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AC 5216 - ≥98%(HPLC), high purity , Translocator protein agonist, CAS No.226954-04-7, Translocator protein agonist

Moligand™

≥98%(HPLC)

CAS#: 226954-04-7
Formula: C₂₃H₂₃N₅O₂
Molecular Weight: 401.46
PubChem CID: 6433109

Item Number

A286555

Grouped product items
SKU	Size	Availability	Price
A286555-5mg	5mg	In stock	$112.90
A286555-10mg	10mg	In stock	$172.90
A286555-25mg	25mg	In stock	$389.90
A286555-50mg	50mg	In stock	$728.90
A286555-100mg	100mg	In stock	$1,311.90

Selective TSPO ligand

View related series

Translocator protein Agonist

Basic Description

Synonyms	OG837L732J \| BDBM50266889 \| Emapunil (AC 5216) \| Emapunil(AC-5216) \| N-Benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)ethanamide \| N-benzyl-N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-acetamide \| DTXSID30995036 \| Emapunil [INN] \| S
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki= 0.297 nM), and high potency against human and rat glial TSPO (IC50values are 2.73 and 3.04 nM respectively). Displays no not
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Translocator protein agonist

Associated Targets(Human)

TSPO Tchem Putative peripheral benzodiazepine receptor-related protein (1 Activities)

Discover Target: TSPO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSPO Tchem Translocator protein (3 Activities)

Discover Target: TSPO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSPO Tchem Translocator protein (484 Activities)

Discover Target: TSPO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK-293T (167025 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Tspo Peripheral-type benzodiazepine receptor (243 Activities)

Discover Target: Tspo

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)acetamide
INCHI	InChI=1S/C23H23N5O2/c1-3-27(15-17-10-6-4-7-11-17)20(29)16-28-22-19(26(2)23(28)30)14-24-21(25-22)18-12-8-5-9-13-18/h4-14H,3,15-16H2,1-2H3
InChi Key	NBMBIEOUVBHEBM-UHFFFAOYSA-N
Canonical SMILES	CCN(CC1=CC=CC=C1)C(=O)CN2C3=NC(=NC=C3N(C2=O)C)C4=CC=CC=C4
Isomeric SMILES	CCN(CC1=CC=CC=C1)C(=O)CN2C3=NC(=NC=C3N(C2=O)C)C4=CC=CC=C4
PubChem CID	6433109
Molecular Weight	401.46

PubChem CID

ChEMBL Ligand

CAS Registry No.

Wikipedia

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
K2229071	Certificate of Analysis	Oct 09, 2022	A286555
K2229096	Certificate of Analysis	Oct 09, 2022	A286555
K2229097	Certificate of Analysis	Oct 09, 2022	A286555
K2229102	Certificate of Analysis	Oct 09, 2022	A286555
K2229103	Certificate of Analysis	Oct 09, 2022	A286555

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AC 5216 - ≥98%(HPLC), high purity , Translocator protein agonist, CAS No.226954-04-7, Translocator protein agonist

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

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