Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
A129792-10mg | 10mg | In stock | $48.90 | |
A129792-50mg | 50mg | In stock | $122.90 | |
A129792-250mg | 250mg | In stock | $553.90 | |
A129792-1g | 1g | In stock | $1,992.90 | |
A129792-5g | 5g | In stock | $8,966.90 |
Potent, competitive guanosine analog reverse transcriptase inhibitor
Synonyms | Abacavir sulfate | Abacavir sulfate (JAN/USP) | B6091 | Abacavir sulfate racemic [USP-RS] | NSC-760063 | ABACAVIR SULFATE (MART.) | AS-17843 | DRG-0257 | Abacavir sulfate (USAN:USP) | ABACAVIR SULFATE [JAN] | ABACAVIR SULFATE [USP MONOGRAPH] | ABC sulfate |
---|---|
Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS;Abacavir sulfate is the sulfate form of abacavir, a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking HIV r |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | INHIBITOR |
Mechanism of action | Human immunodeficiency virus type 1 reverse transcriptase inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
Pubchem Sid | 488189783 |
---|---|
Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488189783 |
IUPAC Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid |
INCHI | InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1 |
InChi Key | WMHSRBZIJNQHKT-FFKFEZPRSA-N |
Canonical SMILES | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.OS(=O)(=O)O |
Isomeric SMILES | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.OS(=O)(=O)O |
WGK Germany | 3 |
PubChem CID | 441384 |
Molecular Weight | 335.35 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2329766 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329767 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329768 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329769 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329770 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329771 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329772 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329773 | Certificate of Analysis | Feb 24, 2023 | A129792 |
C2329774 | Certificate of Analysis | Feb 24, 2023 | A129792 |
E1520004 | Certificate of Analysis | Nov 11, 2022 | A129792 |
Solubility | Soluble in water (77 mg/ml), DMSO (< 1 mg/ml at 25 °C), ethanol (< 1 mg/ml at 25 °C), and methanol |
---|
Pictogram(s) | GHS08, GHS05 |
---|---|
Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H341:Suspected of causing genetic defects H351:Suspected of causing cancer H317:May cause an allergic skin reaction H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P281:Use personal protective equipment as required. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. |
WGK Germany | 3 |