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9-Anthroic acid - 98%, high purity , CAS No.723-62-6, Channel blocker of CaCC;Channel blocker of ClC-1

Moligand™
≥98%

CAS#: 723-62-6
Formula: C₁₅H₁₀O₂
Molecular Weight: 222.24
Beilstein Registry Number: 1875336
EC Number: 211-964-9
MDL number: MFCD00001257
PubChem CID: 2201
PubChem SID: 488179675

Item Number

A101360

Grouped product items
SKU	Size	Availability	Price
A101360-1g	1g	In stock	$26.90
A101360-5g	5g	In stock	$73.90
A101360-25g	25g	In stock	$114.90
A101360-50g	50g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$131.90
A101360-100g	100g	In stock	$237.90
A101360-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,066.90

Chloride transport inhibitor

View related series

anthracene CaCC Channel blocker Carboxylic acid C15+ CD Exciton Chirality Method ClC-1 Channel blocker VRAC Channel blocker

Basic Description

Synonyms	anthracene-9-carboxylic acid\|9-Anthracenecarboxylic acid\|723-62-6\|9-Anthroic acid\|ANCA\|9-Carboxyanthracene\|9-AC\|Anthracene-10-carboxylic acid\|MFCD00001257\|DTXSID7049427\|CHEBI:34507\|7VK69492FV\|NSC-151909\|A9C\|9-Anthracenecarboxylic Acid (purified by sublima
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Cl-transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.
Shipped In	Normal
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of CaCC;Channel blocker of ClC-1
Note	50g卖完停产，不再备货
Product Description	application： 9-Anthracenecarboxylic acid can be used as a starting material to synthesize: 9-Cyanoanthracene by reacting with cyanohydrins in the presence of a palladium catalyst. 6-Chloro-8-(9-anthracenyl)-9H-purine by Ag/SiO2 catalyzed reaction one-pot reaction with 6-chloro-4,5-pyrimidinediamine. It can also be used as a cross-linking agent to functionalize organic second-order nonlinear optical materials to enhance poling efficiency and temporal stability.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 1 Activities

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Discover Target: CYP2D6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Discover Target: CYP2C19

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Discover Target: CYP2C9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Discover Target: USP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Discover Target: HSD17B10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Discover Target: KMT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities

Discover Target: HPGD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CLCN1 Tbio Chloride channel protein 1 0 Activities

Discover Target: CLCN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLA Tclin Alpha-galactosidase A 0 Activities

Discover Target: GLA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ANO1 Tclin Anoctamin-1 0 Activities

Discover Target: ANO1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Discover Target: KDM4E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC16A7 Tchem Monocarboxylate transporter 2 0 Activities

Discover Target: SLC16A7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC16A1 Tchem Monocarboxylate transporter 1 0 Activities

Discover Target: SLC16A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488179675
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179675
IUPAC Name	anthracene-9-carboxylic acid
INCHI	InChI=1S/C15H10O2/c16-15(17)14-12-7-3-1-5-10(12)9-11-6-2-4-8-13(11)14/h1-9H,(H,16,17)
InChi Key	XGWFJBFNAQHLEF-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)C=C3C=CC=CC3=C2C(=O)O
Isomeric SMILES	C1=CC=C2C(=C1)C=C3C=CC=CC3=C2C(=O)O
WGK Germany	3
RTECS	CB8764000
PubChem CID	2201
Molecular Weight	222.24
Beilstein	1875336
Reaxy-Rn	1875336

Database links

ChEBI	CHEBI:34507
CAS Registry No.	723-62-6
PubChem CID	2201
ChEMBL Ligand	CHEMBL1513985
PubChem SID	488179675

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

17 results found

Lot Number	Certificate Type	Date	Item
I2406075	Certificate of Analysis	Aug 23, 2024	A101360
I2406074	Certificate of Analysis	Aug 23, 2024	A101360
I2406073	Certificate of Analysis	Aug 23, 2024	A101360
H2419326	Certificate of Analysis	Aug 05, 2024	A101360
D2303457	Certificate of Analysis	Feb 17, 2023	A101360
D2303463	Certificate of Analysis	Feb 17, 2023	A101360
D2303460	Certificate of Analysis	Feb 17, 2023	A101360
D2303458	Certificate of Analysis	Feb 17, 2023	A101360
D2303456	Certificate of Analysis	Feb 17, 2023	A101360
D2303455	Certificate of Analysis	Feb 17, 2023	A101360
D2303444	Certificate of Analysis	Feb 17, 2023	A101360
G1813059	Certificate of Analysis	May 10, 2022	A101360
B2321246	Certificate of Analysis	Mar 07, 2022	A101360
C2226547	Certificate of Analysis	Mar 07, 2022	A101360
C2226546	Certificate of Analysis	Mar 07, 2022	A101360
C2226545	Certificate of Analysis	Mar 07, 2022	A101360
C2226544	Certificate of Analysis	Mar 07, 2022	A101360

Chemical and Physical Properties

Solubility	Solvent:ethanol, Max Conc. mg/mL: None, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 100
Melt Point(°C)	213-217 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	CB8764000
Reaxy-Rn	1875336

References

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18. Joon-Chul Kim,Sun-Hee Woo. (2015-09-18) Shear stress induces a longitudinal Ca(2+) wave via autocrine activation of P2Y1 purinergic signalling in rat atrial myocytes.. The Journal of physiology, 593 ((23)): (5091-5109). [PMID:26377030]
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30. I V Kubasov,R S Arutiunian. (2013-01-09) [Investigation and analysis of chloride channels distribution over the surface and T-tubule membranes of frog skeletal muscle].. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98 ((9)): (1149-1158). [PMID:23293819]
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