Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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C431109-100g | 100g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $924.90 |
Synonyms | 3zst | 2zym | alpha-Cyclodextrin, purum, >=98.0% (HPLC) | Cyclohexaamylose carbonate | Ins-457 | alpha-Cyclodextrin, FG, produced by Wacker Chemie AG, Burghausen, Germany, Food, >=98% (on dry substance) | Tox21_111015 | CS-0013302 | NSC269470 | AKOS004905 |
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Specifications & Purity | ≥99%(HPLC), produced by Wacker Chemie AG, Burghausen, Germany |
Legal Information | Cavasol is a registered trademark of Wacker Chemie AG |
Product Description | General Description α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. It is mainly used as a stabilizer for emulsions such as mayonnaise, margarine or butter creams. Application α-Cyclodextrin can form host-guest inclusion complexes with a wide variety of organometallics, which can as be used as a template for silica nanocasting to synthesize nanodisperse inorganic-organic hybrid materials. α-CD can undergo cross-linking with poly(ethylene oxide)s to form injectable and bioabsorbable supramolecular hydrogels. |
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IUPAC Name | (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol |
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INCHI | InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1 |
InChi Key | HFHDHCJBZVLPGP-RWMJIURBSA-N |
Canonical SMILES | C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(O2)C(C7O)O)CO)CO)CO)CO)CO)O)O)O |
Isomeric SMILES | C([C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@H](O2)[C@@H]([C@H]7O)O)CO)CO)CO)CO)CO)O)O)O |
WGK Germany | 3 |
PubChem CID | 444913 |
Molecular Weight | 972.84 |
Beilstein | 79627 |
Enter Lot Number to search for COA:
Specific Rotation[α] | 149° (C=1,H2O) |
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Melt Point(°C) | 278°C |
Signal | Warning |
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Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
WGK Germany | 3 |
Merck Index | 2718 |
1. You Zhang, Wenzhong Ma, Jing Zhong, Zhou Zhou, Haicun Yang, Zheng Cao, Shuo Wang. (2024) Rapid shape recovery and remodeling by tuning the topology of polycaprolactone-based polymer networks. POLYMER, 292 (126641). [PMID:] |
2. Lin Wang, Fangkun Xiao, Haochen Ge, Yunbo Tong, Congjie Gao, Guiru Zhu. (2024) The fabrication of thin-film nanocomposite membrane for organic solvent forward osmosis via host-guest chemistry of α-cyclodextrin. DESALINATION, 574 (117247). [PMID:] |
3. Hengjun Zhou, Chenyu Liu, Simiao Yu, Farishta Shafiq, Weihong Qiao. (2024) Amphiphilic conjugates for solubilization of paclitaxel as efficient drug carriers based on hyaluronic acid and cyclodextrins. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 683 (133026). [PMID:] |
4. Si-Qi Nie, Yun-Yue Yuan, Hui-Min Zeng, Zhan-Guo Jiang, Cai-Hong Zhan. (2023) Homohelical Self-Assembly of Trimer of α-Cyclodextrin and Octamolybdate. INORGANIC CHEMISTRY, 62 (46): (19153–19158). [PMID:37934703] |
5. Cai-yun LIU, Lu-lu WU, Shu-yue FAN, Yong-sheng TAO, Yun-kui LI. (2023) The protective effect of cyclodextrin on color quality and stability of Cabernet Sauvignon red wine1. Journal of Integrative Agriculture, [PMID:16314522] |
6. Nan He, Chunxiao Zhang, Kaiyang Hou, Hongxiao Yu, Donghai Zhang, Mengying Chen, Kaiqiang Zhang, Xu Wang. (2023) A comprehensive study on flavor/cyclodextrin inclusion complexes. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 679 (11): (132613). [PMID:20084102] |
7. Qin Jiang, Miao Liu, Luo-Peng Xu, Zi-Ling Lu, Lei Zhang, Lu Zhang. (2023) Interfacial Rheological and Emulsion Properties of Self-Assembled Cyclodextrin–Oil Inclusion Complexes. LANGMUIR, 39 (33): (11675–11683). [PMID:37551025] |
8. Lulu Wang, Yuehai Peng, Wenfang Liu, Li Ren. (2023) Properties of Dual-Crosslinked Collagen-Based Membranes as Corneal Repair Material. Journal of Functional Biomaterials, 14 (7): (360). [PMID:37504855] |
9. Qin Zhang, Fang Guo, Run-Chi Zhao, Zhi-Hong Mo. (2023) Toward the green synthesis of CsPbBr3 perovskite nanocrystals using ethanol as an antisolvent and cyclodextrin as a ligand. NEW JOURNAL OF CHEMISTRY, 47 (20): (9771-9778). [PMID:] |
10. Wanjiao Chen, Weimin Wang, Chuan-Fan Ding, Fangling Wu, Yifeng Mai. (2023) Precise analysis of thyroxine enantiomers in pharmaceutical formulation by mobility difference based on cyclodextrin. Arabian Journal of Chemistry, 16 (104718). [PMID:] |
11. Tong Shao, Xiaolei Song, Yufeng Jiang, Chenchen Wang, Peng Li, Shihao Sun, Dingzhong Wang, Wei Wei. (2023) Vanillin-Catalyzed highly sensitive luminol chemiluminescence and its application in food detection. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 294 (122535). [PMID:36857865] |
12. Fuxing Xu, Shutong Yang, Fangling Wu, Chuan-Fan Ding. (2023) Chiral analysis of linear protonated dipeptides by complexing with Cyclodextrins using Ion-Mobility Mass-Spectrometry and DFT structural calculations. MICROCHEMICAL JOURNAL, 189 (108516). [PMID:] |
13. Liu Min, Wang Simin, Ge Wuxia, Bi Wentao, Chen David Da Yong. (2023) Influence of host–guest interactions on analytical performance of direct analysis in real-time mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4343-4352). [PMID:36651975] |
14. Boxuan Yao, Ke Zhang, Xiaoyang Liu, Hua Wei, Zihan Li, Jiarui Zhou, Guangfei Yuan, Xin Wang, Shenghong Yang, Jian Liu. (2023) Versatile preparation strategy of negatively charged saccharide-based polymers for selective removal of cationic organic pollutants. APPLIED SURFACE SCIENCE, 616 (156428). [PMID:] |
15. Yazhen Wu, Xiaoxiao Li, Zhengyu Jin, Birte Svensson, Yuxiang Bai. (2023) A practical approach to producing the single-arm linear dextrin, a chimeric glucosaccharide containing an (α-1 → 4) linked portion at the nonreducing end of an (α-1 → 6) glucochain. CARBOHYDRATE POLYMERS, 305 (120520). [PMID:36737184] |
16. Huanhuan Wang, Fangling Wu, Xinhua Dai, Xiang Fang, Chuan-Fan Ding. (2023) Rapid discrimination of enantiomers by ion mobility mass spectrometry and chemical theoretical calculation: Chiral mandelic acid and its derivatives. ANALYTICA CHIMICA ACTA, 1239 (340725). [PMID:36628725] |
17. Lei Jiang, Zeng Liu, Jia Liu, Shu He, Xing Wu, Wei Shao. (2023) Supramolecular lignin-containing hydrogel for flexible strain sensor via host-guest interaction and dynamic redox system. INDUSTRIAL CROPS AND PRODUCTS, 192 (116083). [PMID:] |
18. Xuqian Zhang, Ying He, Zitong Yuan, Guangmao Shen, Zan Zhang, Jinzhi Niu, Lin He, Jinjun Wang, Kun Qian. (2023) A pH- and enzymatic-responsive nanopesticide to control pea aphids and reduce toxicity for earthworms. SCIENCE OF THE TOTAL ENVIRONMENT, 861 (160610). [PMID:36460117] |
19. Fangling Wu, Xishi Wu, Zhe Li, Di Zhang, Chuan-Fan Ding. (2023) A cyclodextrin-based reagent for cis/trans-geometrical isomers separation by mobility measurements and chemical calculations. FOOD CHEMISTRY, 406 (135027). [PMID:36493573] |
20. Zhigang Liang, Huanhuan Wang, Fangling Wu, Longfei Wang, Chenwei Li, Chuan-Fan Ding. (2023) Drug adulteration analysis based on complexation with cyclodextrin and metal ions using ion mobility spectrometry. Journal of Pharmaceutical Analysis, 13 (287). [PMID:37102111] |
21. Guowei Li, Kai Lv, Xiangjun Pan, Siting Zhou, Hui Xing, Jun Xu, Dong Ma, Yunfeng Hu, Hao Xu. (2023) Dynamic nitric oxide/drug codelivery system based on polyrotaxane architecture for effective treatment of Candida albicans infection. Acta Biomaterialia, 155 (618). [PMID:36371005] |
22. Zhongbao Ma, Long-Fei Ren, Diwen Ying, Jinping Jia, Jiahui Shao. (2023) Dual-layer Janus charged nanofiltration membranes constructed by sequential electrospray polymerization for efficient water softening. CHEMOSPHERE, 310 (136929). [PMID:36273607] |
23. Xie Zhen-Hua, Huang Zi-Xin, Zhang Ze-Ping, Rong Min-Zhi, Zhang Ming-Qiu. (2023) Imparting Pulley Effect and Self-healability to Cathode Binder of Li-S Battery for Improvement of the Cycling Stability. CHINESE JOURNAL OF POLYMER SCIENCE, 41 (1): (95-107). [PMID:] |
24. Meixing Wang, Huizhen Hu, Buyu Zhang, Yang Zheng, Pan Wu, Zhenghui Lu, Guimin Zhang. (2022) Discovery of a New Microbial Origin Cold-Active Neopullulanase Capable for Effective Conversion of Pullulan to Panose. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (13): (6928). [PMID:35805929] |
25. Ruichun Du, Qi Jin, Tangsong Zhu, Changxian Wang, Sheng Li, Yanzhen Li, Xinxin Huang, Ying Jiang, Wenlong Li, Tianwei Bao, Pengfei Cao, Lijia Pan, Xiaodong Chen, Qiuhong Zhang, Xudong Jia. (2022) Sliding Cyclodextrin Molecules along Polymer Chains to Enhance the Stretchability of Conductive Composites. Small, 18 (19): (2200533). [PMID:35388964] |
26. Linqing Tian, Li Ha, Li Wang, Guangjin Chen, Frederic Coulon, Yuelu Jiang, Xin-Yang Zeng, Ruifeng Zhang, Guozhong Wu. (2022) Location optimization of silicon carbide foam packings in the unstirred packing trays reactor for the enhancement of solidified natural gas storage. CHEMICAL ENGINEERING SCIENCE, 253 (117503). [PMID:] |
27. Xiaoyu Lin, Qianyu Xu, Li Gan, Gary Owens, Zuliang Chen. (2022) Cyclodextrin modified green synthesized graphene oxide@iron nanoparticle composites for enhanced removal of oxytetracycline. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 608 (3159). [PMID:34823852] |
28. Xueyan Hu, Miaomiao Shang, Jing Wang, Ling Liu, Weibang Lu, Lin Ye, Jin Wang. (2021) Mass Formation of α-Cyclodextrin Hexagonal Rods by the Direct Solvent Evaporation Strategy. ACS Applied Bio Materials, 4 (11): (8033–8038). [PMID:35006784] |
29. Yunbo Li, Benguo Liu, Mengmeng Yu, Sheng Geng. (2021) High-efficiency formation mechanism of mangiferin/γ-cyclodextrin complex. FOOD SCIENCE AND TECHNOLOGY RESEARCH, [PMID:] |
30. Jianwei Du,Ce Tian,Yajie Liu,Jun Ling,Youxiang Wang. (2015-04-23) Azo-capped polysarcosine-b-polylysine as polypeptide gene vector: A new strategy to improve stability and easy optimization via host-guest interaction.. Colloids and surfaces. B, Biointerfaces, 130 (31-39). [PMID:25899841] |
31. Wei Ha,Ze-Hao Wang,Xiao-Bo Zhao,Yan-Ping Shi. (2020-10-13) Reinforced Supramolecular Hydrogels from Attapulgite and Cyclodextrin Pseudopolyrotaxane for Sustained Intra-Articular Drug Delivery.. Macromolecular bioscience, 21 ((1)): (e2000299-e2000299). [PMID:33043625] |
32. Xia Dong,Jie Liang,Afeng Yang,Zhiyong Qian,Deling Kong,Feng Lv. (2019-04-30) Fluorescence imaging guided CpG nanoparticles-loaded IR820-hydrogel for synergistic photothermal immunotherapy.. Biomaterials, 209 (111-125). [PMID:31034980] |
1. Hidetoshi Arima. (2004-07-06) [Polyfection as nonviral gene transfer method -design of novel nonviral vector using alpha-cyclodextrin].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 124 ((7)): (451-464). [PMID:15235229] |
2. Wei Ha,Min-min Fan,Sheng Zhang,Bang-jing Li. (2011-12-27) Self-assembly of chitosan-g-PEG and α-cyclodextrin into hollow spheres in aqueous solution.. Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1 (e204-e205). [PMID:22195855] |
3. Hiroyasu Yamaguchi,Yuichiro Kobayashi,Ryosuke Kobayashi,Yoshinori Takashima,Akihito Hashidzume,Akira Harada. (2012-01-05) Photoswitchable gel assembly based on molecular recognition.. Nature communications, 3 (603-603). [PMID:22215078] |
4. Juan Zhou,Jin Huang,Demei Tian,Haibing Li. (2012-01-10) Cyclodextrin modified quantum dots with tunable liquid-like behaviour.. Chemical communications (Cambridge, England), 48 ((30)): (3596-3598). [PMID:22222606] |
5. Takayuki Anno,Taishi Higashi,Keiichi Motoyama,Fumitoshi Hirayama,Kaneto Uekama,Hidetoshi Arima. (2012-02-07) Possible enhancing mechanisms for gene transfer activity of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate.. International journal of pharmaceutics, 426 ((1-2)): (239-247). [PMID:22306427] |
6. H Arima,M Arizono,T Higashi,A Yoshimatsu,H Ikeda,K Motoyama,K Hattori,T Takeuchi,F Hirayama,K Uekama. (2012-03-10) Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells.. Cancer gene therapy, 19 ((5)): (358-366). [PMID:22402627] |
7. Syed Mashhood Ali,Shania Khan,Gregory Crowyn. (2012-03-15) Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.. Magnetic resonance in chemistry : MRC, 50 ((4)): (299-304). [PMID:22416034] |
8. Yuya Hayashi,Yoshimasa Mori,Shogo Yamashita,Keiichi Motoyama,Taishi Higashi,Hirofumi Jono,Yukio Ando,Hidetoshi Arima. (2012-04-19) Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.. Molecular pharmaceutics, 9 ((6)): (1645-1653). [PMID:22510029] |
9. Yuya Hayashi,Yoshimasa Mori,Taishi Higashi,Keiichi Motoyama,Hirofumi Jono,Dinah W Y Sah,Yukio Ando,Hidetoshi Arima. (2012-04-24) Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 19 Suppl 1 (47-49). [PMID:22519861] |
10. M C Hamoudi,F Bourasset,V Domergue-Dupont,C Gueutin,V Nicolas,E Fattal,A Bochot. (2012-05-29) Formulations based on alpha cyclodextrin and soybean oil: an approach to modulate the oral release of lipophilic drugs.. Journal of controlled release : official journal of the Controlled Release Society, 161 ((3)): (861-867). [PMID:22634090] |
11. Sergey Shityakov,Jens Broscheit,Carola Förster. (2012-07-20) α-Cyclodextrin dimer complexes of dopamine and levodopa derivatives to assess drug delivery to the central nervous system: ADME and molecular docking studies.. International journal of nanomedicine, 7 (3211-3219). [PMID:22811606] |
12. Zhongshu Li,Erik P A Couzijn,Xiangyang Zhang. (2012-08-07) A quantitative study of intrinsic non-covalent interactions within complexes of α-cyclodextrin and benzoate derivatives.. Chemical communications (Cambridge, England), 48 ((79)): (9864-9866). [PMID:22864340] |
13. M C Hamoudi,J Saunier,C Gueutin,E Fattal,A Bochot. (2012-10-12) Beads made of α-cyclodextrin and soybean oil: the drying method influences bead properties and drug release.. Drug development and industrial pharmacy, 39 ((9)): (1306-1314). [PMID:23050693] |
14. Bárbara Herrera,Carolina Adura,Nicolás Yutronic,Marcelo J Kogan,Paul Jara. (2012-10-16) Selective nanodecoration of modified cyclodextrin crystals with gold nanorods.. Journal of colloid and interface science, 389 ((1)): (42-45). [PMID:23062962] |
15. Costanza Casati,Paola Franchi,Roberta Pievo,Elisabetta Mezzina,Marco Lucarini. (2012-10-31) Unraveling unidirectional threading of α-cyclodextrin in a [2]rotaxane through spin labeling approach.. Journal of the American Chemical Society, 134 ((46)): (19108-19117). [PMID:23106205] |
16. Tao Chen,JiaJun Fu. (2012-11-21) An intelligent anticorrosion coating based on pH-responsive supramolecular nanocontainers.. Nanotechnology, 23 ((50)): (505705-505705). [PMID:23165151] |
17. Juliana Isabel Clodt,Sofia Rangou,Anne Schröder,Kristian Buhr,Janina Hahn,Adina Jung,Volkan Filiz,Volker Abetz. (2012-12-12) Carbohydrates as additives for the formation of isoporous PS-b-P4VP diblock copolymer membranes.. Macromolecular rapid communications, 34 ((2)): (190-194). [PMID:23225180] |
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