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Acetylcholine chloride - 99%, high purity , CAS No.60-31-1

13 Citations

≥99%

CAS#: 60-31-1
Formula: C₇H₁₆ClNO₂
Molecular Weight: 181.66
Beilstein Registry Number: 3571875
EC Number: 200-468-8
MDL number: MFCD00011698
PubChem CID: 6060

Item Number

A111014

Grouped product items
SKU	Size	Availability	Price
A111014-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90
A111014-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$477.90
A111014-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,717.90

Endogenous neurotransmitter

View related series

Ammonium salt Calcium Channel Cell signal transduction and Neuroscience Endogenous Metabolite Membrane Transporter/Ion Channel Metabolic Enzyme/Protease nAChR Neuronal Signaling

Basic Description

Synonyms	ACh \| MLS000028640 \| NCGC00018123-07 \| SCHEMBL40885 \| Acetylcholine chloride (USP:INN:BAN:JAN) \| Acetylcholine hydrochloride \| AI3-51676 \| REGID_for_CID_6060 \| 2-acetyloxy-N,N,N-trimethylethanaminium chloride \| AKOS005111031 \| O-Acetylcholine chloride \| 2
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors.
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Acetylcholine chloride, more commonly referred to as just acetylcholine, is a cholinergic neurotransmitter that can induce the opening of calcium channels, as well as act on nicotinic and muscarinic acetylcholine receptors. Acetylcholine plays an important role at many sites in the central nervous system. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Studies show that non-neuronal acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. A cholinergic neurotransmitter that can induce the opening of calcium channels

Associated Targets(Human)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)

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CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)

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GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

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Homo sapiens (32628 Activities)

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SLC5A7 Tchem High-affinity choline transporter (1462 Activities)

Discover Target: SLC5A7

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

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TNNC1 Tclin Troponin, cardiac muscle (276 Activities)

Discover Target: TNNC1

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Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Plasmodium falciparum (966862 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Trpc4 Short transient receptor potential channel 4 (1615 Activities)

Discover Target: Trpc4

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vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-acetyloxyethyl(trimethyl)azanium;chloride
INCHI	InChI=1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChi Key	JUGOREOARAHOCO-UHFFFAOYSA-M
Canonical SMILES	CC(=O)OCC[N+](C)(C)C.[Cl-]
Isomeric SMILES	CC(=O)OCC[N+](C)(C)C.[Cl-]
WGK Germany	2
RTECS	FZ9800000
PubChem CID	6060
Molecular Weight	181.66
Beilstein	3571875
Reaxy-Rn	3571875

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

23 results found

Lot Number	Certificate Type	Date	Item
K2413158	Certificate of Analysis	Nov 23, 2024	A111014
K2413157	Certificate of Analysis	Nov 23, 2024	A111014
K2413154	Certificate of Analysis	Nov 23, 2024	A111014
D2429095	Certificate of Analysis	Mar 18, 2024	A111014
D2429096	Certificate of Analysis	Mar 18, 2024	A111014
D2429097	Certificate of Analysis	Mar 18, 2024	A111014
D2429098	Certificate of Analysis	Mar 18, 2024	A111014
D2407105	Certificate of Analysis	Mar 08, 2024	A111014
D2407106	Certificate of Analysis	Mar 08, 2024	A111014
D2407107	Certificate of Analysis	Mar 08, 2024	A111014
C2414105	Certificate of Analysis	Feb 26, 2024	A111014
C2414107	Certificate of Analysis	Feb 26, 2024	A111014
C2414106	Certificate of Analysis	Feb 26, 2024	A111014
C2414104	Certificate of Analysis	Feb 26, 2024	A111014
H2330066	Certificate of Analysis	Aug 21, 2023	A111014
H2330067	Certificate of Analysis	Aug 21, 2023	A111014
H2330068	Certificate of Analysis	Aug 21, 2023	A111014
H2330061	Certificate of Analysis	Aug 15, 2023	A111014
H2330063	Certificate of Analysis	Aug 15, 2023	A111014
H2330064	Certificate of Analysis	Aug 15, 2023	A111014
J2209009	Certificate of Analysis	Sep 08, 2022	A111014
J2209012	Certificate of Analysis	Sep 08, 2022	A111014
J2209013	Certificate of Analysis	Sep 08, 2022	A111014

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Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 18.17, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 18.17, Max Conc. mM: 100
Sensitivity	Light, Moisture and Heat Sensitive
Melt Point(°C)	149-152°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	FZ9800000
Reaxy-Rn	3571875
Merck Index	87

Alternative Products

FAQs and Articles

FAQ

Metabolic signaling pathway

Categories: Technical articles

Tags:

Carbohydrate metabolism Lipid metabolism Glutamic acid metabolism Nucleotide metabolism

The Key Molecule in Neurotransmission—Acetylcholine

Categories: Technical articles

Tags:

Metabolites Acetylcholine Nucleosides and nucleotides Coenzymes In vitro diagnostics Metabolism Neuroscience Nerve signaling

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Li Qiwei, Chen Zaozao, Zhang Ying, Ding Shuang, Ding Haibo, Wang Luping, Xie Zhuoying, Fu Yifu, Wei Mengxiao, Liu Shengnan, Chen Jialun, Wang Xuan, Gu Zhongze. (2023) Imaging cellular forces with photonic crystals. Nature Communications, 14 (1): (1-14). [PMID:37963911] [10.1038/s41467-023-43090-9]
2. Guorui Chang, Sirui Li, Yunqi Wang, Qingxia Ran, Qing Tan, Shuli Gou, Haiying Du, Shuxia Xu. (2024) Cu-C3N4 nanoenzyme-based freezing-dried bioactive capsule integrated with 3D-printed smartphone platform for visual detection of organophosphorus pesticides paraoxon in scallion. SENSORS AND ACTUATORS B-CHEMICAL, 398 (1): (134584). [PMID:17505538] [10.1016/j.snb.2023.134584]
3. Zhe Ling, Yang Tan, Xinjian Li, Ying Xie, Peng Wang, Yan Su, Qiang Yong. (2023) Elucidating multi-scale deconstruction of bamboo crystalline cellulose by novel acetylcholine chloride based deep eutectic solvents for enhanced enzymatic hydrolysis. INDUSTRIAL CROPS AND PRODUCTS, 203 (117156). [PMID:] [10.1016/j.indcrop.2023.117156]
4. Yaxu Zhao, Lijun Liang, Wei Guo, Xiong Lu, Congyi Zhao, Faming Gao. (2023) The porous hollow cobalt-based oxides encapsulated with bimetallic PdAu Nanoparticles of electrochemical biosensor for highly sensitive pesticides detection. NANOTECHNOLOGY, 34 (28): (285501). [PMID:37054697] [10.1088/1361-6528/accc8f]
5. Zhou Liping, Lao Zishan, Fan Xinsheng, Hao Mengyang, Yang Yubing. (2023) Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, [PMID:37073125] [10.1093/bbb/zbad039]
6. Wang Kai, Liang Yaping, Duan Manman, Che Wunan, He Lu. (2023) Chronic toxicity of broflanilide in Daphnia magna: changes in molting, behavior, and gene expression. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (19): (54846-54856). [PMID:36881221] [10.1007/s11356-023-26255-3]
7. Haoge Cheng, Kaiyue Yang, Yuze Zhang, Shenglong Liao, Menghao Du, Jiaqi Li, Ning Ma, Mianqi Xue, Xinyue Zhang, Yapei Wang. (2022) A Novel Ionic Conductive Polyurethane Based on Deep Eutectic Solvent Continuing Traditional Merits. ACS Applied Materials & Interfaces, 14 (46): (52402–52410). [PMID:36256442] [10.1021/acsami.2c15356]
8. Hangjing Zhang, Tianyuan Gao, Lei Jiang, Xiangqi Meng, Jian Wang, Ning Ma, Hao Wei, Xinyue Zhang. (2022) Conductive and transparent poly (N-isopropylacrylamide) hydrogels with tunable LCST copolymerized by the green acrylamide-based deep eutectic solvent. EUROPEAN POLYMER JOURNAL, 173 (111266). [PMID:] [10.1016/j.eurpolymj.2022.111266]
9. Zhiang Zhang, Jikun Jiang, Xiao (Xiao) Liu, Xin Wang, Luyao Wang, Yuankun Qiu, Zhanfei Zhang, Yiting Zheng, Xueyun Wu, Jianghu Liang, Congcong Tian, Chun-Chao Chen. (2021) Surface-Anchored Acetylcholine Regulates Band-Edge States and Suppresses Ion Migration in a 21%-Efficient Quadruple-Cation Perovskite Solar Cell. Small, 18 (6): (2105184). [PMID:34851037] [10.1002/smll.202105184]
10. Xinyue Dai, Kai Le, Fenglong Wang, Rubin Wei, Jiurong Liu, Yanyan Jiang, Hui Li. (2020) Single-Molecule Detection of Acetylcholine by Translating the Neuronal Signal to a Single Distinct Electronic Peak. ACS Applied Bio Materials, 3 (10): (6888–6896). [PMID:35019350] [10.1021/acsabm.0c00797]
11. Zhijiao Tang, Zhengyi Chen, Gongke Li, Yuling Hu. (2020) Multicolor nitrogen dots for rapid detection of thiram and chlorpyrifos in fruit and vegetable samples. ANALYTICA CHIMICA ACTA, 1136 (72). [PMID:33081951] [10.1016/j.aca.2020.08.038]
12. Benhong Xu, Huixing Deng, Xiaojing Zhang, Jingxiong Luo, Gaoxiao Zhang, Zaijun Zhang, Yuqiang Wang, Luchen Shan. (2018) A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs. EUROPEAN JOURNAL OF PHARMACOLOGY, 818 (158). [PMID:29066416] [10.1016/j.ejphar.2017.10.034]
13. Lve Wang, Xu Chen, Changxia Liu, Wensheng Yang. (2016) Non-enzymatic acetylcholine electrochemical biosensor based on flower-like NiAl layered double hydroxides decorated with carbon dots. SENSORS AND ACTUATORS B-CHEMICAL, 233 (199). [PMID:] [10.1016/j.snb.2016.04.062]

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Acetylcholine chloride - 99%, high purity , CAS No.60-31-1

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