Basic Description

Synonyms	acarbose \| 56180-94-0 \| Glucobay \| Precose \| Bay g 5421 \| Prandase \| CHEBI:2376 \| BAY-g 5421 \| 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-D-glucopyranose \| SMR0004663
Specifications & Purity	Moligand™, 10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Maltase-glucoamylase inhibitor
Product Description	Acarbose, also known as BAY g 5421, is an α-glucosidase inhibitor that prevents absorption of sucrose and maltose. This compound has been found to delay digestion of complex disaccharides and carbohydrates. Further studies suggest that this compound can stimulate phosphorylase kinase (PhK) by binding to the glucoamylase-like domain new the amino termini and causing an alteration in the structure. An α-glucosidase inhibitor application： A reversible alpha-glucosidase inhibitorAcarbose is used as a reversible alfa-glucosidase inhibitor. It acts as an anti-diabetic drug, which finds useful application to treat type 2 diabetes mellitus and prediabetes. It is also employed for Hepatitis. It also acts as a beta glucosidase inhibitor, antihyperlipidaemia and antiobesity

Associated Targets(Human)

AMY2A Tclin Pancreatic alpha-amylase (0 Activities)

Discover Target: AMY2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol
INCHI	InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
InChi Key	XUFXOAAUWZOOIT-UGEKTDRHSA-N
Canonical SMILES	CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO
Isomeric SMILES	C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
RTECS	LZ7153000
PubChem CID	41774
Molecular Weight	645.61(as Anhydrous)
Reaxy-Rn	4898350

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Specific Rotation[α]	176° (C=1,H2O)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
RTECS	LZ7153000
Reaxy-Rn	4898350
Merck Index	18

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Qu-Jing Luo, Wen-Chao Zhou, Xin-Yi Liu, Ya-Jie Li, Qing-Ling Xie, Bin Wang, Chao Liu, Wen-Mao Wang, Wei Wang, Xu-Dong Zhou. (2023) Chemical Constituents and α-Glucosidase Inhibitory, Antioxidant and Hepatoprotective Activities of Ampelopsis grossedentata. MOLECULES, 28 (24): (7956). [PMID:38138447] [10.3390/molecules28247956]
2. Hui-Ting Cao, Tiansheng Zhao, Wei Liu, Cai-Ying Xu, Yi-Jing Liao, Xi-Luan Yan, Xi Mai, Na Li. (2024) Smartphone-assisted ratiometric fluorescence sensor for sensitive and portable α-glucosidase activity detection and inhibitor screening. MICROCHEMICAL JOURNAL, 197 (109723). [PMID:16303743] [10.1016/j.microc.2023.109723]
3. Si-Lu Wang, Jie Yu, Jian-Xi Song, Qing-Fan Meng, Zhuo-Rui Zhang, Gui-Quan Jiang. (2024) Isolation, purification, structural analysis and in vitro activity of polysaccharides from Amelanchier alnifolia Nutt.. PROCESS BIOCHEMISTRY, 136 (229). [PMID:] [10.1016/j.procbio.2023.12.002]
4. Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang, Jun Zhang. (2023) Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies. Foods, 12 (22): (4142). [PMID:38002199] [10.3390/foods12224142]
5. Yu Zheng, Ruifen Zhang, Fei Huang, Lai-Hoong Cheng, Liangxiong Xu, Xuchao Jia. (2023) α-Glucosidase inhibitors derived from black soybean and their inhibitory mechanisms. LWT-FOOD SCIENCE AND TECHNOLOGY, 189 (115502). [PMID:22808130] [10.1016/j.lwt.2023.115502]
6. Gonglin Cai, Hangmeng Dong, Shoulong Liu, Weijie Wu, Hailong Yang. (2023) Comparative Evaluation of the Physiochemical Properties, and Antioxidant and Hypoglycemic Activities of Dendrobium officinale Leaves Processed Using Different Drying Techniques. Antioxidants, 12 (11): (1911). [PMID:38001764] [10.3390/antiox12111911]
7. Na Li, Baijian Feng, Yongguang Bi, Fansheng Kong, Zhong Wang, Shaofan Tan. (2024) Sulfobutyl ether cyclodextrin inclusion complexes containing tea polyphenols: Preparation, characterization, antioxidant activity, α-glucosidase inhibition, and in vitro release property. JOURNAL OF MOLECULAR STRUCTURE, 1295 (21): (136686). [PMID:18819914] [10.1016/j.molstruc.2023.136686]
8. Zeng Xiang, Dai Huijia, Liu Bing, Wen Yao. (2023) Optimization of the extraction process and hypoglycemic activity of Tieguanyin tea polyphenols. Biomass Conversion and Biorefinery, (1-11). [PMID:15467718] [10.1007/s13399-023-04821-6]
9. Dan Yang, Xin-yu-yao Ding, Hai-Xia Xu, Yu-Xian Guo, Qing-Feng Zhang. (2023) Chemical profile of Roselle extract and its inhibitory activities on three digestive enzymes in vitro and in vivo. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (2): (126902). [PMID:37714233] [10.1016/j.ijbiomac.2023.126902]
10. Qianqian Feng, Wei Yang, Zhiyun Peng, Guangcheng Wang. (2023) Utilizing bio-affinity ultrafiltration combined with UHPLC Q-Exactive Plus Orbitrap HRMS to detect potential α-glucosidase inhibitors in Oxalis corniculate L.. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 252 (126490). [PMID:37625761] [10.1016/j.ijbiomac.2023.126490]
11. Yue-Hua Chen, Si-Yu Li, Dan Wang, Wei Yuan, Kun Xu, Jia-Wei Wang, Ting-Guo Kang, Hui Zhang. (2023) Combinatorics-based chemical characterization and bioactivity comparison of different parts of traditional Chinese medicinal plants through LC-Q-TOF-MS/MS, multivariate statistical analysis and bioassay: Marsdenia tenacissima as an example. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1228 (123850). [PMID:37598457] [10.1016/j.jchromb.2023.123850]
12. Jianjin GUO, Lu BAI, Chi-Tang HO, Sen GUO, Naisheng BAI. (2023) Chemical characterization, multivariate analysis and in vitro bioactivity evaluation of the roots of Fraxinus mandshurica. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 51 (100303). [PMID:] [10.1016/j.cjac.2023.100303]
13. Qinhao Guan, Lihua Tang, Liangliang Zhang, Lixin Huang, Man Xu, Yuan Wang, Meng Zhang. (2023) Molecular insights into α-glucosidase inhibition and antiglycation properties affected by the galloyl moiety in (−)-epigallocatechin-3-gallate. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (15): (7381-7392). [PMID:37390299] [10.1002/jsfa.12818]
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16. Huan Li, Jichen Yang, Mengfan Wang, Xiangzhao Ma, Xin Peng. (2023) Studies on the inhibition of α-glucosidase by biflavonoids and their interaction mechanisms. FOOD CHEMISTRY, 420 (136113). [PMID:37054519] [10.1016/j.foodchem.2023.136113]
17. Run Yu, Yue Li, Dun Si, Shulei Yan, Jingjing Liu, Jinping Si, Xinfeng Zhang. (2023) Identification, quantitative and bioactivity analyses of aroma and alcohol-soluble components in flowers of Gardenia jasminoides and its variety during different drying processes. FOOD CHEMISTRY, 420 (135846). [PMID:37060668] [10.1016/j.foodchem.2023.135846]
18. Yao Wen, Caimei Su. (2023) Optimization of Ultrasonic Assisted Extraction and Bioactivity of Ophiopogon japonicus Polysaccharides by Response Surface Methodology. STARCH-STARKE, 75 (3-4): (2200213). [PMID:] [10.1002/star.202200213]
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20. Shuang Qi, Bo Jiang, Caoxing Huang, Yongcan Jin. (2023) Dual Regulation of Sulfonated Lignin to Prevent and Treat Type 2 Diabetes Mellitus. BIOMACROMOLECULES, 24 (2): (841–848). [PMID:36608216] [10.1021/acs.biomac.2c01267]
21. Xi Peng, Kai Liu, Xing Hu, Deming Gong, Guowen Zhang. (2023) Hesperetin-Cu(II) complex as potential α-amylase and α-glucosidase inhibitor: Inhibition mechanism and molecular docking. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 290 (122301). [PMID:36603279] [10.1016/j.saa.2022.122301]
22. Huihui Liu, Chang Zheng, Ziliang Li, Xiaoyang Xia, Dan Jiang, Wen Wang, Ruiying Zhang, Xia Xiang. (2023) Inhibitory mechanism of phenolic compounds in rapeseed oil on α-amylase and α-glucosidase: Spectroscopy, molecular docking, and molecular dynamic simulation. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 289 (122251). [PMID:36542921] [10.1016/j.saa.2022.122251]
23. Xiu-Qing Song, Lin-Lin Tian, Tao Ye, Hu Liu, Hua Zhang. (2023) Steroid glycosides from the roots of Marsdenia tenacissima. PHYTOCHEMISTRY, 205 (113506). [PMID:36347308] [10.1016/j.phytochem.2022.113506]
24. Jing Lei, Wei Li, Meng-Xi Fu, An-Qi Wang, Ding-Tao Wu, Huan Guo, Yi-Chen Hu, Ren-You Gan, Liang Zou, Ying Liu. (2022) Pressurized hot water extraction, structural properties, biological effects, and in vitro microbial fermentation characteristics of sweet tea polysaccharide. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 222 (3215). [PMID:36243163] [10.1016/j.ijbiomac.2022.10.094]
25. Shan-Shan Zhang, Yu-Fei Hou, Shao-Jing Liu, Sen Guo, Chi-Tang Ho, Nai-Sheng Bai. (2022) Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota. Nutrients, 14 (19): (3980). [PMID:36235633] [10.3390/nu14193980]
26. Chen Shanji, Tian Danmei, Wei Jihua, Li Cong, Ma Yihan, Gou Xiaoshuang, Shen Yiran, Chen Mei, Zhang Sihao, Li Jia, Wu Bin, Tang Jinshan. (2022) Citrinin Derivatives From Penicillium Citrinum Y34 That Inhibit α-Glucosidase and ATP-Citrate Lyase. Frontiers in Marine Science, 9 [PMID:] [10.3389/fmars.2022.961356]
27. Wei Liu, Liang Ma, Liping Zhang, Yuchan Chen, Qingbo Zhang, Haibo Zhang, Weimin Zhang, Changsheng Zhang, Wenjun Zhang. (2022) Two New Phenylhydrazone Derivatives from the Pearl River Estuary Sediment-Derived Streptomyces sp. SCSIO 40020. Marine Drugs, 20 (7): (449). [PMID:35877742] [10.3390/md20070449]
28. Jiahe Fan, Chaoyi Lv, Zhizhou Li, Mengru Guo, Yichen Yin, Hui Wang, Wei Wang, Shiwei Sun. (2022) α-Glucosidase inhibitory effect of an anthraquinonoid produced by Fusarium incarnatum GDZZ-G2. JOURNAL OF BASIC MICROBIOLOGY, 62 (11): (1360-1370). [PMID:35736630] [10.1002/jobm.202200166]
29. Xiaoli Wang, Jichen Yang, Huan Li, Se Shi, Xin Peng. (2022) Mechanistic study and synergistic effect on inhibition of α-amylase by structurally similar flavonoids. JOURNAL OF MOLECULAR LIQUIDS, 360 (119485). [PMID:] [10.1016/j.molliq.2022.119485]
30. Peng-Bo Duan, Ping-Ting Xiao, Xing Yang, Jin-Hua Hao, Kai Li, E-Hu Liu. (2022) Screening of hypoglycemic components in Platycladi Cacumen by phytochemical investigation, spectrum-effect relationship, and chemometric methods. JOURNAL OF SEPARATION SCIENCE, 45 (14): (2591-2602). [PMID:35593082] [10.1002/jssc.202200221]
31. Xinyue Zhang, Rizwan-ur Rehman, Songxue Wang, Yanglin Ji, Jing Li, Suwen Liu, Hao Wang. (2022) Blue honeysuckle extracts retarded starch digestion by inhibiting glycosidases and changing the starch structure. Food & Function, 13 (11): (6072-6088). [PMID:35550649] [10.1039/D2FO00459C]
32. Jie Liu, Fang-Fang Wang, Zheng-Meng Jiang, E-Hu Liu. (2022) Identification of antidiabetic components in Uncariae Rammulus Cum Uncis based on phytochemical isolation and spectrum–effect relationship analysis. PHYTOCHEMICAL ANALYSIS, 33 (5): (659-669). [PMID:35261095] [10.1002/pca.3118]
33. Shan-Shan Zhang, Niu-Niu Zhang, Sen Guo, Shao-Jing Liu, Yu-Fei Hou, Shiming Li, Chi-Tang Ho, Nai-Sheng Bai. (2022) Glycosides and flavonoids from the extract of Pueraria thomsonii Benth leaf alleviate type 2 diabetes in high-fat diet plus streptozotocin-induced mice by modulating the gut microbiota. Food & Function, 13 (7): (3931-3945). [PMID:35289350] [10.1039/D1FO04170C]
34. Ying Zhang, Yanna Pan, Jiaqi Li, Zeng Zhang, Yanming He, Hongjie Yang, Ping Zhou. (2022) Inhibition on α-Glucosidase Activity and Non-Enzymatic Glycation by an Anti-Oxidative Proteoglycan from Ganoderma lucidum. MOLECULES, 27 (5): (1457). [PMID:35268560] [10.3390/molecules27051457]
35. Hui Wang, Xiaoli Kang, Shiwei Sun, Yichen Yin, Kun Jiang, Guodong Tang, Xinning Tang, Wei Wang. (2022) Discovery of pyrogallol thermal reaction products from a model process of roasting coffee beans as potent α-glucosidase inhibitors. Food Bioscience, 46 (101583). [PMID:] [10.1016/j.fbio.2022.101583]
36. De-Fu Hong, Gui-Lin Hu, Xing-Rong Peng, Xiao-Yuan Wang, Yan-Bing Wang, Abdulbaset Al-Romaima, Zhong-Rong Li, Ming-Hua Qiu. (2022) Unusual ent-Kaurane Diterpenes from the Coffea Cultivar S288 Coffee Beans and Molecular Docking to α-Glucosidase. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (2): (615–625). [PMID:35005957] [10.1021/acs.jafc.1c06524]
37. Jinjin Zhao, Zhangtie Wang, Emad Karrar, Deping Xu, Xiulan Sun. (2022) Inhibition Mechanism of Berberine on α-Amylase and α-Glucosidase in Vitro. STARCH-STARKE, 74 (3-4): (2100231). [PMID:] [10.1002/star.202100231]
38. Chen Yu, Zi-Yi Yu, Yi-Ting Wen, Wei-Ming Chai, Lin-Jun Wang, Mei-Zhen Lin. (2022) Omeprazole inhibits α-glucosidase activity and the formation of nonenzymatic glycation products: Activity and mechanism. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 133 (110). [PMID:34802943] [10.1016/j.jbiosc.2021.10.007]
39. Yun-Lai Liu, Yong Wang, Xiao-Ru He, Li-She Gan, Fan Xu, Yun-Jing Xu, Xiao-Ning Wang, Tao Shen, Zhi-Wang Zhou. (2022) Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities. FITOTERAPIA, 156 (105086). [PMID:34798164] [10.1016/j.fitote.2021.105086]
40. Jiale Cai, Xiaoting Zhong, Jiayin Liang, Can Xu, Huanzheng Yu, Minghua Xian, Chunyan Yan, Shumei Wang. (2021) Structural characterization, anti-inflammatory and glycosidase inhibitory activities of two new polysaccharides from the root of Pueraria lobata. RSC Advances, 11 (57): (35994-36006). [PMID:35492792] [10.1039/D1RA07385K]
41. Jinjin Zhao, Zhangtie Wang, Deping Xu, Xiulan Sun. (2021) Identification of antidiabetic components from Cyclocarya paliurus. Food Bioscience, 44 (101429). [PMID:] [10.1016/j.fbio.2021.101429]
42. Zhenfeng Huang, You Luo, Xuesen Xia, Anping Wu, Zhenqiang Wu. (2021) Bioaccessibility, safety, and antidiabetic effect of phenolic-rich extract from fermented Psidium guajava Linn. leaves. Journal of Functional Foods, 86 (104723). [PMID:] [10.1016/j.jff.2021.104723]
43. Jichen Yang, Huan Li, Xiaoli Wang, Chuanying Zhang, Guo Feng, Xin Peng. (2021) Inhibition Mechanism of α-Amylase/α-Glucosidase by Silibinin, Its Synergism with Acarbose, and the Effect of Milk Proteins. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (36): (10515–10526). [PMID:34463509] [10.1021/acs.jafc.1c01765]
44. Shouye Han, Yu Liu, Wan Liu, Fan Yang, Jia Zhang, Ruifeng Liu, Fenqin Zhao, Wei Xu, Zhongbin Cheng. (2021) Chromone Derivatives with α-Glucosidase Inhibitory Activity from the Marine Fungus Penicillium thomii Maire. MOLECULES, 26 (17): (5273). [PMID:34500706] [10.3390/molecules26175273]
45. Limin Wang, Yunsen Zhang, I. Agbaka Johnpaul, Kai Hong, Yumei Song, Xiao Yang, Chenyan Lv, Changwei Ma. (2022) Exploring two types of prenylated bitter compounds from hop plant (Humulus lupulus L.) against α-glucosidase in vitro and in silico. FOOD CHEMISTRY, 370 (130979). [PMID:34543921] [10.1016/j.foodchem.2021.130979]
46. Ju-Zhen Yi, Kunhua Lin, Hao Wu, Xuhong Mao, Li-Ming Zhang, Liqun Yang. (2021) Smart controlled release of acarbose from glucose-sensitive hydrogels comprising covalently modified carboxylated pullulan and concanavalin A. JOURNAL OF APPLIED POLYMER SCIENCE, 138 (48): (51553). [PMID:] [10.1002/app.51553]
47. Tao Tian, Guo-Ying Chen, Hao Zhang, Feng-Qing Yang. (2021) Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose. MOLECULES, 26 (15): (4638). [PMID:34361791] [10.3390/molecules26154638]
48. Jinxiang Huang, Xufeng Zang, Wuying Yang, Xiaoli Yin, Jianping Huang, Shumin Wu, Yanping Hong. (2021) Pentacyclic triterpene carboxylic acids derivatives integrated piperazine-amino acid complexes for α-glucosidase inhibition in vitro. BIOORGANIC CHEMISTRY, 115 (105212). [PMID:34333423] [10.1016/j.bioorg.2021.105212]
49. Ying Li, Bo Chen, Hai-Yan Cao, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Pancreatic lipase inhibitory activity of Bambusa multiplex cv. Fernleaf leaf extract in vitro and in vivo. Food & Function, 12 (16): (7440-7447). [PMID:34195734] [10.1039/D1FO01168E]
50. Hui Zhang, Ruoyu Chen, Cong Xu, Guimin Zhang, Yongxia Guan, Qun Feng, Jingchun Yao, Jizhong Yan. (2021) An integrated approach to discriminate the quality markers of Traditional Chinese medicine preparation based on multi-dimensional characteristic network: Shenqi Jiangtang Granule as a case. JOURNAL OF ETHNOPHARMACOLOGY, 278 (114277). [PMID:34089811] [10.1016/j.jep.2021.114277]
51. Ke Zhao, Shiwei Sun, Hui Wang, Lin Wang, Guoqing Qin, Jiahe Fan, Mengru Guo, Wei Wang. (2021) α-Glucosidase inhibitory triterpenoids from Euonymus fortunei. BIOORGANIC CHEMISTRY, 111 (104980). [PMID:34004587] [10.1016/j.bioorg.2021.104980]
52. Yiming Zhou, Qingyi Jiang, Sijia Ma, Xiaoli Zhou. (2021) Effect of quercetin on the in vitro Tartary buckwheat starch digestibility. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 183 (818). [PMID:33965481] [10.1016/j.ijbiomac.2021.05.013]
53. Hua Guo, Yue-Hua Chen, Tian-Min Wang, Ting-Guo Kang, Hui-Yang Sun, Wen-Han Pei, Hui-Peng Song, Hui Zhang. (2021) A strategy to discover selective α-glucosidase/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1174 (122722). [PMID:33992880] [10.1016/j.jchromb.2021.122722]
54. Xie Zhike, He Ming, Zhai Yuhan, Xin Feifei, Yu Shuyan, Yu Shaoxuan, Xiao Haifang, Song Yuanda. (2021) Inhibitory kinetics and mechanism of oleanolic acid on α-glucosidase. Journal of Food Measurement and Characterization, 15 (4): (3408-3418). [PMID:] [10.1007/s11694-021-00920-y]
55. Yanglin Ji, Dong Liu, Yan jin, Juan Zhao, Jiang Zhao, Heyu Li, Liwei Li, Hua Zhang, Hao Wang. (2021) In vitro and in vivo inhibitory effect of anthocyanin-rich bilberry extract on α-glucosidase and α-amylase. LWT-FOOD SCIENCE AND TECHNOLOGY, 145 (111484). [PMID:] [10.1016/j.lwt.2021.111484]
56. Min Lu, Hao Zhang, Xu Wang, Hui Jiang, Guang Hu, Feng-Qing Yang. (2021) Preparation of phytic acid modified α-Glucosidase/Cu3(PO4)2·3H2O hybrid nanoflower and its application. ENZYME AND MICROBIAL TECHNOLOGY, 146 (109776). [PMID:33812564] [10.1016/j.enzmictec.2021.109776]
57. Li Cong, Zi Yuqiu, Xu Dawei, Jiang Dafeng, Qu Fei, Zhao Xian-En. (2021) A fluorescence strategy for monitoring α-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413 (9): (2553-2563). [PMID:33575817] [10.1007/s00216-021-03214-w]
58. Chunfang Yang, Chunshuai Huang, Chunyan Fang, Liping Zhang, Siqiang Chen, Qingbo Zhang, Changsheng Zhang, Wenjun Zhang. (2021) Inactivation of Flavoenzyme-Encoding Gene flsO1 in Fluostatin Biosynthesis Leads to Diversified Angucyclinone Derivatives. JOURNAL OF ORGANIC CHEMISTRY, 86 (16): (11019–11028). [PMID:33534573] [10.1021/acs.joc.0c02517]
59. Hao Zhong, Abdullah, Minjie Zhao, Jun Tang, Lingli Deng, Fengqin Feng. (2021) Probiotics-fermented blueberry juices as potential antidiabetic product: antioxidant, antimicrobial and antidiabetic potentials. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (10): (4420-4427). [PMID:33421121] [10.1002/jsfa.11083]
60. Xiu-Qing Song, Jin-Hai Yu, Jia Sun, Kai-Lu Liu, Jun-Sheng Zhang, Hua Zhang. (2021) Bioactive sesquiterpenoids from the flower buds of Tussilago farfara. BIOORGANIC CHEMISTRY, 107 (104632). [PMID:33450544] [10.1016/j.bioorg.2021.104632]
61. GuiLin Hu, XingRong Peng, Ding Dong, Yin Nian, Ya Gao, XiaoYuan Wang, DeFu Hong, MingHua Qiu. (2021) New ent-kaurane diterpenes from the roasted arabica coffee beans and molecular docking to α-glucosidase. FOOD CHEMISTRY, 345 (128823). [PMID:33341560] [10.1016/j.foodchem.2020.128823]
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Acarbose Hydrate - 10mM in DMSO, high purity , Maltase-glucoamylase inhibitor, CAS No.56180-94-0, Maltase-glucoamylase inhibitor