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7-(Diethylamino)coumarin-3-carboxylic Acid - >98.0%, high purity , CAS No.50995-74-9
7-(Diethylamino)coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.
Basic Description Synonyms MFCD00068721 | HY-D0067 | 7ACC1 | FT-0600960 | HMS560N21 | EN300-246176 | 7-(Diethylamino)coumarin-3-carboxylic acid | Coumarin D 1421 | D4238 | IDI1_006564 | 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylic acid | 7-diethylamino-2-oxo-2H-1-benzopyran-3-ca Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Derivatisation reagent. Fluorescent label for amine modification and protein conjugation. Also used for labeling synthetic peptides for high-throughput detection. Storage Temp Argon charged Shipped In Normal Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 7-(diethylamino)-2-oxochromene-3-carboxylic acid INCHI InChI=1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17) InChi Key WHCPTFFIERCDSB-UHFFFAOYSA-N Canonical SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O Isomeric SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O PubChem CID 659294 Molecular Weight 261.28 Reaxy-Rn 6145963
Chemical and Physical Properties Sensitivity Light & Moisture Sensitive Melt Point(°C) 229 °C
Citations of This Product 1. Xiaokan Yu, Weisheng Zhu, Wenao Ouyang, Xiaojia Zhang, Hao Qiu, Zhijun Zhang, Bengang Xing. (2022) Protein-Mediated Fluorescence Resonance Energy Transfer (P-FRET) Probe: Fabrication and Hydroxyl Radical Detection†. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 98 (2): (371-377). [PMID:35064566 ] [10.1111/php.13595 ] 2. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu. (2020-06-07) Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid).. Journal of hazardous materials, 398 (122854-122854). [PMID:32504958 ]
References 1. Xiaokan Yu, Weisheng Zhu, Wenao Ouyang, Xiaojia Zhang, Hao Qiu, Zhijun Zhang, Bengang Xing. (2022) Protein-Mediated Fluorescence Resonance Energy Transfer (P-FRET) Probe: Fabrication and Hydroxyl Radical Detection†. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 98 (2): (371-377). [PMID:35064566 ] [10.1111/php.13595 ] 2. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu. (2020-06-07) Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid).. Journal of hazardous materials, 398 (122854-122854). [PMID:32504958 ]
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