 7-(diethylamino)-2-oxochromene-3-carboxylic acid
INCHI InChI=1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
InChi Key WHCPTFFIERCDSB-UHFFFAOYSA-N
Canonical SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
Isomeric SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
PubChem CID 659294
Molecular Weight 261.28
Reaxy-Rn 6145963

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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7 results found

Lot NumberCertificate TypeDateItem
I1812150Certificate of AnalysisJul 14, 2022 D154333
I1812149Certificate of AnalysisJul 14, 2022 D154333
I2215371Certificate of AnalysisJul 03, 2022 D154333
C2218393Certificate of AnalysisDec 15, 2021 D154333
C2218397Certificate of AnalysisDec 15, 2021 D154333
F2326047Certificate of AnalysisDec 15, 2021 D154333
F2326052Certificate of AnalysisDec 15, 2021 D154333

Chemical and Physical Properties

SensitivityLight & Moisture Sensitive
Melt Point(°C)229 °C

Safety and Hazards(GHS)

Reaxy-Rn 6145963

Related Documents

Citations of This Product

1. Xiaokan Yu, Weisheng Zhu, Wenao Ouyang, Xiaojia Zhang, Hao Qiu, Zhijun Zhang, Bengang Xing.  (2022)  Protein-Mediated Fluorescence Resonance Energy Transfer (P-FRET) Probe: Fabrication and Hydroxyl Radical Detection†.  PHOTOCHEMISTRY AND PHOTOBIOLOGY,  98  (2): (371-377).  [PMID:35064566]
2. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu.  (2020-06-07)  Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid)..  Journal of hazardous materials,  398  (122854-122854).  [PMID:32504958]

References

1. Xiaokan Yu, Weisheng Zhu, Wenao Ouyang, Xiaojia Zhang, Hao Qiu, Zhijun Zhang, Bengang Xing.  (2022)  Protein-Mediated Fluorescence Resonance Energy Transfer (P-FRET) Probe: Fabrication and Hydroxyl Radical Detection†.  PHOTOCHEMISTRY AND PHOTOBIOLOGY,  98  (2): (371-377).  [PMID:35064566]
2. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu.  (2020-06-07)  Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid)..  Journal of hazardous materials,  398  (122854-122854).  [PMID:32504958]

Solution Calculators