Abacavir 5′-Phosphate , CAS No.136470-77-4

Item Number
A333304
Grouped product items
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A333304-1mg
1mg
Available within 8-12 weeks(?)
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$332.90

a nucleoside reverse transcriptase inhibitor (NRTI)

Basic Description

Synonymsabacavir 5'-phosphate | abacavir 5'-monophosphate | 136470-77-4 | abacavir phosphate | UNII-6I6AN9D95R | 6I6AN9D95R | abacavir monophosphate | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate | CHEBI:64112 | 2-Cyclopentene-
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Abacavir 5′-Phosphate is a metabolite of Abacavir which is a nucleoside reverse transcriptase inhibitor (NRTI). Abcavir [also called Ziagen ] is an HIV inhibitor, working by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme. The antiviral effect of abacavir is due to its intracellular anabolite, carbovir-triphosphate (CBV-TP).

Associated Targets(Human)

CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEL (6614 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADAL Tbio Adenosine deaminase-like protein (61 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis B virus (7925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Moloney murine sarcoma virus (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 2 (5592 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C3H/3T3 (186 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate
INCHI InChI=1S/C14H19N6O4P/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-24-25(21,22)23/h1,4,7-10H,2-3,5-6H2,(H2,21,22,23)(H3,15,17,18,19)/t8-,10+/m1/s1
InChi Key YQBOXVWMECPEJS-SCZZXKLOSA-N
Canonical SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)COP(=O)(O)O
Isomeric SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)COP(=O)(O)O
PubChem CID 469588
Molecular Weight 366.31

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