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ABT 639 - ≥98%(HPLC), high purity , Voltage-gated T-type calcium channel alpha-1H subunit blocker, CAS No.1235560-28-7, Voltage-gated T-type calcium channel alpha-1H subunit blocker

≥98%(HPLC)

CAS#: 1235560-28-7
Formula: C₂₀H₂₀ClF₂N₃O₃S
Molecular Weight: 455.91
PubChem CID: 46851313

Item Number

A287699

Grouped product items
SKU	Size	Availability	Price
A287699-5mg	5mg	In stock	$127.90
A287699-10mg	10mg	In stock	$216.90
A287699-25mg	25mg	In stock	$424.90
A287699-50mg	50mg	In stock	$682.90
A287699-100mg	100mg	In stock	$1,107.90

CaV3.2 and CaV3.1 channel blocker

View related series

Cav3.1 Channel blocker Cav3.2 Channel blocker Cav3.3 Channel blocker

Basic Description

Synonyms	ABT-639\|1235560-28-7\|ABT 639\|ABT-639 free base\|(R)-4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)benzenesulfonamide\|ABT639\|0G7D0CQ88I\|4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	CHANNEL BLOCKER
Mechanism of action	Voltage-gated T-type calcium channel alpha-1H subunit blocker

Associated Targets

CACNA1H Tclin Voltage-dependent T-type calcium channel subunit alpha-1H 1 Activities

Discover Target: CACNA1H

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1G Tclin Voltage-dependent T-type calcium channel subunit alpha-1G 1 Activities

Discover Target: CACNA1G

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1I Tclin Voltage-dependent T-type calcium channel subunit alpha-1I 1 Activities

Discover Target: CACNA1I

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	5-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-2-carbonyl]-4-chloro-2-fluoro-N-(2-fluorophenyl)benzenesulfonamide
INCHI	InChI=1S/C20H20ClF2N3O3S/c21-15-11-17(23)19(30(28,29)24-18-6-2-1-5-16(18)22)10-14(15)20(27)26-9-8-25-7-3-4-13(25)12-26/h1-2,5-6,10-11,13,24H,3-4,7-9,12H2/t13-/m1/s1
InChi Key	AGPIHNZOZNKRGT-CYBMUJFWSA-N
Canonical SMILES	C1CC2CN(CCN2C1)C(=O)C3=CC(=C(C=C3Cl)F)S(=O)(=O)NC4=CC=CC=C4F
Isomeric SMILES	C1C[C@@H]2CN(CCN2C1)C(=O)C3=CC(=C(C=C3Cl)F)S(=O)(=O)NC4=CC=CC=C4F
PubChem CID	46851313
Molecular Weight	455.91

PubChem CID

46851313

CAS Registry No.

1235560-28-7

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
C2226361	Certificate of Analysis	Feb 28, 2022	A287699
C2226362	Certificate of Analysis	Feb 28, 2022	A287699
C2226423	Certificate of Analysis	Feb 28, 2022	A287699
C2226437	Certificate of Analysis	Feb 28, 2022	A287699
C2226441	Certificate of Analysis	Feb 28, 2022	A287699

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