A2B receptor antagonist 2 - 99%, high purity , CAS No.784-90-7

  • ≥99%
Item Number
A646135
Grouped product items
SKUSizeAvailabilityPrice Qty
A646135-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$50.90
A646135-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$75.90
A646135-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$117.90
View related series
Adenosine Receptor GPCR/G Protein

Basic Description

Synonyms784-90-7 | N-(4,6,7-trimethylquinazolin-2-yl)guanidine | 2-(4,6,7-trimethylquinazolin-2-yl)guanidine | A2B receptor antagonist 2 | GNF-Pf-1241 | 1-(4,6,7-trimethylquinazolin-2-yl)guanidine | CHEMBL528724 | Guanidine, (4,6,7-trimethyl-2-quinazolinyl)- | MLS000688740 | SCHEM
Specifications & Purity≥99%
Biochemical and Physiological MechanismsA2B receptor antagonist 2 (compound 18) is an adenosine receptor A 2B antagonist, with K i values of 2.30 μM, 6.8 μM and 3.44 μM for rA 1 , rA 2A and hA 2B , respectively.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

A2B receptor antagonist 2 (compound 18) is an adenosine receptor A 2B antagonist, with K i values of 2.30 μM, 6.8 μM and 3.44 μM for rA 1 , rA 2A and hA 2B , respectively.

Form:Solid

Associated Targets(Human)

Huh-7 (12904 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
QRFPR Tchem Pyroglutamylated RFamide peptide receptor (276 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CGA Tbio Glycoprotein hormones alpha chain (29278 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
WRN Tbio Werner syndrome ATP-dependent helicase (8824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAD52 Tchem DNA repair protein RAD52 homolog (856 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii (6656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
clpP ATP-dependent Clp protease proteolytic subunit (245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-(4,6,7-trimethylquinazolin-2-yl)guanidine
INCHI InChI=1S/C12H15N5/c1-6-4-9-8(3)15-12(17-11(13)14)16-10(9)5-7(6)2/h4-5H,1-3H3,(H4,13,14,15,16,17)
InChi Key JFQDHSRWWLJCBV-UHFFFAOYSA-N
Canonical SMILES CC1=CC2=C(N=C(N=C2C=C1C)N=C(N)N)C
Isomeric SMILES CC1=CC2=C(N=C(N=C2C=C1C)N=C(N)N)C
PubChem CID 2853458
Molecular Weight 229.29

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilityDMSO : 2 mg/mL (8.72 mM; ultrasonic and warming and heat to 60°C)

Related Documents

Solution Calculators