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AC 261066 - ≥98%(HPLC), high purity , CAS No.870773-76-5, Agonist of Retinoic acid receptor-β
Basic Description Synonyms 870773-76-5 | AC-261066 | AC 261066 | AC261066 | LGF3F89BZP | 4-(4-(2-butoxyethoxy)-5-methylthiazol-2-yl)-2-fluorobenzoic acid | 4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid | Benzoic acid, 4-(4-(2-butoxyethoxy)-5-methyl-2-thiazolyl)-2-fluoro- | CHEM Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Potent RARβ2 agonist (pEC50= 8.1). Selective over RARβ1, RARαand RARγ(pEC50values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649. Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of Retinoic acid receptor-β
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 4-[4-(2-butoxyethoxy)-5-methyl-1,3-thiazol-2-yl]-2-fluorobenzoic acid INCHI InChI=1S/C17H20FNO4S/c1-3-4-7-22-8-9-23-15-11(2)24-16(19-15)12-5-6-13(17(20)21)14(18)10-12/h5-6,10H,3-4,7-9H2,1-2H3,(H,20,21) InChi Key HSAOETBFVAWNRP-UHFFFAOYSA-N Canonical SMILES CCCCOCCOC1=C(SC(=N1)C2=CC(=C(C=C2)C(=O)O)F)C Isomeric SMILES CCCCOCCOC1=C(SC(=N1)C2=CC(=C(C=C2)C(=O)O)F)C PubChem CID 11530459 Molecular Weight 353.41
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 35.34, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 35.34, Max Conc. mM: 100
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