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Acetylcholine chloride - 99%, high purity , CAS No.60-31-1

9 Citations

≥99%

CAS#: 60-31-1
Formula: C₇H₁₆ClNO₂
Molecular Weight: 181.66
Beilstein Registry Number: 3571875
EC Number: 200-468-8
MDL number: MFCD00011698
PubChem CID: 6060

Item Number

A111014

Grouped product items
SKU	Size	Availability	Price
A111014-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90
A111014-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$477.90
A111014-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,717.90

Endogenous neurotransmitter

View related series

Ammonium salt Cell signal transduction and Neuroscience

Basic Description

Synonyms	ACETYLCHOLINE CHLORIDE \| 60-31-1 \| Miochol \| Acecoline \| Acecholin \| ACH chloride \| Chloroacetylcholine \| Arterocoline \| Ovisot \| Azetylcholinchlorid \| 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride \| MIOCHOL-E \| Acetylcholinium chloride \| O-Acetylcholine chloride \| 2-Acetoxyeth
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors.
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Acetylcholine chloride, more commonly referred to as just acetylcholine, is a cholinergic neurotransmitter that can induce the opening of calcium channels, as well as act on nicotinic and muscarinic acetylcholine receptors. Acetylcholine plays an important role at many sites in the central nervous system. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Studies show that non-neuronal acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. A cholinergic neurotransmitter that can induce the opening of calcium channels

Associated Targets(Human)

CBX1 Tbio Chromobox protein homolog 1 (0 Activities)

Discover Target: CBX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPC4 Tchem Short transient receptor potential channel 4 (0 Activities)

Discover Target: TRPC4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TNNC1 Tclin Troponin C, slow skeletal and cardiac muscles (0 Activities)

Discover Target: TNNC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC5A7 Tchem High affinity choline transporter 1 (0 Activities)

Discover Target: SLC5A7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (0 Activities)

Discover Target: CHRM5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)

Discover Target: CHRM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (0 Activities)

Discover Target: CHRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TARDBP Tchem TAR DNA-binding protein 43 (0 Activities)

Discover Target: TARDBP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)

Discover Target: GLP1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)

Discover Target: CHRM5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)

Discover Target: CHRM3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC5A7 Tchem High-affinity choline transporter (1462 Activities)

Discover Target: SLC5A7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TNNC1 Tclin Troponin, cardiac muscle (276 Activities)

Discover Target: TNNC1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

Discover Target: TARDBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Klebsiella pneumoniae (43867 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Acinetobacter baumannii (41033 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cryptococcus neoformans (21258 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trpc4 Short transient receptor potential channel 4 (1615 Activities)

Discover Target: Trpc4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-acetyloxyethyl(trimethyl)azanium;chloride
INCHI	InChI=1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChi Key	JUGOREOARAHOCO-UHFFFAOYSA-M
Canonical SMILES	CC(=O)OCC[N+](C)(C)C.[Cl-]
Isomeric SMILES	CC(=O)OCC[N+](C)(C)C.[Cl-]
WGK Germany	2
RTECS	FZ9800000
PubChem CID	6060
Molecular Weight	181.66
Beilstein	3571875
Reaxy-Rn	3571875

Certificates

Certificate of Analysis(COA)

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20 results found

Lot Number	Certificate Type	Date	Item
D2429098	Certificate of Analysis	Mar 18, 2024	A111014
D2429097	Certificate of Analysis	Mar 18, 2024	A111014
D2429096	Certificate of Analysis	Mar 18, 2024	A111014
D2429095	Certificate of Analysis	Mar 18, 2024	A111014
D2407105	Certificate of Analysis	Mar 08, 2024	A111014
D2407106	Certificate of Analysis	Mar 08, 2024	A111014
D2407107	Certificate of Analysis	Mar 08, 2024	A111014
C2414105	Certificate of Analysis	Feb 26, 2024	A111014
C2414107	Certificate of Analysis	Feb 26, 2024	A111014
C2414106	Certificate of Analysis	Feb 26, 2024	A111014
C2414104	Certificate of Analysis	Feb 26, 2024	A111014
H2330066	Certificate of Analysis	Aug 21, 2023	A111014
H2330067	Certificate of Analysis	Aug 21, 2023	A111014
H2330068	Certificate of Analysis	Aug 21, 2023	A111014
H2330061	Certificate of Analysis	Aug 15, 2023	A111014
H2330063	Certificate of Analysis	Aug 15, 2023	A111014
H2330064	Certificate of Analysis	Aug 15, 2023	A111014
J2209009	Certificate of Analysis	Sep 08, 2022	A111014
J2209012	Certificate of Analysis	Sep 08, 2022	A111014
J2209013	Certificate of Analysis	Sep 08, 2022	A111014

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 18.17, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 18.17, Max Conc. mM: 100
Sensitivity	Light, Moisture and Heat Sensitive
Melt Point(°C)	149-152°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	FZ9800000
Reaxy-Rn	3571875
Merck Index	87

Alternative Products

FAQs and Articles

FAQ

Metabolic signaling pathway

Categories: Technical articles

Tags:

Carbohydrate metabolism Lipid metabolism Glutamic acid metabolism Nucleotide metabolism

The Key Molecule in Neurotransmission—Acetylcholine

Categories: Technical articles

Tags:

Metabolites Acetylcholine Nucleosides and nucleotides Coenzymes In vitro diagnostics Metabolism Neuroscience Nerve signaling

Citations of This Product

1. Li Qiwei, Chen Zaozao, Zhang Ying, Ding Shuang, Ding Haibo, Wang Luping, Xie Zhuoying, Fu Yifu, Wei Mengxiao, Liu Shengnan, Chen Jialun, Wang Xuan, Gu Zhongze. (2023) Imaging cellular forces with photonic crystals. Nature Communications, 14 (1): (1-14). [PMID:37963911]
2. Guorui Chang, Sirui Li, Yunqi Wang, Qingxia Ran, Qing Tan, Shuli Gou, Haiying Du, Shuxia Xu. (2024) Cu-C3N4 nanoenzyme-based freezing-dried bioactive capsule integrated with 3D-printed smartphone platform for visual detection of organophosphorus pesticides paraoxon in scallion. SENSORS AND ACTUATORS B-CHEMICAL, 398 (1): (134584). [PMID:17505538]
3. Zhe Ling, Yang Tan, Xinjian Li, Ying Xie, Peng Wang, Yan Su, Qiang Yong. (2023) Elucidating multi-scale deconstruction of bamboo crystalline cellulose by novel acetylcholine chloride based deep eutectic solvents for enhanced enzymatic hydrolysis. INDUSTRIAL CROPS AND PRODUCTS, 203 (117156). [PMID:]
4. Yaxu Zhao, Lijun Liang, Wei Guo, Xiong Lu, Congyi Zhao, Faming Gao. (2023) The porous hollow cobalt-based oxides encapsulated with bimetallic PdAu Nanoparticles of electrochemical biosensor for highly sensitive pesticides detection. NANOTECHNOLOGY, 34 (28): (285501). [PMID:37054697]
5. Zhou Liping, Lao Zishan, Fan Xinsheng, Hao Mengyang, Yang Yubing. (2023) Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, [PMID:37073125]
6. Wang Kai, Liang Yaping, Duan Manman, Che Wunan, He Lu. (2023) Chronic toxicity of broflanilide in Daphnia magna: changes in molting, behavior, and gene expression. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (19): (54846-54856). [PMID:36881221]
7. Haoge Cheng, Kaiyue Yang, Yuze Zhang, Shenglong Liao, Menghao Du, Jiaqi Li, Ning Ma, Mianqi Xue, Xinyue Zhang, Yapei Wang. (2022) A Novel Ionic Conductive Polyurethane Based on Deep Eutectic Solvent Continuing Traditional Merits. ACS Applied Materials & Interfaces, 14 (46): (52402–52410). [PMID:36256442]
8. Hangjing Zhang, Tianyuan Gao, Lei Jiang, Xiangqi Meng, Jian Wang, Ning Ma, Hao Wei, Xinyue Zhang. (2022) Conductive and transparent poly (N-isopropylacrylamide) hydrogels with tunable LCST copolymerized by the green acrylamide-based deep eutectic solvent. EUROPEAN POLYMER JOURNAL, 173 (111266). [PMID:]
9. Zhiang Zhang, Jikun Jiang, Xiao (Xiao) Liu, Xin Wang, Luyao Wang, Yuankun Qiu, Zhanfei Zhang, Yiting Zheng, Xueyun Wu, Jianghu Liang, Congcong Tian, Chun-Chao Chen. (2021) Surface-Anchored Acetylcholine Regulates Band-Edge States and Suppresses Ion Migration in a 21%-Efficient Quadruple-Cation Perovskite Solar Cell. Small, 18 (6): (2105184). [PMID:34851037]

References

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