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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A275890-5mg | 5mg | In stock | $185.90 | |
A275890-25mg | 25mg | In stock | $693.90 | |
A275890-50mg | 50mg | In stock | $1,248.90 | |
A275890-100mg | 100mg | In stock | $2,246.90 |
Potent, selective and cell-permeable VEGFR inhibitor
Synonyms | 2-[(4-Pyridinylmethyl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Potent, selective and cell-permeable VEGFR inhibitor (IC 50 values are 130, 23 and 18 nM for VEGFR1, 2, and 3 respectively). Inhibits VEGF-induced angiogenesis in vivo. |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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IUPAC Name | 2-(pyridin-4-ylmethylamino)-N-[3-(trifluoromethyl)phenyl]benzamide |
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INCHI | InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) |
InChi Key | BLAFVGLBBOPRLP-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3 |
Isomeric SMILES | C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3 |
PubChem CID | 6398883 |
Molecular Weight | 371.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2229054 | Certificate of Analysis | Jun 08, 2023 | A275890 |
H2229055 | Certificate of Analysis | Jun 08, 2023 | A275890 |
H2229056 | Certificate of Analysis | Jun 08, 2023 | A275890 |
H2229057 | Certificate of Analysis | Jun 08, 2023 | A275890 |
Solubility | Soluble in ethanol to 25 mM and in DMSO to 50 mM |
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