9-cis-Retinoic Acid - ≥98% (HPLC), high purity , Retinoid receptor agonist, CAS No.5300-03-8, Retinoid receptor agonist

Item Number

C134191

• Synonyms: Isotretinoin Retinoic acid | Toctino | (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid | [3H]-9-cis-retinoic acid | [3H]9-cis-retinoic acid | 1UA8E65KDZ | LG100057 | LG-100057 | tretinoine (French) (EINECS) | (2E,
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: High affinity, endogenous retinoic acid receptor (RAR) agonist (IC 50 = 14 nM for RARα, RARβ and RARγ). Active metabolite of vitamin A. Acts as a transcription factor to regulate the growth and differentiation of normal and malignant cells
• Storage Temp: Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Retinoid receptor agonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.
A Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation