Acetylsalicylic acid - 99%, high purity , Cyclooxygenase inhibitor, CAS No.50-78-2, Cyclooxygenase inhibitor

43 Citations
Item Number
A104180
Grouped product items
SKUSizeAvailabilityPrice Qty
A104180-25g
25g
In stock
$17.90
A104180-100g
100g
In stock
$30.90
A104180-500g
500g
In stock
$55.90

Cyclooxygenase inhibitor; NSAID

View related series
Carbonyl compound carboxylic acid

Basic Description

SynonymsASA | Acesal | Acetisal | Aspirdrops | Solpyron | A.S.A. empirin | Acetosal | Benaspir | Contrheuma retard | Acido acetilsalicilico | Bayer | Entericin | Kyselina 2-acetoxybenzoova | 8-hour Bayer | Acetylsalicylsaeure | Benzoic acid, 2-(acetyloxy)- | o-Ca
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsInhibitor of cyclooxygenase (COX)-1. Blocks the production of prostaglandins and thromboxanes. Exhibits antiplatelet and antithrombotic activities. Displays anticancer effects in some solid tumors. One of the first described NSAID drugs.
Storage TempDesiccated
Shipped InNormal
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionCyclooxygenase inhibitor
Product Description

Aspirin is an antiinflammatory compound that inhibits NFκB, cylooxygenase-1 (Cox-1), and cyclooxygenase-2 (Cox-2). NFκB is a transcription factor that plays an important role in the expression of cellular and viral genes, which regulate the inflammatory response and infection. Adhesion molecules IL-1 and IL-6 are genes regulated by NFκB. Along with sodium salicylate, aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription. Research indicates that aspirin acts at a site downstream of glutamate receptors and blocks induction of NFκB mediated by glutamate. Additional studies suggest that aspirin and sodium salicylate specifically inhibit IKKβ, which results in the blocking of NFκB genes responsible for the inflammatory response. Aspirin has also been described to elevate extracellular adenosine levels, downregulate the expression and activity of inducible NOS, decrease the levels of adenosine triphosphate, act on multiple mitogen-activated protein kinase activities, and block the uncoupling of oxidative phosphorylation. Studies reveal that aspirin alters the equilibrium of Mcl-1/Noxa, giving rise to apoptosis of leukemia cells, independent of NFκB and MAPKs.
An inhibitor of COX-1 (cylooxygenase) and NFκB.

Product Properties

ALogP1.2

Associated Targets(Human)

NAPRT Tchem Nicotinate phosphoribosyltransferase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ASIC3 Tchem Acid-sensing ion channel 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PLA2G1B Phospholipase A2 group 1B (227 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGES Prostaglandin E synthase (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gusb Beta-glucuronidase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ggt1 Gamma-glutamyltranspeptidase 1 (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pneumocystis carinii (749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meyerozyma guilliermondii (575 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptosporidium parvum (1150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nakaseomyces glabratus (9108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus sp. (1192 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhesus monkey (3147 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-12 (7051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cynomolgus monkey (4946 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488179680
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179680
IUPAC Name 2-acetyloxybenzoic acid
INCHI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChi Key BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Canonical SMILES CC(=O)OC1=CC=CC=C1C(=O)O
Isomeric SMILES CC(=O)OC1=CC=CC=C1C(=O)O
WGK Germany 1
RTECS VO0700000
PubChem CID 2244
UN Number 2811
Packing Group I
Molecular Weight 180.16
Beilstein 779271
Reaxy-Rn 779271

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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21 results found

Lot NumberCertificate TypeDateItem
G2409170Certificate of AnalysisJun 14, 2024 A104180
G2409169Certificate of AnalysisJun 14, 2024 A104180
G2409168Certificate of AnalysisJun 14, 2024 A104180
G2409166Certificate of AnalysisJun 14, 2024 A104180
F2415101Certificate of AnalysisMar 23, 2024 A104180
F2426599Certificate of AnalysisMar 23, 2024 A104180
F2426598Certificate of AnalysisMar 23, 2024 A104180
F2206103Certificate of AnalysisMar 18, 2022 A104180
K2324099Certificate of AnalysisMar 18, 2022 A104180
F2306054Certificate of AnalysisMar 18, 2022 A104180
F2206105Certificate of AnalysisMar 18, 2022 A104180
F2206102Certificate of AnalysisMar 18, 2022 A104180
F2206008Certificate of AnalysisMar 18, 2022 A104180
F2206006Certificate of AnalysisMar 18, 2022 A104180
C2413094Certificate of AnalysisMar 18, 2022 A104180
A2225059Certificate of AnalysisDec 20, 2021 A104180
B2302420Certificate of AnalysisDec 20, 2021 A104180
B2302418Certificate of AnalysisDec 20, 2021 A104180
A2225062Certificate of AnalysisDec 20, 2021 A104180
A2225061Certificate of AnalysisDec 20, 2021 A104180
A2225060Certificate of AnalysisDec 20, 2021 A104180

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 1.8, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: 18.02, Max Conc. mM: 100
SensitivityMoisture sensitive.
Flash Point(°F)446 °F
Flash Point(°C)250℃
Melt Point(°C)136-140°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 1
RTECS VO0700000
Reaxy-Rn 779271
Class 6.1
Merck Index 851

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18. Wei-Wei Feng, Ye-Gui Qian, Ting-Hai Wang, Qing-Yan Cui, Yuan-Yuan Yue, Pei Yuan, Xiao-Jun Bao.  (2023)  Impacts of support properties on the vacuum residue slurry-phase hydrocracking performance of Mo catalysts.  Petroleum Science,  20  (2575).  [PMID:]
19. Li Shaoping, Xiaowen Yundeng, Yang Yuqing, Liu Libo, Sun Yifan, Liu Ying, Yin Lulu, Chen Zhiyu.  (2023)  Osteogenic and anti-inflammatory effect of the multifunctional bionic hydrogel scaffold loaded with aspirin and nano-hydroxyapatite.  Frontiers in Bioengineering and Biotechnology,  11    [PMID:36761294]
20. Xiaolin Pan, Mengyuan Gao, Yun Wang, Yanping He, Tian Si, Yanlin Sun.  (2023)  Poly(lactic acid)-aspirin microspheres prepared via the traditional and improved solvent evaporation methods and its application performances.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (194).  [PMID:]
21. Pei Jing, Yuling Luo, Yun Chen, Jiangbing Tan, Chunyan Liao, Shiyong Zhang.  (2023)  Aspirin-Loaded Cross-Linked Lipoic Acid Nanodrug Prevents Postoperative Tumor Recurrence by Residual Cancer Cell Killing and Inflammatory Microenvironment Improvement.  BIOCONJUGATE CHEMISTRY,  34  (2): (366–376).  [PMID:36626242]
22. Pengzhao Han, Kai Hu, Yuanpeng Wang, Lixin Li, Pan Wang, Weixia Zhu, Haiyan Gong, Zhenqiang Zhang, Shusheng Zhang.  (2023)  Dispersive solid-phase extraction of non-steroidal anti-inflammatory drugs in water and urine samples using a magnetic ionic liquid hypercrosslinked polymer composite.  JOURNAL OF CHROMATOGRAPHY A,  1689  (463745).  [PMID:36586287]
23. Xiaolin Han, Nannan Wang, Wei Zhang, Xiaodong Liu, Qi Yu, Juying Lei, Lei Zhou, Guangli Xiu.  (2023)  Ascorbic acid promoted sulfamethoxazole degradation in MIL-88B(Fe)/H2O2 Fenton-like system.  Journal of Environmental Chemical Engineering,  11  (109144).  [PMID:]
24. Hao-Ze Li, Cheng Yang, Hai-Long Qian, Xiu-Ping Yan.  (2023)  Room-temperature synthesis of ionic covalent organic frameworks for efficient removal of diclofenac sodium from aqueous solution.  SEPARATION AND PURIFICATION TECHNOLOGY,  306  (122704).  [PMID:]
25. Haiying Gao, Hui Yu, Jun Yu, Tianhui Xu, Yiming Feng, Yan Wang, Jun Qian, Chaoqun Tan.  (2023)  The key role of crystal boron in enhanced degradation of refractory contaminants using heterogeneous Fe3+/SPC system.  CHEMOSPHERE,  311  (137131).  [PMID:36336018]
26. Shuqiong Liu, Zhenyi Xu, Jiapeng Hu, Zhenzeng Wu, Yuying Zheng.  (2022)  Preparation and sustained-release properties of poly(lactic acid)/graphene oxide porous biomimetic composite scaffolds loaded with salvianolic acid B.  RSC Advances,  12  (45): (28867-28877).  [PMID:36329763]
27. Jing Guo, Jian-Kai Tang, Bai-Fang Wang, Wen-Rui Yan, Ting Li, Xue-Jian Guo, Lei Zhang, Tao Wang, Qian-Yun Sun, Li-Wei Zhang.  (2022)  Phillygenin from Forsythia suspensa leaves exhibits analgesic potential and anti-inflammatory activity in carrageenan-induced paw edema in mice.  JOURNAL OF FOOD BIOCHEMISTRY,  46  (12): (e14460).  [PMID:36200742]
28. Chaoqun Tan, Wangqi Yu, Hong Mei, Kaiyang Chen, Tianhui Xu, Huiming Xiang, Yiming Feng, Lin Deng.  (2022)  Simultaneous removal of nitrobenzene, benzoic acid, flunixin meglumine and aspirin by CaO2/Fe(III) system: Enhanced degradation by crystal boron.  SEPARATION AND PURIFICATION TECHNOLOGY,  303  (122280).  [PMID:]
29. Guo-Qi Zhang, Wei-Wu, Yu-Han Shi, Yang Zhao, Zhi-Hong Xu.  (2023)  Flow injection spectrophotometric determination total antioxidant capacity in human serum samples based on response surface methodology to optimize synthesized peroxidase-like activity carbon dots.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  284  (121832).  [PMID:36088741]
30. Peilin Zhang, Shiru He, Siqi Wu, Yi Li, Huiying Wang, Changyang Yan, Hua Yang, Ping Li.  (2022)  Discovering a Multi-Component Combination against Vascular Dementia from Danshen-Honghua Herbal Pair by Spectrum-Effect Relationship Analysis.  Pharmaceuticals,  15  (9): (1073).  [PMID:36145294]
31. Guanghui Ren, Yan Ma, Xingjie Wang, Zhaodi Zheng, Guorong Li.  (2022)  Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation.  EUROPEAN JOURNAL OF PHARMACOLOGY,  932  (175208).  [PMID:35981603]
32. Shuwei Cai, Xian Li, Shijie Pu, Xinyu Ma, Xianru He.  (2023)  Preparation of poly(acrylamide-co-Acrylonitrile) thermosensitivity microgel and control release of aspirin.  International Journal of Polymeric Materials and Polymeric Biomaterials,  72  (14): (1142-1150).  [PMID:]
33. Xianming Zhang, Qinghua Yu, Ping Zhou, Shiyu Yang, Jiashan Xia, Tao Deng, Chao Yu.  (2022)  Blood-brain barrier penetrating carbon dots with intrinsic anti-inflammatory and drug-loading properties.  Biomaterials Advances,  139  (212995).  [PMID:35882144]
34. Fangwei Yang, Cheng Wang, Hang Yu, Yahui Guo, Yuliang Cheng, Weirong Yao, Yunfei Xie.  (2022)  Establishment of the thin-layer chromatography-surface-enhanced Raman spectroscopy and chemometrics method for simultaneous identification of eleven illegal drugs in anti-rheumatic health food.  Food Bioscience,  49  (101842).  [PMID:]
35. Yingfei Wang, Junhui Zhou, Fengliang Wang, Yi Xie, Shengwei Liu, Zhimin Ao, Chuanhao Li.  (2022)  Hydrogen generation from photocatalytic treatment of wastewater containing pharmaceuticals and personal care products by Oxygen-doped crystalline carbon nitride.  SEPARATION AND PURIFICATION TECHNOLOGY,  296  (121425).  [PMID:]
36. Wang Yulin, Li Yangyang, Luo Yiling, Zhou Kailian, Qiu Xiuzhen, Guo Huishi.  (2022)  A novel molecularly imprinted polymer material for the recognition of ochratoxin A.  JOURNAL OF POLYMER RESEARCH,  29  (5): (1-11).  [PMID:]
37. Wu Yusheng, Qin Dongmiao, Meng Shuo, Zhang Chuqing, Deng Biyang.  (2022)  Carbon quantum dots with blue/near infrared emissions for ratiometric fluorescent lornoxicam sensing and bio-imaging.  MICROCHIMICA ACTA,  189  (4): (1-11).  [PMID:35347472]
38. Wu Yue, Li Kuangyu, Zeng Maolin, Qiao Boyang, Zhou Benhong.  (2022)  Serum Metabolomics Analysis of the Anti-Inflammatory Effects of Gallic Acid on Rats With Acute Inflammation.  Frontiers in Pharmacology,  13    [PMID:35392557]
39. Lan Zhenwei, Zhang Ying, Sun Yue, Wang Lvhong, Huang Yuting, Cao Hui, Wang Shumei, Meng Jiang.  (2021)  Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS.  Frontiers in Pharmacology,  12    [PMID:34955839]
40. Li-Hua Liu,Cheng-Xiong Yang,Xiu-Ping Yan.  (2016-12-13)  Methacrylate-bonded covalent-organic framework monolithic columns for high performance liquid chromatography..  Journal of chromatography. A,  1479  (137-144).  [PMID:27939601]
41. Tingting Li,Bing Yang,Xuepeng Li,Jianrong Li,Guohua Zhao,Jianquan Kan.  (2018-08-02)  Quorum sensing system and influence on food spoilage in Pseudomonas fluorescens from turbot..  Journal of food science and technology,  55  ((8)): (3016-3025).  [PMID:30065411]
42. Jing Li,Li Xu,Zhi-Guo Shi.  (2018-12-12)  Waxberry-like hierarchically porous ethyl-bridged hybrid silica microsphere: A substrate for enzyme catalysis and high-performance liquid chromatography..  Journal of chromatography. A,  1587  (79-87).  [PMID:30527847]
43. Isam Karam,Ning Ma,Xi-Wang Liu,Shi-Hong Li,Xiao-Jun Kong,Jian-Yong Li,Ya-Jun Yang.  (2015-08-21)  Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia..  BMC veterinary research,  11  (217-217).  [PMID:26289078]

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20. Xiaolin Pan, Mengyuan Gao, Yun Wang, Yanping He, Tian Si, Yanlin Sun.  (2023)  Poly(lactic acid)-aspirin microspheres prepared via the traditional and improved solvent evaporation methods and its application performances.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (194).  [PMID:]
21. Pei Jing, Yuling Luo, Yun Chen, Jiangbing Tan, Chunyan Liao, Shiyong Zhang.  (2023)  Aspirin-Loaded Cross-Linked Lipoic Acid Nanodrug Prevents Postoperative Tumor Recurrence by Residual Cancer Cell Killing and Inflammatory Microenvironment Improvement.  BIOCONJUGATE CHEMISTRY,  34  (2): (366–376).  [PMID:36626242]
22. Pengzhao Han, Kai Hu, Yuanpeng Wang, Lixin Li, Pan Wang, Weixia Zhu, Haiyan Gong, Zhenqiang Zhang, Shusheng Zhang.  (2023)  Dispersive solid-phase extraction of non-steroidal anti-inflammatory drugs in water and urine samples using a magnetic ionic liquid hypercrosslinked polymer composite.  JOURNAL OF CHROMATOGRAPHY A,  1689  (463745).  [PMID:36586287]
23. Xiaolin Han, Nannan Wang, Wei Zhang, Xiaodong Liu, Qi Yu, Juying Lei, Lei Zhou, Guangli Xiu.  (2023)  Ascorbic acid promoted sulfamethoxazole degradation in MIL-88B(Fe)/H2O2 Fenton-like system.  Journal of Environmental Chemical Engineering,  11  (109144).  [PMID:]
24. Hao-Ze Li, Cheng Yang, Hai-Long Qian, Xiu-Ping Yan.  (2023)  Room-temperature synthesis of ionic covalent organic frameworks for efficient removal of diclofenac sodium from aqueous solution.  SEPARATION AND PURIFICATION TECHNOLOGY,  306  (122704).  [PMID:]
25. Haiying Gao, Hui Yu, Jun Yu, Tianhui Xu, Yiming Feng, Yan Wang, Jun Qian, Chaoqun Tan.  (2023)  The key role of crystal boron in enhanced degradation of refractory contaminants using heterogeneous Fe3+/SPC system.  CHEMOSPHERE,  311  (137131).  [PMID:36336018]
26. Shuqiong Liu, Zhenyi Xu, Jiapeng Hu, Zhenzeng Wu, Yuying Zheng.  (2022)  Preparation and sustained-release properties of poly(lactic acid)/graphene oxide porous biomimetic composite scaffolds loaded with salvianolic acid B.  RSC Advances,  12  (45): (28867-28877).  [PMID:36329763]
27. Jing Guo, Jian-Kai Tang, Bai-Fang Wang, Wen-Rui Yan, Ting Li, Xue-Jian Guo, Lei Zhang, Tao Wang, Qian-Yun Sun, Li-Wei Zhang.  (2022)  Phillygenin from Forsythia suspensa leaves exhibits analgesic potential and anti-inflammatory activity in carrageenan-induced paw edema in mice.  JOURNAL OF FOOD BIOCHEMISTRY,  46  (12): (e14460).  [PMID:36200742]
28. Chaoqun Tan, Wangqi Yu, Hong Mei, Kaiyang Chen, Tianhui Xu, Huiming Xiang, Yiming Feng, Lin Deng.  (2022)  Simultaneous removal of nitrobenzene, benzoic acid, flunixin meglumine and aspirin by CaO2/Fe(III) system: Enhanced degradation by crystal boron.  SEPARATION AND PURIFICATION TECHNOLOGY,  303  (122280).  [PMID:]
29. Guo-Qi Zhang, Wei-Wu, Yu-Han Shi, Yang Zhao, Zhi-Hong Xu.  (2023)  Flow injection spectrophotometric determination total antioxidant capacity in human serum samples based on response surface methodology to optimize synthesized peroxidase-like activity carbon dots.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  284  (121832).  [PMID:36088741]
30. Peilin Zhang, Shiru He, Siqi Wu, Yi Li, Huiying Wang, Changyang Yan, Hua Yang, Ping Li.  (2022)  Discovering a Multi-Component Combination against Vascular Dementia from Danshen-Honghua Herbal Pair by Spectrum-Effect Relationship Analysis.  Pharmaceuticals,  15  (9): (1073).  [PMID:36145294]
31. Guanghui Ren, Yan Ma, Xingjie Wang, Zhaodi Zheng, Guorong Li.  (2022)  Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation.  EUROPEAN JOURNAL OF PHARMACOLOGY,  932  (175208).  [PMID:35981603]
32. Shuwei Cai, Xian Li, Shijie Pu, Xinyu Ma, Xianru He.  (2023)  Preparation of poly(acrylamide-co-Acrylonitrile) thermosensitivity microgel and control release of aspirin.  International Journal of Polymeric Materials and Polymeric Biomaterials,  72  (14): (1142-1150).  [PMID:]
33. Xianming Zhang, Qinghua Yu, Ping Zhou, Shiyu Yang, Jiashan Xia, Tao Deng, Chao Yu.  (2022)  Blood-brain barrier penetrating carbon dots with intrinsic anti-inflammatory and drug-loading properties.  Biomaterials Advances,  139  (212995).  [PMID:35882144]
34. Fangwei Yang, Cheng Wang, Hang Yu, Yahui Guo, Yuliang Cheng, Weirong Yao, Yunfei Xie.  (2022)  Establishment of the thin-layer chromatography-surface-enhanced Raman spectroscopy and chemometrics method for simultaneous identification of eleven illegal drugs in anti-rheumatic health food.  Food Bioscience,  49  (101842).  [PMID:]
35. Yingfei Wang, Junhui Zhou, Fengliang Wang, Yi Xie, Shengwei Liu, Zhimin Ao, Chuanhao Li.  (2022)  Hydrogen generation from photocatalytic treatment of wastewater containing pharmaceuticals and personal care products by Oxygen-doped crystalline carbon nitride.  SEPARATION AND PURIFICATION TECHNOLOGY,  296  (121425).  [PMID:]
36. Wang Yulin, Li Yangyang, Luo Yiling, Zhou Kailian, Qiu Xiuzhen, Guo Huishi.  (2022)  A novel molecularly imprinted polymer material for the recognition of ochratoxin A.  JOURNAL OF POLYMER RESEARCH,  29  (5): (1-11).  [PMID:]
37. Wu Yusheng, Qin Dongmiao, Meng Shuo, Zhang Chuqing, Deng Biyang.  (2022)  Carbon quantum dots with blue/near infrared emissions for ratiometric fluorescent lornoxicam sensing and bio-imaging.  MICROCHIMICA ACTA,  189  (4): (1-11).  [PMID:35347472]
38. Wu Yue, Li Kuangyu, Zeng Maolin, Qiao Boyang, Zhou Benhong.  (2022)  Serum Metabolomics Analysis of the Anti-Inflammatory Effects of Gallic Acid on Rats With Acute Inflammation.  Frontiers in Pharmacology,  13    [PMID:35392557]
39. Lan Zhenwei, Zhang Ying, Sun Yue, Wang Lvhong, Huang Yuting, Cao Hui, Wang Shumei, Meng Jiang.  (2021)  Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS.  Frontiers in Pharmacology,  12    [PMID:34955839]
40. Li-Hua Liu,Cheng-Xiong Yang,Xiu-Ping Yan.  (2016-12-13)  Methacrylate-bonded covalent-organic framework monolithic columns for high performance liquid chromatography..  Journal of chromatography. A,  1479  (137-144).  [PMID:27939601]
41. Tingting Li,Bing Yang,Xuepeng Li,Jianrong Li,Guohua Zhao,Jianquan Kan.  (2018-08-02)  Quorum sensing system and influence on food spoilage in Pseudomonas fluorescens from turbot..  Journal of food science and technology,  55  ((8)): (3016-3025).  [PMID:30065411]
42. Jing Li,Li Xu,Zhi-Guo Shi.  (2018-12-12)  Waxberry-like hierarchically porous ethyl-bridged hybrid silica microsphere: A substrate for enzyme catalysis and high-performance liquid chromatography..  Journal of chromatography. A,  1587  (79-87).  [PMID:30527847]
43. Isam Karam,Ning Ma,Xi-Wang Liu,Shi-Hong Li,Xiao-Jun Kong,Jian-Yong Li,Ya-Jun Yang.  (2015-08-21)  Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia..  BMC veterinary research,  11  (217-217).  [PMID:26289078]

Solution Calculators