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Abacavir 5′-Phosphate , CAS No.136470-77-4
a nucleoside reverse transcriptase inhibitor (NRTI)
Basic Description Synonyms abacavir 5'-phosphate | abacavir 5'-monophosphate | 136470-77-4 | abacavir phosphate | UNII-6I6AN9D95R | 6I6AN9D95R | abacavir monophosphate | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate | CHEBI:64112 | 2-Cyclopentene- Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Abacavir 5′-Phosphate is a metabolite of Abacavir which is a nucleoside reverse transcriptase inhibitor (NRTI). Abcavir [also called Ziagen ] is an HIV inhibitor, working by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme. The antiviral effect of abacavir is due to its intracellular anabolite, carbovir-triphosphate (CBV-TP).
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate INCHI InChI=1S/C14H19N6O4P/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-24-25(21,22)23/h1,4,7-10H,2-3,5-6H2,(H2,21,22,23)(H3,15,17,18,19)/t8-,10+/m1/s1 InChi Key YQBOXVWMECPEJS-SCZZXKLOSA-N Canonical SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)COP(=O)(O)O Isomeric SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)COP(=O)(O)O PubChem CID 469588 Molecular Weight 366.31
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