Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A194116-5g | 5g | In stock | $19.90 | |
A194116-25g | 25g | In stock | $69.90 | |
A194116-100g | 100g | In stock | $179.90 | |
A194116-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $579.90 |
Non-specific carbonic anhydrase inhibitor
Synonyms | acetazolamide | 59-66-5 | Diamox | Acetamox | Nephramide | Glaupax | N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Acetazolamid | Defiltran | Phonurit | Donmox | Edemox | Didoc | Diuriwas | Cidamex | Diacarb | Diluran | Dehydratin | Natrionex | Nephramid | Diakarb | Diuramid | Diutazol | Duiramid | |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | Non-specific carbonic anhydrase inhibitor with diverse physiological effects that are cell and tissue specific. Heterocyclic primary sulfonamide. |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of carbonic anhydrase 1;Inhibitor of carbonic anhydrase 12;Inhibitor of carbonic anhydrase 13;Inhibitor of carbonic anhydrase 14;Inhibitor of carbonic anhydrase 4;Inhibitor of carbonic anhydrase 7 |
Product Description | Acetazolamide is a carbonic anhydrase (CA) IX inhibitor, which inhibits HCA IX with IC50 of 30 nm. diuretic. |
ALogP | -0.3 |
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Pubchem Sid | 488179648 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179648 |
IUPAC Name | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide |
INCHI | InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
InChi Key | BZKPWHYZMXOIDC-UHFFFAOYSA-N |
Canonical SMILES | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
Isomeric SMILES | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
RTECS | AC8225000 |
PubChem CID | 1986 |
Molecular Weight | 222.25 |
Reaxy-Rn | 212994 |
DrugBank Ligand | DB00819 |
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PubChem CID | 1986 |
CAS Registry No. | 59-66-5 |
ChEMBL Ligand | CHEMBL20 |
Wikipedia | Acetazolamide |
RCSB PDB Ligand | AZM |
PEP | acetazolamide |
DrugCentral Ligand | 56 |
PubChem SID | 488179648 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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A2408278 | Certificate of Analysis | Dec 20, 2023 | A194116 |
A2408279 | Certificate of Analysis | Dec 20, 2023 | A194116 |
A2408280 | Certificate of Analysis | Dec 20, 2023 | A194116 |
A2408281 | Certificate of Analysis | Dec 20, 2023 | A194116 |
E2424079 | Certificate of Analysis | Dec 20, 2023 | A194116 |
D2301034 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301035 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301036 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301037 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301038 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301039 | Certificate of Analysis | Mar 21, 2023 | A194116 |
D2301047 | Certificate of Analysis | Mar 21, 2023 | A194116 |
J2316013 | Certificate of Analysis | Mar 21, 2023 | A194116 |
H2224442 | Certificate of Analysis | Jul 25, 2022 | A194116 |
H2224443 | Certificate of Analysis | Jul 25, 2022 | A194116 |
H2224519 | Certificate of Analysis | Jul 25, 2022 | A194116 |
Solubility | Soluble in NH4OH (50 mg/mL), DMSO, Methanol and slightly soluble in Ethanol. |
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Sensitivity | Light sensitive |
Melt Point(°C) | 255℃ |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
RTECS | AC8225000 |
Reaxy-Rn | 212994 |
Starting at $69.90
Starting at $213.90
1. Haoyu Long, Yanhao Jiang, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang. (2023) Chromatographic separation performance of silica microspheres surface-modified with triazine-containing imine-linked covalent organic frameworks. TALANTA, 260 (124589). [PMID:37126925] |
1. Haoyu Long, Yanhao Jiang, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang. (2023) Chromatographic separation performance of silica microspheres surface-modified with triazine-containing imine-linked covalent organic frameworks. TALANTA, 260 (124589). [PMID:37126925] |