ABT-751 (E7010) - ≥98%, high purity , Tubulin beta inhibitor, CAS No.141430-65-1, Tubulin beta inhibitor

Item Number

A125698

• Synonyms: DTXSID60869913 | N-[2-(4-Hydroxy-phenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide | CCG-264843 | CHEBI:95043 | E-7010 | HMS3672M11 | NCGC00346494-03 | ABT751 | ABT-751 | BDBM50101086 | HMS3654C14 | N-(2-((4-Hydroxyphenyl)amino)-3-pyridinyl)-4-metho
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.Antimitotic agent. Microtubule polymerization inhibitor. Induces G
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Action Type: INHIBITOR
• Mechanism of action: Tubulin beta inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

ABT-751 is an orally bioavailable vascular disrupting agaent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on beta-tubulin and inhibits polymerization of microtubules.
An inhibitor of microtubule polymerization