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Orphan and other 7TM receptors
G protein-coupled receptors (GPCRs)
7α,25-dihydroxycholesterol - >98%, high purity , CAS No.64907-22-8, Agonist of GPR183

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7α,25-dihydroxycholesterol - >98%, high purity , CAS No.64907-22-8, Agonist of GPR183

≥98%

CAS#: 64907-22-8
Formula: C₂₇H₄₆O₃
Molecular Weight: 418.652
PubChem CID: 11954197

Item Number

D130221

Grouped product items
SKU	Size	Availability	Price	Qty
D130221-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$221.90

Highly potent GPR183 (EBI2) agonist

View related series

GPR183 Agonist

Basic Description

Synonyms	7alpha,25-Dihydroxycholesterol\|64907-22-8\|7alpha,25-OHC\|Cholest-5-ene-3beta,7alpha,25-triol\|7-alpha,25-Dihydroxycholesterol\|7alpha,25-Dihydroxyxcholesterol\|CHEMBL4788348\|7\|A,25-dihydroxycholesterol\|5-Cholesten-3beta,7alpha,25-triol\|3beta,7alpha,25-Trihydr
Specifications & Purity	>98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Action Type	AGONIST
Mechanism of action	Agonist of GPR183

Associated Targets

GPR183 Tchem G-protein coupled receptor 183 2 Activities

Discover Target: GPR183

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
INCHI	InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
InChi Key	BQMSKLCEWBSPPY-IKVTXIKFSA-N
Canonical SMILES	CC(CCCC(C)(C)O)C1CCC2C1(CCC3C2C(C=C4C3(CCC(C4)O)C)O)C
Isomeric SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C
WGK Germany	3
PubChem CID	11954197
Molecular Weight	418.652

Database links

CAS Registry No.	64907-22-8
PubChem CID	11954197
ChEBI	CHEBI:37623
RCSB PDB Ligand	KJX
GPCRdb Ligand	7α,25-dihydroxycholesterol

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 4.19, Max Conc. mM: 10 with gentle warming

Safety and Hazards(GHS)

WGK Germany	3

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