Click Here for 5% Off Your First Aladdin Purchase!

9-Phenanthrol - Technical Grade, high purity , CAS No.484-17-3, Channel blocker of TRPM4

  • Moligand™
  • technical grade
Item Number
P136335
Grouped product items
SKUSizeAvailabilityPrice Qty
P136335-250mg
250mg
In stock
$35.90
P136335-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$109.90
P136335-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$361.90

Selective TRPM4 blocker

View related series
TRPM4 Channel blocker

Basic Description

SynonymsPhenanthren-9-ol|9-PHENANTHROL|484-17-3|9-Hydroxyphenanthrene|9-Phenanthrenol|NSC 50554|CHEBI:28820|9FYU45OV9H|CHEMBL2407182|DTXSID9047592|9-Hydroxyphenanthrene; NSC 50554|MFCD00082298|NSC-50554|CCRIS 1840|EINECS 207-602-4|UNII-9FYU45OV9H|BRN 2047057|phen
Specifications & PurityMoligand™, technical grade
Biochemical and Physiological MechanismsSelective TRPM4 blocker (IC 50 = 20 μM). Modulates smooth muscle contraction. Reduces LPS-induced cell death. Promotes angiogenesis. Shows cardioprotective and anti-ischemic effects in vivo.
Shipped InNormal
GradeMoligand™, technical grade
Action TypeCHANNEL BLOCKER
Mechanism of actionChannel blocker of TRPM4
NoteNeed more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name phenanthren-9-ol
INCHI InChI=1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChi Key DZKIUEHLEXLYKM-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
Isomeric SMILES C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
WGK Germany 3
RTECS SF8288000
PubChem CID 10229
Molecular Weight 194.23

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
D1903146Certificate of AnalysisDec 08, 2022 P136335
A2226113Certificate of AnalysisFeb 08, 2022 P136335

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS SF8288000

Related Documents

References

1. Guinamard R, Hof T, Del Negro CA.  (2014)  The TRPM4 channel inhibitor 9-phenanthrol..  Br J Pharmacol,  171  (7): (1600-13).  [PMID:24433510]

Solution Calculators