α-Cyclodextrin - produced by Wacker Chemie AG, Burghausen, Germany, ≥99.0% (HPLC), high purity , CAS No.10016-20-3

32 Citations
  • ≥99%(HPLC)
  • produced by Wacker Chemie AG, Burghausen, Germany
Item Number
C431109
Grouped product items
SKUSizeAvailabilityPrice Qty
C431109-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$924.90

Basic Description

Synonyms3zst | 2zym | alpha-Cyclodextrin, purum, >=98.0% (HPLC) | Cyclohexaamylose carbonate | Ins-457 | alpha-Cyclodextrin, FG, produced by Wacker Chemie AG, Burghausen, Germany, Food, >=98% (on dry substance) | Tox21_111015 | CS-0013302 | NSC269470 | AKOS004905
Specifications & Purity≥99%(HPLC), produced by Wacker Chemie AG, Burghausen, Germany
Legal InformationCavasol is a registered trademark of Wacker Chemie AG
Product Description

General Description

α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. It is mainly used as a stabilizer for emulsions such as mayonnaise, margarine or butter creams.


Application

α-Cyclodextrin can form host-guest inclusion complexes with a wide variety of organometallics, which can as be used as a template for silica nanocasting to synthesize nanodisperse inorganic-organic hybrid materials. α-CD can undergo cross-linking with poly(ethylene oxide)s to form injectable and bioabsorbable supramolecular hydrogels.

Associated Targets(Human)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
INCHI InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1
InChi Key HFHDHCJBZVLPGP-RWMJIURBSA-N
Canonical SMILES C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(O2)C(C7O)O)CO)CO)CO)CO)CO)O)O)O
Isomeric SMILES C([C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@H](O2)[C@@H]([C@H]7O)O)CO)CO)CO)CO)CO)O)O)O
WGK Germany 3
PubChem CID 444913
Molecular Weight 972.84
Beilstein 79627

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]149° (C=1,H2O)
Melt Point(°C)278°C

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

WGK Germany 3
Merck Index 2718

Related Documents

Citations of This Product

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2. Lin Wang, Fangkun Xiao, Haochen Ge, Yunbo Tong, Congjie Gao, Guiru Zhu.  (2024)  The fabrication of thin-film nanocomposite membrane for organic solvent forward osmosis via host-guest chemistry of α-cyclodextrin.  DESALINATION,  574  (117247).  [PMID:]
3. Hengjun Zhou, Chenyu Liu, Simiao Yu, Farishta Shafiq, Weihong Qiao.  (2024)  Amphiphilic conjugates for solubilization of paclitaxel as efficient drug carriers based on hyaluronic acid and cyclodextrins.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  683  (133026).  [PMID:]
4. Si-Qi Nie, Yun-Yue Yuan, Hui-Min Zeng, Zhan-Guo Jiang, Cai-Hong Zhan.  (2023)  Homohelical Self-Assembly of Trimer of α-Cyclodextrin and Octamolybdate.  INORGANIC CHEMISTRY,  62  (46): (19153–19158).  [PMID:37934703]
5. Cai-yun LIU, Lu-lu WU, Shu-yue FAN, Yong-sheng TAO, Yun-kui LI.  (2023)  The protective effect of cyclodextrin on color quality and stability of Cabernet Sauvignon red wine1.  Journal of Integrative Agriculture,      [PMID:16314522]
6. Nan He, Chunxiao Zhang, Kaiyang Hou, Hongxiao Yu, Donghai Zhang, Mengying Chen, Kaiqiang Zhang, Xu Wang.  (2023)  A comprehensive study on flavor/cyclodextrin inclusion complexes.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  679  (11): (132613).  [PMID:20084102]
7. Qin Jiang, Miao Liu, Luo-Peng Xu, Zi-Ling Lu, Lei Zhang, Lu Zhang.  (2023)  Interfacial Rheological and Emulsion Properties of Self-Assembled Cyclodextrin–Oil Inclusion Complexes.  LANGMUIR,  39  (33): (11675–11683).  [PMID:37551025]
8. Lulu Wang, Yuehai Peng, Wenfang Liu, Li Ren.  (2023)  Properties of Dual-Crosslinked Collagen-Based Membranes as Corneal Repair Material.  Journal of Functional Biomaterials,  14  (7): (360).  [PMID:37504855]
9. Qin Zhang, Fang Guo, Run-Chi Zhao, Zhi-Hong Mo.  (2023)  Toward the green synthesis of CsPbBr3 perovskite nanocrystals using ethanol as an antisolvent and cyclodextrin as a ligand.  NEW JOURNAL OF CHEMISTRY,  47  (20): (9771-9778).  [PMID:]
10. Wanjiao Chen, Weimin Wang, Chuan-Fan Ding, Fangling Wu, Yifeng Mai.  (2023)  Precise analysis of thyroxine enantiomers in pharmaceutical formulation by mobility difference based on cyclodextrin.  Arabian Journal of Chemistry,  16  (104718).  [PMID:]
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12. Fuxing Xu, Shutong Yang, Fangling Wu, Chuan-Fan Ding.  (2023)  Chiral analysis of linear protonated dipeptides by complexing with Cyclodextrins using Ion-Mobility Mass-Spectrometry and DFT structural calculations.  MICROCHEMICAL JOURNAL,  189  (108516).  [PMID:]
13. Liu Min, Wang Simin, Ge Wuxia, Bi Wentao, Chen David Da Yong.  (2023)  Influence of host–guest interactions on analytical performance of direct analysis in real-time mass spectrometry.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (18): (4343-4352).  [PMID:36651975]
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15. Yazhen Wu, Xiaoxiao Li, Zhengyu Jin, Birte Svensson, Yuxiang Bai.  (2023)  A practical approach to producing the single-arm linear dextrin, a chimeric glucosaccharide containing an (α-1 → 4) linked portion at the nonreducing end of an (α-1 → 6) glucochain.  CARBOHYDRATE POLYMERS,  305  (120520).  [PMID:36737184]
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30. Jianwei Du,Ce Tian,Yajie Liu,Jun Ling,Youxiang Wang.  (2015-04-23)  Azo-capped polysarcosine-b-polylysine as polypeptide gene vector: A new strategy to improve stability and easy optimization via host-guest interaction..  Colloids and surfaces. B, Biointerfaces,  130  (31-39).  [PMID:25899841]
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References

1. Hidetoshi Arima.  (2004-07-06)  [Polyfection as nonviral gene transfer method -design of novel nonviral vector using alpha-cyclodextrin]..  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,  124  ((7)): (451-464).  [PMID:15235229]
2. Wei Ha,Min-min Fan,Sheng Zhang,Bang-jing Li.  (2011-12-27)  Self-assembly of chitosan-g-PEG and α-cyclodextrin into hollow spheres in aqueous solution..  Journal of controlled release : official journal of the Controlled Release Society,  152 Suppl 1  (e204-e205).  [PMID:22195855]
3. Hiroyasu Yamaguchi,Yuichiro Kobayashi,Ryosuke Kobayashi,Yoshinori Takashima,Akihito Hashidzume,Akira Harada.  (2012-01-05)  Photoswitchable gel assembly based on molecular recognition..  Nature communications,  (603-603).  [PMID:22215078]
4. Juan Zhou,Jin Huang,Demei Tian,Haibing Li.  (2012-01-10)  Cyclodextrin modified quantum dots with tunable liquid-like behaviour..  Chemical communications (Cambridge, England),  48  ((30)): (3596-3598).  [PMID:22222606]
5. Takayuki Anno,Taishi Higashi,Keiichi Motoyama,Fumitoshi Hirayama,Kaneto Uekama,Hidetoshi Arima.  (2012-02-07)  Possible enhancing mechanisms for gene transfer activity of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate..  International journal of pharmaceutics,  426  ((1-2)): (239-247).  [PMID:22306427]
6. H Arima,M Arizono,T Higashi,A Yoshimatsu,H Ikeda,K Motoyama,K Hattori,T Takeuchi,F Hirayama,K Uekama.  (2012-03-10)  Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells..  Cancer gene therapy,  19  ((5)): (358-366).  [PMID:22402627]
7. Syed Mashhood Ali,Shania Khan,Gregory Crowyn.  (2012-03-15)  Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies..  Magnetic resonance in chemistry : MRC,  50  ((4)): (299-304).  [PMID:22416034]
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Solution Calculators