Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A101360-1g | 1g | In stock | $26.90 | |
A101360-5g | 5g | In stock | $73.90 | |
A101360-25g | 25g | In stock | $114.90 | |
A101360-50g | 50g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $131.90 | |
A101360-100g | 100g | In stock | $237.90 | |
A101360-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,066.90 |
Chloride transport inhibitor
Synonyms | CAS-723-62-6 | XGWFJBFNAQHLEF-UHFFFAOYSA- | anthracene-9-carboxylic acid | HMS3675L16 | Tox21_202942 | 7VK69492FV | (9-AC) | FT-0621619 | NCGC00024906-03 | KBioGR_001569 | Spectrum4_000875 | 9-Anthracenecarboxylic acid | A0690 | KBio3_002733 | DTXCID60293 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Cl-transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | CHANNEL BLOCKER |
Mechanism of action | Channel blocker of CaCC;Channel blocker of ClC-1 |
Product Description | application: 9-Anthracenecarboxylic acid can be used as a starting material to synthesize: 9-Cyanoanthracene by reacting with cyanohydrins in the presence of a palladium catalyst. 6-Chloro-8-(9-anthracenyl)-9H-purine by Ag/SiO2 catalyzed reaction one-pot reaction with 6-chloro-4,5-pyrimidinediamine. It can also be used as a cross-linking agent to functionalize organic second-order nonlinear optical materials to enhance poling efficiency and temporal stability. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488179675 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179675 |
IUPAC Name | anthracene-9-carboxylic acid |
INCHI | InChI=1S/C15H10O2/c16-15(17)14-12-7-3-1-5-10(12)9-11-6-2-4-8-13(11)14/h1-9H,(H,16,17) |
InChi Key | XGWFJBFNAQHLEF-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C=C3C=CC=CC3=C2C(=O)O |
Isomeric SMILES | C1=CC=C2C(=C1)C=C3C=CC=CC3=C2C(=O)O |
WGK Germany | 3 |
RTECS | CB8764000 |
PubChem CID | 2201 |
Molecular Weight | 222.24 |
Beilstein | 1875336 |
Reaxy-Rn | 1875336 |
ChEBI | CHEBI:34507 |
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CAS Registry No. | 723-62-6 |
PubChem CID | 2201 |
ChEMBL Ligand | CHEMBL1513985 |
PubChem SID | 488179675 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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I2406075 | Certificate of Analysis | Aug 23, 2024 | A101360 |
I2406074 | Certificate of Analysis | Aug 23, 2024 | A101360 |
I2406073 | Certificate of Analysis | Aug 23, 2024 | A101360 |
H2419326 | Certificate of Analysis | Aug 05, 2024 | A101360 |
D2303457 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303463 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303460 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303458 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303456 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303455 | Certificate of Analysis | Feb 17, 2023 | A101360 |
D2303444 | Certificate of Analysis | Feb 17, 2023 | A101360 |
G1813059 | Certificate of Analysis | May 10, 2022 | A101360 |
B2321246 | Certificate of Analysis | Mar 07, 2022 | A101360 |
C2226547 | Certificate of Analysis | Mar 07, 2022 | A101360 |
C2226546 | Certificate of Analysis | Mar 07, 2022 | A101360 |
C2226545 | Certificate of Analysis | Mar 07, 2022 | A101360 |
C2226544 | Certificate of Analysis | Mar 07, 2022 | A101360 |
Solubility | Solvent:ethanol, Max Conc. mg/mL: None, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 100 |
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Melt Point(°C) | 213-217 °C |
Pictogram(s) | GHS06, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | CB8764000 |
Reaxy-Rn | 1875336 |
1. Shida Luo, Yuting Zhang, Yanshen Zhu, Xiao-Juan Wang, Xia Ran, Yulu He, Yanmin Kuang, Zhen Chi, Lijun Guo. (2023) Size-Regulated Hole and Triplet Energy Transfer from CdSe Quantum Dots to Organic Acceptors for Enhancing Singlet Oxygen Generation. INORGANIC CHEMISTRY, 62 (46): (19087–19095). [PMID:37934916] [10.1021/acs.inorgchem.3c03134] |
2. Ren-Man Zhu, Zi-Xuan Chang, Wen-Jian Zhang, Chun-Yan Hong. (2023) Polymerization-Induced Self-Assembly with Assistance of Aromatic Interactions Facilitates the Formation of Polymeric Nanotubes. MACROMOLECULES, 56 (9): (3296–3303). [PMID:] [10.1021/acs.macromol.3c00302] |
3. Zhen Chi, Jia Xu, Shida Luo, Xia Ran, Xiaojuan Wang, Pingan Liu, Yulu He, Yanmin Kuang, Lijun Guo. (2023) Triplet generation at the CdTe quantum dot/anthracene interface mediated by hot and thermalized electron exchange for enhanced production of singlet oxygen. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25 (12): (8913-8920). [PMID:36916640] [10.1039/D3CP00021D] |
4. Yongqi Liu, Lei Wang, Jingtao Jiang, Xiangke Wang, Chenghao Dai, Gengsheng Weng. (2023) Fast Healing of Covalently Cross-Linked Polymeric Hydrogels by Interfacially Ignited Fast Gelation. MACROMOLECULES, 56 (1): (49–58). [PMID:] [10.1021/acs.macromol.2c02065] |
5. Kui Li, Miao Sun, Wei-De Zhang. (2018) Polycyclic aromatic compounds-modified graphitic carbon nitride for efficient visible-light-driven hydrogen evolution. CARBON, 134 (134). [PMID:] [10.1016/j.carbon.2018.03.089] |
6. Jie Gao, Caihong Wang, Hongliang Tan. (2017) Dual-emissive polystyrene@zeolitic imidazolate framework-8 composite for ratiometric detection of singlet oxygen. Journal of Materials Chemistry B, 5 (46): (9175-9182). [PMID:32264599] [10.1039/C7TB02684F] |
7. Yinhui Yi, Odoom Jibrael Kingsford, Mwenze Nkulu Fiston, Junjuan Qian, Zhenjiang Liu, Lirong Liu, Gangbing Zhu. (2017) Perylenetetracarboxylic acid noncovalently functionalizes carbon nanohorn nanohybrids for electrochemical sensing of 4,4′-diaminobiphenyl. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 801 (38). [PMID:] [10.1016/j.jelechem.2017.07.025] |
8. Liu Hongmei, Chang Hong, Lv Jia, Jiang Cong, Li Zhenxi, Wang Fei, Wang Hui, Wang Mingming, Liu Chongyi, Wang Xinyu, Shao Naimin, He Bingwei, Shen Wanwan, Zhang Qiang, Cheng Yiyun. (2016) Screening of efficient siRNA carriers in a library of surface-engineered dendrimers. Scientific Reports, 6 (1): (1-11). [PMID:27121799] [10.1038/srep25069] |
9. Chao Xu, Yong Chen, Heng-Yi Zhang, Yu Liu. (2016) Photo-induced secondary assembly of bis(terpyridyl)dibenzo-24-crown-8/Zn2+ supramolecular polymer. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 331 (240). [PMID:] [10.1016/j.jphotochem.2015.04.014] |
1. Yukari Takeda,Sang Don Koh,Kenton M Sanders,Sean M Ward. (2007-11-24) Differential expression of ionic conductances in interstitial cells of Cajal in the murine gastric antrum.. The Journal of physiology, 586 ((3)): (859-873). [PMID:18033817] |
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6. H A Azab,S A El-Korashy,Z M Anwar,B H M Hussein,G M Khairy. (2009-11-21) Synthesis and fluorescence properties of Eu-anthracene-9-carboxylic acid towards N-acetyl amino acids and nucleotides in different solvents.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75 ((1)): (21-27). [PMID:19926521] |
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14. Joost Groen,David W Deamer,Alexander Kros,Pascale Ehrenfreund. (2012-07-17) Polycyclic aromatic hydrocarbons as plausible prebiotic membrane components.. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 42 ((4)): (295-306). [PMID:22798228] |
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31. Gabriel Stölting,Martin Fischer,Christoph Fahlke. (2014-03-19) ClC-1 and ClC-2 form hetero-dimeric channels with novel protopore functions.. Pflugers Archiv : European journal of physiology, 466 ((12)): (2191-2204). [PMID:24638271] |
32. Jorge Baruch Pineda-Farias,Paulino Barragán-Iglesias,Emanuel Loeza-Alcocer,Jorge E Torres-López,Héctor Isaac Rocha-González,Francisca Pérez-Severiano,Rodolfo Delgado-Lezama,Vinicio Granados-Soto. (2015-07-02) Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats.. Molecular pain, 11 (41-41). [PMID:26130088] |
33. Shida Luo, Yuting Zhang, Yanshen Zhu, Xiao-Juan Wang, Xia Ran, Yulu He, Yanmin Kuang, Zhen Chi, Lijun Guo. (2023) Size-Regulated Hole and Triplet Energy Transfer from CdSe Quantum Dots to Organic Acceptors for Enhancing Singlet Oxygen Generation. INORGANIC CHEMISTRY, 62 (46): (19087–19095). [PMID:37934916] [10.1021/acs.inorgchem.3c03134] |
34. Ren-Man Zhu, Zi-Xuan Chang, Wen-Jian Zhang, Chun-Yan Hong. (2023) Polymerization-Induced Self-Assembly with Assistance of Aromatic Interactions Facilitates the Formation of Polymeric Nanotubes. MACROMOLECULES, 56 (9): (3296–3303). [PMID:] [10.1021/acs.macromol.3c00302] |
35. Zhen Chi, Jia Xu, Shida Luo, Xia Ran, Xiaojuan Wang, Pingan Liu, Yulu He, Yanmin Kuang, Lijun Guo. (2023) Triplet generation at the CdTe quantum dot/anthracene interface mediated by hot and thermalized electron exchange for enhanced production of singlet oxygen. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25 (12): (8913-8920). [PMID:36916640] [10.1039/D3CP00021D] |
36. Yongqi Liu, Lei Wang, Jingtao Jiang, Xiangke Wang, Chenghao Dai, Gengsheng Weng. (2023) Fast Healing of Covalently Cross-Linked Polymeric Hydrogels by Interfacially Ignited Fast Gelation. MACROMOLECULES, 56 (1): (49–58). [PMID:] [10.1021/acs.macromol.2c02065] |
37. Kui Li, Miao Sun, Wei-De Zhang. (2018) Polycyclic aromatic compounds-modified graphitic carbon nitride for efficient visible-light-driven hydrogen evolution. CARBON, 134 (134). [PMID:] [10.1016/j.carbon.2018.03.089] |
38. Jie Gao, Caihong Wang, Hongliang Tan. (2017) Dual-emissive polystyrene@zeolitic imidazolate framework-8 composite for ratiometric detection of singlet oxygen. Journal of Materials Chemistry B, 5 (46): (9175-9182). [PMID:32264599] [10.1039/C7TB02684F] |
39. Yinhui Yi, Odoom Jibrael Kingsford, Mwenze Nkulu Fiston, Junjuan Qian, Zhenjiang Liu, Lirong Liu, Gangbing Zhu. (2017) Perylenetetracarboxylic acid noncovalently functionalizes carbon nanohorn nanohybrids for electrochemical sensing of 4,4′-diaminobiphenyl. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 801 (38). [PMID:] [10.1016/j.jelechem.2017.07.025] |
40. Liu Hongmei, Chang Hong, Lv Jia, Jiang Cong, Li Zhenxi, Wang Fei, Wang Hui, Wang Mingming, Liu Chongyi, Wang Xinyu, Shao Naimin, He Bingwei, Shen Wanwan, Zhang Qiang, Cheng Yiyun. (2016) Screening of efficient siRNA carriers in a library of surface-engineered dendrimers. Scientific Reports, 6 (1): (1-11). [PMID:27121799] [10.1038/srep25069] |
41. Chao Xu, Yong Chen, Heng-Yi Zhang, Yu Liu. (2016) Photo-induced secondary assembly of bis(terpyridyl)dibenzo-24-crown-8/Zn2+ supramolecular polymer. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 331 (240). [PMID:] [10.1016/j.jphotochem.2015.04.014] |