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8-Geranyloxypsoralen - 99%, high purity , CAS No.7437-55-0

≥99%

CAS#: 7437-55-0
Formula: C₂₁H₂₂O₄
Molecular Weight: 338.41
PubChem CID: 5317564

Item Number

G648061

Grouped product items
SKU	Size	Availability	Price
G648061-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$191.90
G648061-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$403.90
G648061-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$686.90

Phenylpropanoids Coumarins

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Cytochrome P450 Metabolic Enzyme/Protease Phenylpropanoids Coumarins

Basic Description

Synonyms	8-geranyloxypsoralen\|7437-55-0\|Xanthotoxol geranyl ether\|8-Geranyloxy psoralen\|9-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one\|71612-25-4\|CHEMBL1412710\|9-[(2E)-3,7-dimethylocta-2,6-dienoxy]furo[3,2-g]chromen-7-one\|9-[(3,7-Dimethyl-2,6-
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC 50 of 3.93 μM.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC 50 of 3.93 μM Form:Solid IC50& Target:IC50: 3.93 μM (P450 3A4)

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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CBX1 Tbio Chromobox protein homolog 1 0 Activities

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PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor 0 Activities

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POLH Tchem DNA polymerase eta 0 Activities

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RUNX1 Tbio Runt-related transcription factor 1 0 Activities

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RORC Tchem Nuclear receptor ROR-gamma 0 Activities

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RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 0 Activities

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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

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PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 0 Activities

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities

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ALOX15 Tchem Arachidonate 15-lipoxygenase 0 Activities

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BACE1 Tchem Beta-secretase 1 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

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GNAS Tbio Protein ALEX 0 Activities

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ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

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Names and Identifiers

IUPAC Name	9-[(2E)-3,7-dimethylocta-2,6-dienoxy]furo[3,2-g]chromen-7-one
INCHI	InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-19-17(10-12-23-19)13-16-7-8-18(22)25-20(16)21/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
InChi Key	SOVNCTNQAWWYAQ-OQLLNIDSSA-N
Canonical SMILES	CC(=CCCC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C)C
Isomeric SMILES	CC(=CCC/C(=C/COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)/C)C
PubChem CID	5317564
Molecular Weight	338.41

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.

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