8-Hydroxy-5-nitroquinoline - 97%, high purity , CAS No.4008-48-4

  • ≥97%
Item Number
H107536
Grouped product items
SKUSizeAvailabilityPrice Qty
H107536-1g
1g
In stock
$64.90
H107536-5g
5g
In stock
$292.90
H107536-25g
25g
In stock
$1,316.90
H107536-100g
100g
In stock
$4,738.90

Basic Description

Synonyms5-Nitro-8-hydroxyquinoline | 8-Quinolinol, 5-nitro- | Nitroxolina | W-106391 | 5-Nitroquinolin-8-ol, 96% | HNQ | Nitroxolinum | DB01422 | Nitrohydroxyquinoline | 5-Nitro-quinolin-8-ol | 5-nitroquinolin-8-ol | NITROXOLINE [MART.] | NCGC00160664-03 | Nitrox
Specifications & Purity≥97%
Biochemical and Physiological Mechanisms8-Hydroxy-5-nitroquinoline is an effective anti-microbial and anti-cancer agent. It is an effective drug for the treatment of urinary tract infections due to gram negative bacilli.
Storage TempArgon charged
Shipped InNormal

Associated Targets(Human)

BRD4 Tchem Bromodomain-containing protein 4 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HSP90AA1 Tchem Heat shock protein HSP 90-alpha (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
METAP2 Tchem Methionine aminopeptidase 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
COMT Tclin Catechol O-methyltransferase (404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
METAP1 Tchem Methionine aminopeptidase 1 (614 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSB Tchem Cathepsin B (3822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
METAP2 Tchem Methionine aminopeptidase 2 (1512 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSP90AA1 Tchem Heat shock protein HSP 90-alpha (4115 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecium (13803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alpha trans-inducing protein (VP16) (945 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dnaB Replicative DNA helicase (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATP-dependent molecular chaperone HSP82 (2186 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
recA Protein RecA (2211 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSP90 (947 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Burkholderia pseudomallei (576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Burkholderia thailandensis (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488182572
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182572
IUPAC Name 5-nitroquinolin-8-ol
INCHI InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H
InChi Key RJIWZDNTCBHXAL-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
Isomeric SMILES C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
WGK Germany 3
RTECS VC8225000
PubChem CID 19910
Molecular Weight 190.16
Beilstein 21(5)3,297
Reaxy-Rn 166146

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I2405323Certificate of AnalysisJun 24, 2024 H107536
I2405324Certificate of AnalysisJun 24, 2024 H107536
G2319514Certificate of AnalysisJul 27, 2023 H107536
G2319513Certificate of AnalysisJul 26, 2023 H107536

Chemical and Physical Properties

Solubilityalcohol: very slightly soluble diethyl ether: very slightly soluble hydrochloric acid: freely soluble (hot)
Sensitivityair sensitive,light sensitive
Melt Point(°C)180°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

H311:Toxic in contact with skin

H331:Toxic if inhaled

H301+H311+H331:Toxic if swallowed, in contact with skin or if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P361+P364:Take off immediately all contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS VC8225000
Reaxy-Rn 166146
Merck Index 6655

Related Documents

Citations of This Product

1. Yi Sun, Junfeng Su, Amjad Ali, Tinglin Huang, Shuai Zhang, Yitian Min.  (2023)  Enhanced nitrate and cadmium removal performance at low carbon to nitrogen ratio through immobilized redox mediator granules and functional strains in a bioreactor.  CHEMOSPHERE,  312  (137255).  [PMID:36402354] [10.1016/j.chemosphere.2022.137255]
2. Yong Cheng, Feifei Sun, Qichun Feng, Qiang Zhao, Yinghua Zhou.  (2017)  In situ synthesis of AgNPs@Ag(I)-AMTD metal-organic gel composite and its catalytic properties.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  522  (43).  [PMID:] [10.1016/j.colsurfa.2017.02.040]

References

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2. J M Hernández Molina,J Llosá,A Ventosa.  (1991-07-01)  In vitro activity of nitroxoline against clinical isolates of Candida species..  Mycoses,  34  ((7-8)): (323-325).  [PMID:1803236]
3. P Bourlioux,D Karam,A Amgar,M Perdiz.  (1989-06-01)  [Relation of the chelating property of nitroxoline, the surface hydrophobicity and the inhibition of bacterial adherence]..  Pathologie-biologie,  37  ((5 Pt 2)): (600-604).  [PMID:2571967]
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7. A V Yatsenko,K A Paseshnichenko,V V Chernyshev,H Schenk.  (2002-01-10)  Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride..  Acta crystallographica. Section C, Crystal structure communications,  58  ((Pt 1)): (o19-o21).  [PMID:11781483]
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9. A Amgar,C Bonissol,B Stoiljkovic.  (1989-07-01)  Activity in vitro of urine samples from patients treated by nitroxoline against mycoplasmas..  Journal of chemotherapy (Florence, Italy),  ((4 Suppl)): (226-228).  [PMID:16312380]
10. Mohamed M Ghoneim,Hanaa S El-Desoky,Mohamed M Abdel-Galeil.  (2010-09-14)  Electrochemistry of the antibacterial and antifungal drug nitroxoline and its determination in bulk form, pharmaceutical formulation and human blood..  Bioelectrochemistry (Amsterdam, Netherlands),  80  ((2)): (162-168).  [PMID:20833114]
11. Joong Sup Shim,Yoshiyuki Matsui,Shridhar Bhat,Benjamin A Nacev,Jing Xu,Hyo-eun C Bhang,Surajit Dhara,Kee Chung Han,Curtis R Chong,Martin G Pomper,Alan So,Jun O Liu.  (2010-11-20)  Effect of nitroxoline on angiogenesis and growth of human bladder cancer..  Journal of the National Cancer Institute,  102  ((24)): (1855-1873).  [PMID:21088277]
12. Bojana Mirković,Miha Renko,Samo Turk,Izidor Sosič,Zala Jevnikar,Nataša Obermajer,Dušan Turk,Stanislav Gobec,Janko Kos.  (2011-05-21)  Novel mechanism of cathepsin\u2005B inhibition by antibiotic nitroxoline and related compounds..  ChemMedChem,  ((8)): (1351-1356).  [PMID:21598397]
13. Hongchao Jiang,Jori E Taggart,Xiaoxi Zhang,Doris M Benbrook,Stuart E Lind,Wei-Qun Ding.  (2011-09-09)  Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline)..  Cancer letters,  312  ((1)): (11-17).  [PMID:21899946]
14. Bojana Mirković,Izidor Sosič,Stanislav Gobec,Janko Kos.  (2011-11-11)  Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety..  PloS one,  ((11)): (e27197-e27197).  [PMID:22073285]
15. V Arjunan,P S Balamourougane,M Kalaivani,Arushma Raj,S Mohan.  (2012-06-26)  Experimental and theoretical quantum chemical investigations of 8-hydroxy-5-nitroquinoline..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  96  (506-516).  [PMID:22728969]
16. A Sobke,M Klinger,B Hermann,S Sachse,S Nietzsche,O Makarewicz,P M Keller,W Pfister,E Straube.  (2012-08-29)  The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc..  Antimicrobial agents and chemotherapy,  56  ((11)): (6021-6025).  [PMID:22926564]
17. Izidor Sosič,Bojana Mirković,Katharina Arenz,Bogdan Stefane,Janko Kos,Stanislav Gobec.  (2012-12-21)  Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives..  Journal of medicinal chemistry,  56  ((2)): (521-533).  [PMID:23252745]
18. Serena Veschi,Laura De Lellis,Rosalba Florio,Paola Lanuti,Alberto Massucci,Nicola Tinari,Michele De Tursi,Pierluigi di Sebastiano,Marco Marchisio,Clara Natoli,Alessandro Cama.  (2018-09-23)  Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells..  Journal of experimental & clinical cancer research : CR,  37  ((1)): (236-236).  [PMID:30241558]
19. Rungrot Cherdtrakulkiat, Ratana Lawung, Sunanta Nabu, Srisurang Tantimavanich, Nujarin Sinthupoom, Supaluk Prachayasittikul, Virapong Prachayasittikul,.  (2019-08-20)  Nitroxoline: a potent antimicrobial agent against multidrug resistant Enterobacteriaceae..  EXCLI journal,    ( 445-453 ).  [PMID:31423123]
20. Serena Veschi,Simone Carradori,Laura De Lellis,Rosalba Florio,Davide Brocco,Daniela Secci,Paolo Guglielmi,Mattia Spano,Anatoly P Sobolev,Alessandro Cama.  (2020-06-27)  Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents..  Journal of enzyme inhibition and medicinal chemistry,  35  ((1)): (1331-1344).  [PMID:32588672]
21. L Oliviero,M Perdiz,P Bourlioux.  (1990-05-01)  [Direct effect of nitroxoline in the inhibition of bacterial adherence to urinary catheters]..  Pathologie-biologie,  38  ((5)): (455-458).  [PMID:2195455]
22. P Bourlioux,H Botto,D Karam,A Amgar,M Camey.  (1989-05-01)  [Inhibition of bacterial adherence by nitroxoline on cellular adhesion and on urinary catheter surfaces]..  Pathologie-biologie,  37  ((5)): (451-454).  [PMID:2674871]
23. E Bergogne-Berezin,G Berthelot,C Muller-Serieys.  (1987-06-01)  [Present status of nitroxoline]..  Pathologie-biologie,  35  ((5 Pt 2)): (873-878).  [PMID:3309832]
24. B V Soloveĭ,T P Soloveĭ.  (1995-01-01)  [Intensive combined therapy of patients with urogenital tuberculosis]..  Problemy tuberkuleza,  (1)  ((1)): (30-32).  [PMID:7761376]
25. C Pelletier,P Prognon,P Bourlioux.  (1995-03-01)  Roles of divalent cations and pH in mechanism of action of nitroxoline against Escherichia coli strains..  Antimicrobial agents and chemotherapy,  39  ((3)): (707-713).  [PMID:7793877]
26. C Pelletier,P Prognon,H Latrache,L Villart,P Bourlioux.  (1994-05-01)  [Microbiological consequences of chelation of bivalent metal cations by nitroxoline]..  Pathologie-biologie,  42  ((5)): (406-411).  [PMID:7824304]
27. B Murugasu-Oei,T Dick.  (2001-12-12)  In vitro activity of the chelating agents nitroxoline and oxine against Mycobacterium bovis BCG..  International journal of antimicrobial agents,  18  ((6)): (579-582).  [PMID:11738349]
28. A I Sow,N Diop,C T Ndour,M Soumare,M Seydi,M F Cisse,A Samb.  (2003-12-12)  [Urinary tract infections in Dakar: etiologies, therapeutic basis]..  Dakar medical,  45  ((1)): (59-61).  [PMID:14666793]
29. Gau-Yi Gao,Shan-Yang Lin.  (2009-06-17)  Thermodynamic investigations of nitroxoline sublimation by simultaneous DSC-FTIR method and isothermal TG analysis..  Journal of pharmaceutical sciences,  99  ((1)): (255-261).  [PMID:19530075]
30. Shridhar Bhat,Joong Sup Shim,Feiran Zhang,Curtis Robert Chong,Jun O Liu.  (2012-03-07)  Substituted oxines inhibit endothelial cell proliferation and angiogenesis..  Organic & biomolecular chemistry,  10  ((15)): (2979-2992).  [PMID:22391578]
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32. Yi Sun, Junfeng Su, Amjad Ali, Tinglin Huang, Shuai Zhang, Yitian Min.  (2023)  Enhanced nitrate and cadmium removal performance at low carbon to nitrogen ratio through immobilized redox mediator granules and functional strains in a bioreactor.  CHEMOSPHERE,  312  (137255).  [PMID:36402354] [10.1016/j.chemosphere.2022.137255]
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Solution Calculators