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Acipimox - ≥98%, high purity , CAS No.51037-30-0, Agonist of HCA 2 receptor
Antilipolytic agent. Nicotinic acid derivative.
Basic Description Synonyms ACIPIMOX|51037-30-0|Olbetam|5-Carboxy-2-methylpyrazine 1-oxide|Olbemox|5-methylpyrazine-2-carboxylic acid 4-oxide|5-Methylpyrazinecarboxylic acid 4-oxide|5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid|2-CARBOXY-5-METHYLPYRAZINE 4-OXIDE|K-9321|NSC-759818| Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms Antilipolytic agent. Nicotinic acid derivative. Stimulates leptin release. Increases VLDL-Tg clearance. Lowers serum triglyceride levels in vivo. Orally active. Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of HCA 2 receptor Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. Product Description Acipimox is a niacin derivative.
Names and Identifiers Pubchem Sid 488195304 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488195304 IUPAC Name 5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid INCHI InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10) InChi Key DJQOOSBJCLSSEY-UHFFFAOYSA-N Canonical SMILES CC1=CN=C(C=[N+]1[O-])C(=O)O Isomeric SMILES CC1=CN=C(C=[N+]1[O-])C(=O)O RTECS UQ2453000 PubChem CID 5310993 Molecular Weight 154.12 Beilstein 25(5)4,200 Reaxy-Rn 777471
Chemical and Physical Properties Solubility Soluble in methanol, water (100 mM), DMSO (100 mM), ethanol (<1 mg/ml at 25 °C), and 1 M NH4OH (1 mg/ml). Sensitivity Heat sensitive Melt Point(°C) 180°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H319: Causes serious eye irritation
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
RTECS UQ2453000 Reaxy-Rn 777471 Merck Index 111
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