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Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al - >97%, high purity , CAS No.169332-60-9, Inhibitor of Caspase 3
Basic Description Synonyms C20H30N4O11 | acetyl-Asp-Glu-Val-Asp aldehyde | N-acetyl-asp-glu-val-asp-al | s7901 | L-valinamide, N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]- | DTXSID40937624 | acetyl-Asp-Glu-Val-Asp-aldehyde | HY-P1001 | L-Valinamide, Specifications & Purity Moligand™, ≥97% Biochemical and Physiological Mechanisms N-ACETYL-ASP-GLU-VAL-ASP-AL (Ac-DEVD-CHO) may contribute to the recovery of stunned myocardium through its Cystatin function. Reversible inhibitor of IL-1 β; Invertase (Ice) ; inhibition of Poly (ADP-ribose) polymerase cleavage by CASPASE 3. Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of Caspase 3
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid INCHI InChI=1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)/t11-,12-,13-,17-/m0/s1 InChi Key UMBVAPCONCILTL-MRHIQRDNSA-N Canonical SMILES CC(C)C(C(=O)NC(CC(=O)O)C=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C Isomeric SMILES CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)C PubChem CID 644345 Molecular Weight 502.47
Chemical and Physical Properties Sensitivity Moisture sensitive
Citations of This Product 1. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233 ] [10.1016/j.jconrel.2022.11.026 ] 2. Kuo Yong, Sidra Kaleem, Mingzhu Ma, Xiaoyuan Lian, Zhizhen Zhang. (2022) Antiglioma Natural Products from the Marine-Associated Fungus Penicillium sp. ZZ1750. MOLECULES, 27 (20): (7099). [PMID:36296693 ] [10.3390/molecules27207099 ]
References 1. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233 ] [10.1016/j.jconrel.2022.11.026 ] 2. Kuo Yong, Sidra Kaleem, Mingzhu Ma, Xiaoyuan Lian, Zhizhen Zhang. (2022) Antiglioma Natural Products from the Marine-Associated Fungus Penicillium sp. ZZ1750. MOLECULES, 27 (20): (7099). [PMID:36296693 ] [10.3390/molecules27207099 ]
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G2205049