Acitretin - 98%, high purity , Retinoid receptor agonist, CAS No.55079-83-9, Retinoid receptor agonist

Item Number

A102064

• Synonyms: Acitretin | 55079-83-9 | Etretin | Soriatane | Neotigason | Acitretine | all-trans-Acitretin | Retinoid etretin | Acitretina | Acitretinum | Ro 10-1670 | (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid | TMMP | Acitretinum [Latin] | Ro 10-1
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).Synthetic, highly lipophilic retinoid. Etretinate metabolite with a shorter half-life. Increases ADAM10 gene expression. Induce
• Storage Temp: Protected from light,Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Retinoid receptor agonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

It is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. It is also a systemic retinoid drug used in the treatment of severe psoriasis.