ABT 639 - ≥98%(HPLC), high purity , Voltage-gated T-type calcium channel alpha-1H subunit blocker, CAS No.1235560-28-7, Voltage-gated T-type calcium channel alpha-1H subunit blocker

  • ≥98%(HPLC)
Item Number
A287699
Grouped product items
SKUSizeAvailabilityPrice Qty
A287699-5mg
5mg
In stock
$127.90
A287699-10mg
10mg
In stock
$216.90
A287699-25mg
25mg
In stock
$424.90
A287699-50mg
50mg
In stock
$682.90
A287699-100mg
100mg
In stock
$1,107.90

CaV3.2 and CaV3.1 channel blocker

Basic Description

SynonymsAKOS030526344 | AGPIHNZOZNKRGT-CYBMUJFWSA-N | Benzenesulfonamide, 4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]- | HY-19721 | BDBM50095309 | ABT 639 | 4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahyd
Specifications & PurityMoligand™, ≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeCHANNEL BLOCKER
Mechanism of actionVoltage-gated T-type calcium channel alpha-1H subunit blocker

Product Properties

ALogP3.1

Associated Targets(Human)

CACNA1H Tclin Voltage-dependent T-type calcium channel subunit alpha-1H (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CACNA1G Tclin Voltage-dependent T-type calcium channel subunit alpha-1G (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CACNA1I Tclin Voltage-dependent T-type calcium channel subunit alpha-1I (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 5-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-2-carbonyl]-4-chloro-2-fluoro-N-(2-fluorophenyl)benzenesulfonamide
INCHI InChI=1S/C20H20ClF2N3O3S/c21-15-11-17(23)19(30(28,29)24-18-6-2-1-5-16(18)22)10-14(15)20(27)26-9-8-25-7-3-4-13(25)12-26/h1-2,5-6,10-11,13,24H,3-4,7-9,12H2/t13-/m1/s1
InChi Key AGPIHNZOZNKRGT-CYBMUJFWSA-N
Canonical SMILES C1CC2CN(CCN2C1)C(=O)C3=CC(=C(C=C3Cl)F)S(=O)(=O)NC4=CC=CC=C4F
Isomeric SMILES C1C[C@@H]2CN(CCN2C1)C(=O)C3=CC(=C(C=C3Cl)F)S(=O)(=O)NC4=CC=CC=C4F
PubChem CID 46851313
Molecular Weight 455.91

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
C2226361Certificate of AnalysisFeb 28, 2022 A287699
C2226362Certificate of AnalysisFeb 28, 2022 A287699
C2226423Certificate of AnalysisFeb 28, 2022 A287699
C2226437Certificate of AnalysisFeb 28, 2022 A287699
C2226441Certificate of AnalysisFeb 28, 2022 A287699

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 9.12, Max Conc. mM: 20

Related Documents

Solution Calculators