Acetylcholine chloride - 10mM in DMSO, high purity , CAS No.60-31-1

  • 10mM in DMSO
Item Number
A425009
Grouped product items
SKUSizeAvailabilityPrice Qty
A425009-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Endogenous neurotransmitter active at acetylcholine receptors

Basic Description

SynonymsACETYLCHOLINE CHLORIDE | 60-31-1 | Miochol | Acecoline | Acecholin | ACH chloride | Chloroacetylcholine | Arterocoline | Ovisot | Azetylcholinchlorid | 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride | MIOCHOL-E | Acetylcholinium chloride | O-Acetylcholine chloride | 2-Acetoxyeth
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsEndogenous neurotransmitter in both the central and peripheral nervous systems. Displays activity at the nicotinic and muscarinic acetylcholine receptors. Also implicated in numerous non-neuronal roles.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TRPC4 Tchem Short transient receptor potential channel 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TNNC1 Tclin Troponin C, slow skeletal and cardiac muscles (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC5A7 Tchem High affinity choline transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TARDBP Tchem TAR DNA-binding protein 43 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC5A7 Tchem High-affinity choline transporter (1462 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNNC1 Tclin Troponin, cardiac muscle (276 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trpc4 Short transient receptor potential channel 4 (1615 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
vpr Aberrant vpr protein (14595 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-acetyloxyethyl(trimethyl)azanium;chloride
INCHI InChI=1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChi Key JUGOREOARAHOCO-UHFFFAOYSA-M
Canonical SMILES CC(=O)OCC[N+](C)(C)C.[Cl-]
Isomeric SMILES CC(=O)OCC[N+](C)(C)C.[Cl-]
WGK Germany 2
RTECS FZ9800000
PubChem CID 6060
Molecular Weight 181.66
Beilstein 3571875
Reaxy-Rn 3571875

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SensitivityLight and moisture sensitive
Melt Point(°C)149-152°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS FZ9800000
Reaxy-Rn 3571875
Merck Index 87

Related Documents

Citations of This Product

1. Li Qiwei, Chen Zaozao, Zhang Ying, Ding Shuang, Ding Haibo, Wang Luping, Xie Zhuoying, Fu Yifu, Wei Mengxiao, Liu Shengnan, Chen Jialun, Wang Xuan, Gu Zhongze.  (2023)  Imaging cellular forces with photonic crystals.  Nature Communications,  14  (1): (1-14).  [PMID:37963911] [10.1038/s41467-023-43090-9]
2. Guorui Chang, Sirui Li, Yunqi Wang, Qingxia Ran, Qing Tan, Shuli Gou, Haiying Du, Shuxia Xu.  (2024)  Cu-C3N4 nanoenzyme-based freezing-dried bioactive capsule integrated with 3D-printed smartphone platform for visual detection of organophosphorus pesticides paraoxon in scallion.  SENSORS AND ACTUATORS B-CHEMICAL,  398  (1): (134584).  [PMID:17505538] [10.1016/j.snb.2023.134584]
3. Zhe Ling, Yang Tan, Xinjian Li, Ying Xie, Peng Wang, Yan Su, Qiang Yong.  (2023)  Elucidating multi-scale deconstruction of bamboo crystalline cellulose by novel acetylcholine chloride based deep eutectic solvents for enhanced enzymatic hydrolysis.  INDUSTRIAL CROPS AND PRODUCTS,  203  (117156).  [PMID:] [10.1016/j.indcrop.2023.117156]
4. Yaxu Zhao, Lijun Liang, Wei Guo, Xiong Lu, Congyi Zhao, Faming Gao.  (2023)  The porous hollow cobalt-based oxides encapsulated with bimetallic PdAu Nanoparticles of electrochemical biosensor for highly sensitive pesticides detection.  NANOTECHNOLOGY,  34  (28): (285501).  [PMID:37054697] [10.1088/1361-6528/accc8f]
5. Zhou Liping, Lao Zishan, Fan Xinsheng, Hao Mengyang, Yang Yubing.  (2023)  Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,      [PMID:37073125] [10.1093/bbb/zbad039]
6. Wang Kai, Liang Yaping, Duan Manman, Che Wunan, He Lu.  (2023)  Chronic toxicity of broflanilide in Daphnia magna: changes in molting, behavior, and gene expression.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (19): (54846-54856).  [PMID:36881221] [10.1007/s11356-023-26255-3]
7. Haoge Cheng, Kaiyue Yang, Yuze Zhang, Shenglong Liao, Menghao Du, Jiaqi Li, Ning Ma, Mianqi Xue, Xinyue Zhang, Yapei Wang.  (2022)  A Novel Ionic Conductive Polyurethane Based on Deep Eutectic Solvent Continuing Traditional Merits.  ACS Applied Materials & Interfaces,  14  (46): (52402–52410).  [PMID:36256442] [10.1021/acsami.2c15356]
8. Hangjing Zhang, Tianyuan Gao, Lei Jiang, Xiangqi Meng, Jian Wang, Ning Ma, Hao Wei, Xinyue Zhang.  (2022)  Conductive and transparent poly (N-isopropylacrylamide) hydrogels with tunable LCST copolymerized by the green acrylamide-based deep eutectic solvent.  EUROPEAN POLYMER JOURNAL,  173  (111266).  [PMID:] [10.1016/j.eurpolymj.2022.111266]
9. Zhiang Zhang, Jikun Jiang, Xiao (Xiao) Liu, Xin Wang, Luyao Wang, Yuankun Qiu, Zhanfei Zhang, Yiting Zheng, Xueyun Wu, Jianghu Liang, Congcong Tian, Chun-Chao Chen.  (2021)  Surface-Anchored Acetylcholine Regulates Band-Edge States and Suppresses Ion Migration in a 21%-Efficient Quadruple-Cation Perovskite Solar Cell.  Small,  18  (6): (2105184).  [PMID:34851037] [10.1002/smll.202105184]
10. Xinyue Dai, Kai Le, Fenglong Wang, Rubin Wei, Jiurong Liu, Yanyan Jiang, Hui Li.  (2020)  Single-Molecule Detection of Acetylcholine by Translating the Neuronal Signal to a Single Distinct Electronic Peak.  ACS Applied Bio Materials,  (10): (6888–6896).  [PMID:35019350] [10.1021/acsabm.0c00797]
11. Zhijiao Tang, Zhengyi Chen, Gongke Li, Yuling Hu.  (2020)  Multicolor nitrogen dots for rapid detection of thiram and chlorpyrifos in fruit and vegetable samples.  ANALYTICA CHIMICA ACTA,  1136  (72).  [PMID:33081951] [10.1016/j.aca.2020.08.038]
12. Benhong Xu, Huixing Deng, Xiaojing Zhang, Jingxiong Luo, Gaoxiao Zhang, Zaijun Zhang, Yuqiang Wang, Luchen Shan.  (2018)  A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs.  EUROPEAN JOURNAL OF PHARMACOLOGY,  818  (158).  [PMID:29066416] [10.1016/j.ejphar.2017.10.034]
13. Lve Wang, Xu Chen, Changxia Liu, Wensheng Yang.  (2016)  Non-enzymatic acetylcholine electrochemical biosensor based on flower-like NiAl layered double hydroxides decorated with carbon dots.  SENSORS AND ACTUATORS B-CHEMICAL,  233  (199).  [PMID:] [10.1016/j.snb.2016.04.062]

References

1. Li Qiwei, Chen Zaozao, Zhang Ying, Ding Shuang, Ding Haibo, Wang Luping, Xie Zhuoying, Fu Yifu, Wei Mengxiao, Liu Shengnan, Chen Jialun, Wang Xuan, Gu Zhongze.  (2023)  Imaging cellular forces with photonic crystals.  Nature Communications,  14  (1): (1-14).  [PMID:37963911] [10.1038/s41467-023-43090-9]
2. Guorui Chang, Sirui Li, Yunqi Wang, Qingxia Ran, Qing Tan, Shuli Gou, Haiying Du, Shuxia Xu.  (2024)  Cu-C3N4 nanoenzyme-based freezing-dried bioactive capsule integrated with 3D-printed smartphone platform for visual detection of organophosphorus pesticides paraoxon in scallion.  SENSORS AND ACTUATORS B-CHEMICAL,  398  (1): (134584).  [PMID:17505538] [10.1016/j.snb.2023.134584]
3. Zhe Ling, Yang Tan, Xinjian Li, Ying Xie, Peng Wang, Yan Su, Qiang Yong.  (2023)  Elucidating multi-scale deconstruction of bamboo crystalline cellulose by novel acetylcholine chloride based deep eutectic solvents for enhanced enzymatic hydrolysis.  INDUSTRIAL CROPS AND PRODUCTS,  203  (117156).  [PMID:] [10.1016/j.indcrop.2023.117156]
4. Yaxu Zhao, Lijun Liang, Wei Guo, Xiong Lu, Congyi Zhao, Faming Gao.  (2023)  The porous hollow cobalt-based oxides encapsulated with bimetallic PdAu Nanoparticles of electrochemical biosensor for highly sensitive pesticides detection.  NANOTECHNOLOGY,  34  (28): (285501).  [PMID:37054697] [10.1088/1361-6528/accc8f]
5. Zhou Liping, Lao Zishan, Fan Xinsheng, Hao Mengyang, Yang Yubing.  (2023)  Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,      [PMID:37073125] [10.1093/bbb/zbad039]
6. Wang Kai, Liang Yaping, Duan Manman, Che Wunan, He Lu.  (2023)  Chronic toxicity of broflanilide in Daphnia magna: changes in molting, behavior, and gene expression.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (19): (54846-54856).  [PMID:36881221] [10.1007/s11356-023-26255-3]
7. Haoge Cheng, Kaiyue Yang, Yuze Zhang, Shenglong Liao, Menghao Du, Jiaqi Li, Ning Ma, Mianqi Xue, Xinyue Zhang, Yapei Wang.  (2022)  A Novel Ionic Conductive Polyurethane Based on Deep Eutectic Solvent Continuing Traditional Merits.  ACS Applied Materials & Interfaces,  14  (46): (52402–52410).  [PMID:36256442] [10.1021/acsami.2c15356]
8. Hangjing Zhang, Tianyuan Gao, Lei Jiang, Xiangqi Meng, Jian Wang, Ning Ma, Hao Wei, Xinyue Zhang.  (2022)  Conductive and transparent poly (N-isopropylacrylamide) hydrogels with tunable LCST copolymerized by the green acrylamide-based deep eutectic solvent.  EUROPEAN POLYMER JOURNAL,  173  (111266).  [PMID:] [10.1016/j.eurpolymj.2022.111266]
9. Zhiang Zhang, Jikun Jiang, Xiao (Xiao) Liu, Xin Wang, Luyao Wang, Yuankun Qiu, Zhanfei Zhang, Yiting Zheng, Xueyun Wu, Jianghu Liang, Congcong Tian, Chun-Chao Chen.  (2021)  Surface-Anchored Acetylcholine Regulates Band-Edge States and Suppresses Ion Migration in a 21%-Efficient Quadruple-Cation Perovskite Solar Cell.  Small,  18  (6): (2105184).  [PMID:34851037] [10.1002/smll.202105184]
10. Xinyue Dai, Kai Le, Fenglong Wang, Rubin Wei, Jiurong Liu, Yanyan Jiang, Hui Li.  (2020)  Single-Molecule Detection of Acetylcholine by Translating the Neuronal Signal to a Single Distinct Electronic Peak.  ACS Applied Bio Materials,  (10): (6888–6896).  [PMID:35019350] [10.1021/acsabm.0c00797]
11. Zhijiao Tang, Zhengyi Chen, Gongke Li, Yuling Hu.  (2020)  Multicolor nitrogen dots for rapid detection of thiram and chlorpyrifos in fruit and vegetable samples.  ANALYTICA CHIMICA ACTA,  1136  (72).  [PMID:33081951] [10.1016/j.aca.2020.08.038]
12. Benhong Xu, Huixing Deng, Xiaojing Zhang, Jingxiong Luo, Gaoxiao Zhang, Zaijun Zhang, Yuqiang Wang, Luchen Shan.  (2018)  A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs.  EUROPEAN JOURNAL OF PHARMACOLOGY,  818  (158).  [PMID:29066416] [10.1016/j.ejphar.2017.10.034]
13. Lve Wang, Xu Chen, Changxia Liu, Wensheng Yang.  (2016)  Non-enzymatic acetylcholine electrochemical biosensor based on flower-like NiAl layered double hydroxides decorated with carbon dots.  SENSORS AND ACTUATORS B-CHEMICAL,  233  (199).  [PMID:] [10.1016/j.snb.2016.04.062]

Solution Calculators