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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A274865-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $139.90 | |
A274865-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $419.90 | |
A274865-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $659.90 | |
A274865-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,329.90 | |
A274865-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,979.90 |
Highly selective D 4 agonist
Synonyms | 630116-49-3|A-412997|A412997|N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide|RWL9H93ARB|CHEMBL375596|1-Piperidineacetamide, N-(3-methylphenyl)-4-(2-pyridinyl)-|a-412997 dihydrochloride|2-(4-(pyridin-2-yl)piperidin-1-yl)-N-m-tolylacetamide|N-( |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Highly selective dopamine D 4 receptor agonist at rat D 4 and human D 4.4 receptors (K i values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D 4 receptors (EC 50 = 28.4 nM). |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of D 4 receptor |
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IUPAC Name | N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide |
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INCHI | InChI=1S/C19H23N3O/c1-15-5-4-6-17(13-15)21-19(23)14-22-11-8-16(9-12-22)18-7-2-3-10-20-18/h2-7,10,13,16H,8-9,11-12,14H2,1H3,(H,21,23) |
InChi Key | JFCDMGGMCUKHST-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC(=CC=C1)NC(=O)CN2CCC(CC2)C3=CC=CC=N3 |
Isomeric SMILES | CC1=CC(=CC=C1)NC(=O)CN2CCC(CC2)C3=CC=CC=N3 |
Alternate CAS | 1347744-96-0 |
PubChem CID | 10425450 |
Molecular Weight | 309.41 |
Wikipedia | A-412,997 |
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CAS Registry No. | 630116-49-3 |
PubChem CID | 10425450 |
ChEMBL Ligand | CHEMBL375596 |
GPCRdb Ligand | A412997 |
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Solubility | Soluble in water to 100 mM |
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