A-1155463 - ≥97%, high purity , CAS No.1235034-55-5

Item Number

A276431

• Synonyms: A 1155463 | 2-(8-(Benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-(4-(3-(dimethylamino)prop-1-yn-1-yl)-2-fluorophenoxy)propyl)thiazole-4-carboxylic acid
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Highly potent, selective BCL-X L inhibitor. Shows picomolar binding affinity to BCL-X L (K i i =\xa080 nM)\xa0and related proteins BCL-W (K i = 19 nM) and MCL-1 (K i >440 nM).
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.