Abacavir sulfate - ≥99%, high purity , Human immunodeficiency virus type 1 reverse transcriptase inhibitor, CAS No.188062-50-2, Human immunodeficiency virus type 1 reverse transcriptase inhibitor

  • ≥99%
Item Number
A129792
Grouped product items
SKUSizeAvailabilityPrice Qty
A129792-10mg
10mg
In stock
$48.90
A129792-50mg
50mg
In stock
$122.90
A129792-250mg
250mg
In stock
$553.90
A129792-1g
1g
In stock
$1,992.90
A129792-5g
5g
In stock
$8,966.90

Potent, competitive guanosine analog reverse transcriptase inhibitor

Basic Description

SynonymsAbacavir sulfate | Abacavir sulfate (JAN/USP) | B6091 | Abacavir sulfate racemic [USP-RS] | NSC-760063 | ABACAVIR SULFATE (MART.) | AS-17843 | DRG-0257 | Abacavir sulfate (USAN:USP) | ABACAVIR SULFATE [JAN] | ABACAVIR SULFATE [USP MONOGRAPH] | ABC sulfate
Specifications & Purity≥99%
Biochemical and Physiological MechanismsAbacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS;Abacavir sulfate is the sulfate form of abacavir, a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking HIV r
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionHuman immunodeficiency virus type 1 reverse transcriptase inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
A nucleoside reverse transcriptase inhibitor.

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488189783
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189783
IUPAC Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid
INCHI InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
InChi Key WMHSRBZIJNQHKT-FFKFEZPRSA-N
Canonical SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO.OS(=O)(=O)O
Isomeric SMILES C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO.OS(=O)(=O)O
WGK Germany 3
PubChem CID 441384
Molecular Weight 335.35

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
C2329766Certificate of AnalysisFeb 24, 2023 A129792
C2329767Certificate of AnalysisFeb 24, 2023 A129792
C2329768Certificate of AnalysisFeb 24, 2023 A129792
C2329769Certificate of AnalysisFeb 24, 2023 A129792
C2329770Certificate of AnalysisFeb 24, 2023 A129792
C2329771Certificate of AnalysisFeb 24, 2023 A129792
C2329772Certificate of AnalysisFeb 24, 2023 A129792
C2329773Certificate of AnalysisFeb 24, 2023 A129792
C2329774Certificate of AnalysisFeb 24, 2023 A129792
E1520004Certificate of AnalysisNov 11, 2022 A129792

Chemical and Physical Properties

SolubilitySoluble in water (77 mg/ml), DMSO (< 1 mg/ml at 25 °C), ethanol (< 1 mg/ml at 25 °C), and methanol

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS05
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H341:Suspected of causing genetic defects

H351:Suspected of causing cancer

H317:May cause an allergic skin reaction

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P281:Use personal protective equipment as required.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

WGK Germany 3

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