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8-Hydroxyquinoline-5-carboxylic Acid - 10mM in DMSO, high purity , CAS No.5852-78-8(DMSO)

1 Citations
  • 10mM in DMSO
Item Number
H580286
Grouped product items
SKUSizeAvailabilityPrice Qty
H580286-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$63.90
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Histone demethylase inhibitor; cell permeable

Basic Description

Synonyms5852-78-8 | IOX1 | 8-Hydroxyquinoline-5-Carboxylic Acid | 8-Hydroxy-5-quinolinecarboxylic acid | 5-Carboxy-8-hydroxyquinoline | IOX 1 | IOX-1 | JM015YQC1C | CHEMBL1230640 | IOX1 compound | 8XQ | 5-carboxy-8HQ | 5-Quinolinecarboxylic acid, 8-hydroxy- | UNII-JM015YQC1C | 4bio | 4jht | 4ie
Specifications & PurityMoligand™, 10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

EGLN1 Tclin Egl nine homolog 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM4C Tchem Lysine-specific demethylase 4C (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM6B Tchem Lysine-specific demethylase 6B (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM3A Tchem Lysine-specific demethylase 3A (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM4E Tchem Lysine-specific demethylase 4E (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4D Tchem Lysine-specific demethylase 4D (224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4C Tchem Lysine-specific demethylase 4C (1129 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM3A Tchem Lysine-specific demethylase 3A (116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM2A Tchem Lysine-specific demethylase 2A (198 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM6B Tchem Lysine-specific demethylase 6B (280 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM6A Tchem Lysine-specific demethylase 6A (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5C Tchem Lysine-specific demethylase 5C (224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4B Tchem Lysine-specific demethylase 4B (165 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALKBH5 Tchem RNA demethylase ALKBH5 (134 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TET2 Tchem Methylcytosine dioxygenase TET2 (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A085R Prolyl 4-hydroxylase (72 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 8-hydroxyquinoline-5-carboxylic acid
INCHI InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
InChi Key JGRPKOGHYBAVMW-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O
Isomeric SMILES C1=CC2=C(C=CC(=C2N=C1)O)C(=O)O
WGK Germany 3
PubChem CID 459617
Molecular Weight 189.17

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 18.92, Max Conc. mM: 100; Solvent:1eq. NaOH, Max Conc. mg/mL: 18.92, Max Conc. mM: 100

Safety and Hazards(GHS)

Pictogram(s) GHS07
Hazard Statements

H302:Harmful if swallowed

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Guo Tongtong, Yang Shuang, Chen Yunning, Yang Lu, Sun Yingnan, Shang Qingkun.  (2021)  Photocatalytic kinetics and cyclic stability of photocatalysts Fe-complex/TiO2 in the synergistic degradation of phenolic pollutants and reduction of Cr(VI).  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  28  (10): (12459-12473).  [PMID:33079350] [10.1007/s11356-020-11220-1]

References

1. Guo Tongtong, Yang Shuang, Chen Yunning, Yang Lu, Sun Yingnan, Shang Qingkun.  (2021)  Photocatalytic kinetics and cyclic stability of photocatalysts Fe-complex/TiO2 in the synergistic degradation of phenolic pollutants and reduction of Cr(VI).  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  28  (10): (12459-12473).  [PMID:33079350] [10.1007/s11356-020-11220-1]

Solution Calculators

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