ACPA (Arachidonylcyclopropylamide) - ≥98%, high purity , CAS No.229021-64-1, Agonist of CB 1 receptor;Agonist of GPR18

Item Number
A274643
Grouped product items
SKUSizeAvailabilityPrice Qty
A274643-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$105.90
A274643-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$474.90

CB 1 agonist

View related series
CB1 receptor Agonist GPR18 Agonist

Basic Description

Synonymsacpa | GTPL739 | arachidonylcyclopropylamide | HMS3649N09 | Q4783530 | N-(Cyclopropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide | NCGC00162405-01 | SCHEMBL6517985 | arachidonyl cyclopropylamide | SR-01000946681-1 | BA17967 | ACPA (in Tocrisolvetrade mark 100) | S
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsPotent, selective CB 1 agonist (K i = 2.2 nM), >300-fold selective over CB 2 receptors. Active in vivo .
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of CB 1 receptor;Agonist of GPR18
NoteProviding storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C (desiccating conditions).

Associated Targets(Human)

CNR1 Tclin Cannabinoid receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GPR18 Tchem N-arachidonyl glycine receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide
INCHI InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChi Key GLGAUBPACOBAMV-DOFZRALJSA-N
Canonical SMILES CCCCCC=CCC=CCC=CCC=CCCCC(=O)NC1CC1
Isomeric SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC1CC1
Alternate CAS 229021-64-1
PubChem CID 5311007
MeSH Entry Terms ACPA cpd;arachidonylcyclopropylamide
Molecular Weight 343.55

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySupplied in ethanol (10 mg/ml)

Related Documents

Citations of This Product

1. Xuexue Feng, Tielei Wu, Bingqing Yu, Yan Wang, Shian Zhong.  (2017)  Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase.  RSC Advances,  (45): (28082-28091).  [PMID:] [10.1039/C7RA00202E]

References

1. Xuexue Feng, Tielei Wu, Bingqing Yu, Yan Wang, Shian Zhong.  (2017)  Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase.  RSC Advances,  (45): (28082-28091).  [PMID:] [10.1039/C7RA00202E]

Solution Calculators