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P424202-1ml

1ml

Available within 8-12 weeks(?)

$241.90

Basic Description

Synonyms	Phenanthren-9-ol \| 9-PHENANTHROL \| 484-17-3 \| 9-Hydroxyphenanthrene \| 9-Phenanthrenol \| NSC 50554 \| CHEBI:28820 \| 9FYU45OV9H \| CHEMBL2407182 \| DTXSID9047592 \| 9-Hydroxyphenanthrene; NSC 50554 \| MFCD00082298 \| NSC-50554 \| CCRIS 1840 \| EINECS 207-602-4 \| UNII-9FYU45OV9H \| BRN 2047057 \| phen
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Selective TRPM4 blocker (IC 50 = 20 μM). Modulates smooth muscle contraction. Reduces LPS-induced cell death. Promotes angiogenesis. Shows cardioprotective and anti-ischemic effects in vivo.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™

Associated Targets(Human)

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (0 Activities)

Discover Target: TRPM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HL-60 (67320 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (31 Activities)

Discover Target: TRPM4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	phenanthren-9-ol
INCHI	InChI=1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChi Key	DZKIUEHLEXLYKM-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
Isomeric SMILES	C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
WGK Germany	3
RTECS	SF8288000
PubChem CID	10229
Molecular Weight	194.23

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	SF8288000

Citations of This Product

1. Chun-Ying Xu, Yuan-Yuan Cui, Cheng-Xiong Yang. (2024) Fabrication of magnetic Fe3O4 doped β-cyclodextrin microporous organic network for the efficient extraction of endocrine disrupting chemicals from food takeaway boxes. JOURNAL OF CHROMATOGRAPHY A, 1715 (464625). [PMID:38171066]
2. Kai Hu, Tiantian Pang, Cheng Yang, Pengzhao Han, Lixin Li, Pan Wang, Zhenqiang Zhang, Wenjie Zhao, Shusheng Zhang. (2023) Simultaneous extraction of hydroxylated polycyclic aromatic hydrocarbons and catecholamines with magnetic boronic acid hypercrosslinked polymers. JOURNAL OF CHROMATOGRAPHY A, 1712 (464491). [PMID:37931428]
3. Zhengwen Wei, Yifan Du, Xiang-fei Lü, Wei Wang, Roberta Del Sole, Giuseppe Mele, Zhen-Yi Jiang. (2023) High-performance Fe3O4-terephthalaldehyde magnetic-nanocomposite for removal phenanthrene and 9-phenanthrol: A comprehensive experimental and theoretical analysis. SEPARATION AND PURIFICATION TECHNOLOGY, 306 (122610). [PMID:]
4. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang. (2023) Excellent removal performance of 4,4'-biphenyldicarboxaldehyde m-phenylenediamine Schiff base magnetic polymer towards phenanthrene and 9-phenanthrol: Experimental, modeling and DFT calculations studies. JOURNAL OF HAZARDOUS MATERIALS, 441 (129920). [PMID:36099739]
5. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang. (2022) Fe3O4-4,4′-biphenyldicarboxaldehyde superparamagnetic-nanomaterial for the high-efficiency removal of 9-phenanthrol: experimental combined with DFT investigations. Environmental Science-Nano, 9 (9): (3562-3580). [PMID:]
6. Sun Fei, Feng Chao, Wang Yang, Yang Xue, Zhao Hong. (2022) Preparation of fluorescent polystyrene microspheres by improving swelling performance based on molecular weight and surface carboxyl group content. QUIMICA NOVA, 45 (2): (145-151). [PMID:]
7. Cholho Choe, Ling Yang, Zhanao Lv, Wanling Mo, Zhuqi Chen, Guangxin Li, Guochuan Yin,. (2015-04-24) Redox-inactive metal ions promoted the catalytic reactivity of non-heme manganese complexes towards oxygen atom transfer.. Dalton transactions (Cambridge, England : 2003), 44 ((19)): ( 9182-9192 ). [PMID:25904197]

References

1. Chun-Ying Xu, Yuan-Yuan Cui, Cheng-Xiong Yang. (2024) Fabrication of magnetic Fe3O4 doped β-cyclodextrin microporous organic network for the efficient extraction of endocrine disrupting chemicals from food takeaway boxes. JOURNAL OF CHROMATOGRAPHY A, 1715 (464625). [PMID:38171066]
2. Kai Hu, Tiantian Pang, Cheng Yang, Pengzhao Han, Lixin Li, Pan Wang, Zhenqiang Zhang, Wenjie Zhao, Shusheng Zhang. (2023) Simultaneous extraction of hydroxylated polycyclic aromatic hydrocarbons and catecholamines with magnetic boronic acid hypercrosslinked polymers. JOURNAL OF CHROMATOGRAPHY A, 1712 (464491). [PMID:37931428]
3. Zhengwen Wei, Yifan Du, Xiang-fei Lü, Wei Wang, Roberta Del Sole, Giuseppe Mele, Zhen-Yi Jiang. (2023) High-performance Fe3O4-terephthalaldehyde magnetic-nanocomposite for removal phenanthrene and 9-phenanthrol: A comprehensive experimental and theoretical analysis. SEPARATION AND PURIFICATION TECHNOLOGY, 306 (122610). [PMID:]
4. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang. (2023) Excellent removal performance of 4,4'-biphenyldicarboxaldehyde m-phenylenediamine Schiff base magnetic polymer towards phenanthrene and 9-phenanthrol: Experimental, modeling and DFT calculations studies. JOURNAL OF HAZARDOUS MATERIALS, 441 (129920). [PMID:36099739]
5. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang. (2022) Fe3O4-4,4′-biphenyldicarboxaldehyde superparamagnetic-nanomaterial for the high-efficiency removal of 9-phenanthrol: experimental combined with DFT investigations. Environmental Science-Nano, 9 (9): (3562-3580). [PMID:]
6. Sun Fei, Feng Chao, Wang Yang, Yang Xue, Zhao Hong. (2022) Preparation of fluorescent polystyrene microspheres by improving swelling performance based on molecular weight and surface carboxyl group content. QUIMICA NOVA, 45 (2): (145-151). [PMID:]
7. Cholho Choe, Ling Yang, Zhanao Lv, Wanling Mo, Zhuqi Chen, Guangxin Li, Guochuan Yin,. (2015-04-24) Redox-inactive metal ions promoted the catalytic reactivity of non-heme manganese complexes towards oxygen atom transfer.. Dalton transactions (Cambridge, England : 2003), 44 ((19)): ( 9182-9192 ). [PMID:25904197]

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9-Phenanthrol - 10mM in DMSO, high purity , CAS No.484-17-3