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8-Geranyloxypsoralen - 99%, high purity , CAS No.7437-55-0
Phenylpropanoids Coumarins
Basic Description
| Synonyms | MLS002472920 | 9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one | SCHEMBL4538668 | CHEBI:174547 | NCGC00142593-01 | NSC 7606 | MFCD00869738 | MS-25150 | PD125655 | (E)-9-((3,7-Dimethyl-2,6-octadienyl)oxy)-7H-furo(3,2-g)(1)benzopyran- |
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| Specifications & Purity | ≥99% |
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| Biochemical and Physiological Mechanisms | 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC 50 of 3.93 μM. |
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| Storage Temp | Protected from light,Store at -80°C |
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| Shipped In | Ice chest + Ice pads |
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| Product Description | 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC 50 of 3.93 μM Form:Solid IC50& Target:IC50: 3.93 μM (P450 3A4) |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 9-[(2E)-3,7-dimethylocta-2,6-dienoxy]furo[3,2-g]chromen-7-one |
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| INCHI | InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-19-17(10-12-23-19)13-16-7-8-18(22)25-20(16)21/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+ |
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| InChi Key | SOVNCTNQAWWYAQ-OQLLNIDSSA-N |
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| Canonical SMILES | CC(=CCCC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C)C |
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| Isomeric SMILES | CC(=CCC/C(=C/COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)/C)C |
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| PubChem CID | 5317564 |
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| Molecular Weight | 338.41 |
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Chemical and Physical Properties
| Solubility | DMSO : 100 mg/mL (295.51 mM; Need ultrasonic) |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H302:Harmful if swallowed H317:May cause an allergic skin reaction |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
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