Skip to the beginning of the images gallery

ABC294640 - 98%, high purity , Sphingosine kinase 2 inhibitor, CAS No.915385-81-8, Sphingosine kinase 2 inhibitor

Moligand™

≥98%

CAS#: 915385-81-8
Formula: C₂₃H₂₅ClN₂O
Molecular Weight: 380.91
PubChem CID: 15604015

Item Number

A127517

Grouped product items
SKU	Size	Availability	Price
A127517-1mg	1mg	In stock	$43.90
A127517-5mg	5mg	In stock	$94.90
A127517-10mg	10mg	In stock	$165.90
A127517-25mg	25mg	In stock	$373.90
A127517-50mg	50mg	In stock	$521.90
A127517-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$878.90

View related series

sphingosine kinase 2 Inhibitor

Basic Description

Synonyms	ABC294640 \| Opaganib \| 915385-81-8 \| ABC-294640 \| 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide \| ABC 294640 \| CHEMBL2158685 \| Yeliva \| ABC294640Opaganib \| OPAGANIB [INN] \| OPAGANIB [WHO-DD] \| Opaganib (ABC294640) \| GTPL6624 \| SCHEMBL1548333 \| CHEBI:124965 \| DTXSID
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preven
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Sphingosine kinase 2 inhibitor

Associated Targets(Human)

SPHK2 Tchem Sphingosine kinase 2 (1 Activities)

Discover Target: SPHK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SPHK2 Tchem Sphingosine kinase 2 (1579 Activities)

Discover Target: SPHK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SPHK1 Tchem Sphingosine kinase 1 (1990 Activities)

Discover Target: SPHK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BXPC-3 (2997 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U-251 (51189 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DEGS1 Tchem Sphingolipid delta(4)-desaturase DES1 (28 Activities)

Discover Target: DEGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SPHK2 Tchem Sphingosine kinase 1/2 (28 Activities)

Discover Target: SPHK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Influenza A virus (11224 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide
INCHI	InChI=1S/C23H25ClN2O/c24-20-3-1-19(2-4-20)22-10-17-9-18(11-22)13-23(12-17,15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8,17-18H,9-15H2,(H,26,27)
InChi Key	CAOTVXGYTWCKQE-UHFFFAOYSA-N
Canonical SMILES	C1C2CC3(CC1CC(C2)(C3)C(=O)NCC4=CC=NC=C4)C5=CC=C(C=C5)Cl
Isomeric SMILES	C1C2CC3(CC1CC(C2)(C3)C(=O)NCC4=CC=NC=C4)C5=CC=C(C=C5)Cl
PubChem CID	15604015
Molecular Weight	380.91

PubChem CID

15604015

CAS Registry No.

915385-81-8

ChEMBL Ligand

CHEMBL2158685

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot Number	Certificate Type	Date	Item
A2207322	Certificate of Analysis	Oct 07, 2023	A127517
A2207323	Certificate of Analysis	Oct 07, 2023	A127517
A2207324	Certificate of Analysis	Oct 07, 2023	A127517
A2207325	Certificate of Analysis	Oct 07, 2023	A127517
A2207326	Certificate of Analysis	Oct 07, 2023	A127517
A2207327	Certificate of Analysis	Oct 07, 2023	A127517

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

ABC294640 - 98%, high purity , Sphingosine kinase 2 inhibitor, CAS No.915385-81-8, Sphingosine kinase 2 inhibitor

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator