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ABD-1970 , CAS No.2010154-82-0, Inhibitor of αβ-Hydrolase 6;Inhibitor of Monoacylglycerol lipase

  • Moligand™
  • ≥98%
Item Number
A607324
Grouped product items
SKUSizeAvailabilityPrice Qty
A607324-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
A607324-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$371.90
A607324-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,900.90
A607324-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,187.90
A607324-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,899.90

Basic Description

SynonymsABD1970
Specifications & PurityMoligand™, ≥98%
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of αβ-Hydrolase 6;Inhibitor of Monoacylglycerol lipase
Product Description

ABD-1970 is a highly potent and selective MGLL inhibitor.

Associated Targets

MGLL Tchem Monoglyceride lipase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLA2G7 Tchem Platelet-activating factor acetylhydrolase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[4-chloro-2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)phenyl]methyl]piperazine-1-carboxylate
INCHI InChI=1S/C21H24ClF6N3O3/c22-14-2-1-13(17(9-14)31-11-15-3-4-16(12-31)33-15)10-29-5-7-30(8-6-29)19(32)34-18(20(23,24)25)21(26,27)28/h1-2,9,15-16,18H,3-8,10-12H2
InChi Key CXSFVTMRWPSLGO-UHFFFAOYSA-N
Canonical SMILES C1CC2CN(CC1O2)C3=C(C=CC(=C3)Cl)CN4CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F
Isomeric SMILES C1CC2CN(CC1O2)C3=C(C=CC(=C3)Cl)CN4CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F
PubChem CID 122530045
Molecular Weight 515.88

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Clapper JR, Henry CL, Niphakis MJ, Knize AM, Coppola AR, Simon GM, Ngo N, Herbst RA, Herbst DM, Reed AW et al..  (2018)  Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators..  J Pharmacol Exp Ther,  367  (3): (494-508).  [PMID:30305428]

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