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A-412997 dihydrochloride - ≥98%, high purity , CAS No.630116-49-3, Agonist of D 4 receptor

  • Moligand™
  • ≥98%
Item Number
A274865
Grouped product items
SKUSizeAvailabilityPrice Qty
A274865-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
A274865-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
A274865-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$659.90
A274865-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,329.90
A274865-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,979.90

Highly selective D 4 agonist

View related series
D4 receptor Agonist

Basic Description

Synonyms630116-49-3|A-412997|A412997|N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide|RWL9H93ARB|CHEMBL375596|1-Piperidineacetamide, N-(3-methylphenyl)-4-(2-pyridinyl)-|a-412997 dihydrochloride|2-(4-(pyridin-2-yl)piperidin-1-yl)-N-m-tolylacetamide|N-(
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsHighly selective dopamine D 4 receptor agonist at rat D 4 and human D 4.4 receptors (K i values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D 4 receptors (EC 50 = 28.4 nM).
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of D 4 receptor

Associated Targets

DRD1 Tclin D(1A) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD4 Tchem D(4) dopamine receptor 8 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD5 Tchem D(1B) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide
INCHI InChI=1S/C19H23N3O/c1-15-5-4-6-17(13-15)21-19(23)14-22-11-8-16(9-12-22)18-7-2-3-10-20-18/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23)
InChi Key JFCDMGGMCUKHST-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=CC=C1)NC(=O)CN2CCC(CC2)C3=CC=CC=N3
Isomeric SMILES CC1=CC(=CC=C1)NC(=O)CN2CCC(CC2)C3=CC=CC=N3
Alternate CAS 1347744-96-0
PubChem CID 10425450
Molecular Weight 309.41

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Related Documents

Solution Calculators