8-Hydroxyquinoline - 99%, high purity , CAS No.148-24-3

14 Citations
  • AR
  • ≥99%
Item Number
H104638
Grouped product items
SKUSizeAvailabilityPrice Qty
H104638-25g
25g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$10.90
H104638-100g
100g
In stock
$33.90
H104638-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$113.90

RNA synthesis inhibitor and ion chelator

Basic Description

SynonymsNSC 2039 | Oxine | o-Oxychinolin | o-Oxychinolin [German] | Oxine;8-Hydroxyquinoline;Quinophenol;8-Quinolinone | SCHEMBL37189 | 8-Hydroxyquinoline Oxine | NCIOpen2_004264 | NSC 615011 | Oxychinoline | 8-Chinolinol [Czech] | 8-HYDROXYQUINOLINE (IARC) | HSD
Specifications & PurityAR, ≥99%
Biochemical and Physiological MechanismsRNA synthesis inhibitor that acts as a fungicide against Trichophyton mentagrophytes, Myrothecium verrucaria, and Trichoderma viride. The antifungal mechanism of action is not clear but appears to be structurally related.RNA synthesis inhibitor. Displays
Storage TempProtected from light,Argon charged
Shipped InNormal
GradeAR
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

8-Hydroxyquinoline is a monoprotic bidentate chelating agent The reaction of 8-hydroxyquinoline with aluminium(III) results in Alq3, a common component of organic light-emitting diodes (OLED's). Variations in the substituents on the quinoline rings affect its luminescent properties. 8-Hydroxyquinoline is employed in precipitating and separating metals, the preparation of fungicides, and as a dye
Used as a lipophilic monoprotic bidentate chelating agent.

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Galc Galactocerebrosidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HD1 Histone deacetylase (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
npr Thermolysin (425 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus mutans (2687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nakaseomyces glabratus (9108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida tropicalis (8381 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella enterica (1497 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FM3A (1296 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P388 (20296 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ScN2a (522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacterial leucyl aminopeptidase (60 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
botA Botulinum neurotoxin type A (1303 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brain (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Fructose-bisphosphate aldolase (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Burkholderia thailandensis (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488179645
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179645
IUPAC Name quinolin-8-ol
INCHI InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
InChi Key MCJGNVYPOGVAJF-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C(=C1)O)N=CC=C2
Isomeric SMILES C1=CC2=C(C(=C1)O)N=CC=C2
WGK Germany 3
RTECS VC4200000
PubChem CID 1923
UN Number 2811
Packing Group I
Molecular Weight 145.16
Beilstein 114512

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

22 results found

Lot NumberCertificate TypeDateItem
D23231247Certificate of AnalysisMay 05, 2023 H104638
D23231268Certificate of AnalysisMay 05, 2023 H104638
D23231325Certificate of AnalysisMay 05, 2023 H104638
D2323140Certificate of AnalysisMay 05, 2023 H104638
D2323148Certificate of AnalysisMay 05, 2023 H104638
D2323154Certificate of AnalysisMay 05, 2023 H104638
H2409093Certificate of AnalysisMay 05, 2023 H104638
L2212407Certificate of AnalysisDec 17, 2022 H104638
L2212387Certificate of AnalysisDec 17, 2022 H104638
L2212385Certificate of AnalysisDec 17, 2022 H104638
L2212383Certificate of AnalysisDec 17, 2022 H104638
L2212357Certificate of AnalysisDec 17, 2022 H104638
L2212299Certificate of AnalysisDec 17, 2022 H104638
G2205253Certificate of AnalysisJul 09, 2022 H104638
G2205254Certificate of AnalysisJul 09, 2022 H104638
G2205260Certificate of AnalysisMar 04, 2022 H104638
B2226578Certificate of AnalysisMar 04, 2022 H104638
G2205252Certificate of AnalysisMar 04, 2022 H104638
B2226579Certificate of AnalysisMar 04, 2022 H104638
B2226588Certificate of AnalysisMar 04, 2022 H104638
J2113565Certificate of AnalysisOct 16, 2021 H104638
B2226593Certificate of AnalysisOct 16, 2021 H104638

Show more⌵

Chemical and Physical Properties

SolubilitySoluble in acetone, ethanol, chloroform, and benzene. Insoluble in water
SensitivityLight sensitive.Air sensitive
Boil Point(°C)266.6°C
Melt Point(°C)76°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS09,   GHS05,   GHS07
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H318:Causes serious eye damage

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H360D:May damage the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

WGK Germany 3
RTECS VC4200000
Class 6.1
Merck Index 4843

Related Documents

Citations of This Product

1. Chun-Ping Li, Wen-Yue Zhang, Li-Xin Gao, Da-Quan Zhang.  (2023)  A patching reinforcement strategy for hybrid surfactants as electrolyte additives with excellent performance in aluminum-air batteries.  JOURNAL OF POWER SOURCES,  584  (18): (233604).  [PMID:16179339]
2. Niannian Tang, Chengbo Qian, Chengwen Zhang, Yuyuan Yao.  (2023)  Isolation anchoring strategy for fabricating high-loading uniformly dispersed iron-based catalysts toward selective removal of phenolic compounds.  SEPARATION AND PURIFICATION TECHNOLOGY,  326  (124789).  [PMID:]
3. Runjia Liu, Dan Xu, Yan Liu, Liang Wu, Qiwen Yong, Zhi-Hui Xie.  (2023)  Enhanced corrosion protection for MAO coating on magnesium alloy by the synergism of LDH doping with deposition of 8HQ inhibitor film.  CERAMICS INTERNATIONAL,  49  (30039).  [PMID:]
4. Shangwang Le, Qian Jiang, Hongcheng Pan.  (2018)  Synthesis of a Crystal Violet-Cadmium Hydroxyquinoline Iodine Nanocomposite for the Photoelectrochemical Sensing of Ascorbic Acid.  International Journal of Electrochemical Science,  13  (8960).  [PMID:]
5. Hehe Bai, Wenjun Gong, Yating Pang, Chaoyang Shi, Zhigang Zhang, Lili Guo, Yafeng Li, Lili Guo, Wenming Wang, Hongfei Wang.  (2023)  Synthesis, cytotoxicity, and biomacromolecule binding: Three isomers of nitrosylruthenium complexes with bidentate bioactive molecules as co-ligands.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  243  (125009).  [PMID:37245757]
6. Rui Guo, Yue Ji, Jinnan Chen, Jin Ye, Baoxia Ni, Li Li, Yongtan Yang.  (2023)  Multicolor Visual Detection of Deoxynivalenol in Grain Based on Magnetic Immunoassay and Enzymatic Etching of Plasmonic Gold Nanobipyramids.  Toxins,  15  (6): (351).  [PMID:37368652]
7. Yunfei Hu, Xiangkang Cao, Xiaoze Ma, Jinglong Pan, Guangyi Cai, Xinxin Zhang, Zehua Dong.  (2023)  A bifunctional epoxy coating doped by cerium (III)-8-hydroxyquinoline: Early self-reporting and stimuli-responsive inhibition on corrosion of Al substrate.  PROGRESS IN ORGANIC COATINGS,  182  (107616).  [PMID:]
8. Yuan Zhenfeng, Li Zhe, Zhao Xiaoxue, Ding Zhenyu, Xia Mingyuan, Dong Xuyang, Ni Pengjuan, Lu Yizhong.  (2023)  BSA-stabilized silver nanoclusters for efficient photoresponsive colorimetric detection of chromium(VI).  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (8): (1477-1485).  [PMID:36680590]
9. Yafei Zhen, Tao Lin, Hanjiao Chen, Jing Hu, Xiandeng Hou.  (2022)  Vapor Generation of Rare-Earth Elements via Reaction with Tetrahydroborate: Chemical Identities and Mechanisms of Formation.  ANALYTICAL CHEMISTRY,  94  (44): (15176–15182).  [PMID:36301518]
10. Xin Wang, Jinshuang Hu, Boxuan Yao, Hua Wei, Caiyun Zhang, Jiarui Zhou, Jian Liu, Shenghong Yang.  (2023)  Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots.  CHEMICAL ENGINEERING JOURNAL,  451  (138524).  [PMID:]
11. Ma Liang, Xuan Xiaojing, Fan Minghui, Zhang Yumeng, Yuan Guozan, Huang Guozheng, Liu Zi.  (2022)  A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis.  APOPTOSIS,  27  (7): (577-589).  [PMID:35674852]
12. Xiang Gao, Yujie Lv, Hongfang Ma, Houyi Ma.  (2022)  Novel high-performance and long-life anti-corrosion coating with rust conversion and self-healing characteristics based on waste biomass derived carbon nanosheets.  PROGRESS IN ORGANIC COATINGS,  166  (106820).  [PMID:]
13. Shuai Wang, Li-Hong Deng, Yi-Fei Du, Xian-Liang Song.  (2022)  Graphene carbon black as catalyst support: The influences of iron phthalocyanine loading and carbon black additive amount on the power generation performance of direct glucose fuel cell.  FUEL,  315  (123227).  [PMID:]
14. Xiaoshan Huang,Mingxin Guan,Zhuliangzi Lu,Yiping Hang.  (2018-08-30)  Determination of Trace Antimony (III) in Water Samples with Single Drop Microextraction Using BPHA-[C4mim][PF6] System Followed by Graphite Furnace Atomic Absorption Spectrometry..  International journal of analytical chemistry,  2018  (8045324-8045324).  [PMID:30154850]

References

1. Chun-Ping Li, Wen-Yue Zhang, Li-Xin Gao, Da-Quan Zhang.  (2023)  A patching reinforcement strategy for hybrid surfactants as electrolyte additives with excellent performance in aluminum-air batteries.  JOURNAL OF POWER SOURCES,  584  (18): (233604).  [PMID:16179339]
2. Niannian Tang, Chengbo Qian, Chengwen Zhang, Yuyuan Yao.  (2023)  Isolation anchoring strategy for fabricating high-loading uniformly dispersed iron-based catalysts toward selective removal of phenolic compounds.  SEPARATION AND PURIFICATION TECHNOLOGY,  326  (124789).  [PMID:]
3. Runjia Liu, Dan Xu, Yan Liu, Liang Wu, Qiwen Yong, Zhi-Hui Xie.  (2023)  Enhanced corrosion protection for MAO coating on magnesium alloy by the synergism of LDH doping with deposition of 8HQ inhibitor film.  CERAMICS INTERNATIONAL,  49  (30039).  [PMID:]
4. Shangwang Le, Qian Jiang, Hongcheng Pan.  (2018)  Synthesis of a Crystal Violet-Cadmium Hydroxyquinoline Iodine Nanocomposite for the Photoelectrochemical Sensing of Ascorbic Acid.  International Journal of Electrochemical Science,  13  (8960).  [PMID:]
5. Hehe Bai, Wenjun Gong, Yating Pang, Chaoyang Shi, Zhigang Zhang, Lili Guo, Yafeng Li, Lili Guo, Wenming Wang, Hongfei Wang.  (2023)  Synthesis, cytotoxicity, and biomacromolecule binding: Three isomers of nitrosylruthenium complexes with bidentate bioactive molecules as co-ligands.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  243  (125009).  [PMID:37245757]
6. Rui Guo, Yue Ji, Jinnan Chen, Jin Ye, Baoxia Ni, Li Li, Yongtan Yang.  (2023)  Multicolor Visual Detection of Deoxynivalenol in Grain Based on Magnetic Immunoassay and Enzymatic Etching of Plasmonic Gold Nanobipyramids.  Toxins,  15  (6): (351).  [PMID:37368652]
7. Yunfei Hu, Xiangkang Cao, Xiaoze Ma, Jinglong Pan, Guangyi Cai, Xinxin Zhang, Zehua Dong.  (2023)  A bifunctional epoxy coating doped by cerium (III)-8-hydroxyquinoline: Early self-reporting and stimuli-responsive inhibition on corrosion of Al substrate.  PROGRESS IN ORGANIC COATINGS,  182  (107616).  [PMID:]
8. Yuan Zhenfeng, Li Zhe, Zhao Xiaoxue, Ding Zhenyu, Xia Mingyuan, Dong Xuyang, Ni Pengjuan, Lu Yizhong.  (2023)  BSA-stabilized silver nanoclusters for efficient photoresponsive colorimetric detection of chromium(VI).  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (8): (1477-1485).  [PMID:36680590]
9. Yafei Zhen, Tao Lin, Hanjiao Chen, Jing Hu, Xiandeng Hou.  (2022)  Vapor Generation of Rare-Earth Elements via Reaction with Tetrahydroborate: Chemical Identities and Mechanisms of Formation.  ANALYTICAL CHEMISTRY,  94  (44): (15176–15182).  [PMID:36301518]
10. Xin Wang, Jinshuang Hu, Boxuan Yao, Hua Wei, Caiyun Zhang, Jiarui Zhou, Jian Liu, Shenghong Yang.  (2023)  Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots.  CHEMICAL ENGINEERING JOURNAL,  451  (138524).  [PMID:]
11. Ma Liang, Xuan Xiaojing, Fan Minghui, Zhang Yumeng, Yuan Guozan, Huang Guozheng, Liu Zi.  (2022)  A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis.  APOPTOSIS,  27  (7): (577-589).  [PMID:35674852]
12. Xiang Gao, Yujie Lv, Hongfang Ma, Houyi Ma.  (2022)  Novel high-performance and long-life anti-corrosion coating with rust conversion and self-healing characteristics based on waste biomass derived carbon nanosheets.  PROGRESS IN ORGANIC COATINGS,  166  (106820).  [PMID:]
13. Shuai Wang, Li-Hong Deng, Yi-Fei Du, Xian-Liang Song.  (2022)  Graphene carbon black as catalyst support: The influences of iron phthalocyanine loading and carbon black additive amount on the power generation performance of direct glucose fuel cell.  FUEL,  315  (123227).  [PMID:]
14. Xiaoshan Huang,Mingxin Guan,Zhuliangzi Lu,Yiping Hang.  (2018-08-30)  Determination of Trace Antimony (III) in Water Samples with Single Drop Microextraction Using BPHA-[C4mim][PF6] System Followed by Graphite Furnace Atomic Absorption Spectrometry..  International journal of analytical chemistry,  2018  (8045324-8045324).  [PMID:30154850]

Solution Calculators