ACT-389949 - 98%, high purity , CAS No.1258417-54-7, Agonist of FPR2/ALX

Item Number

A412452

Grouped product items
SKU	Size	Availability	Price
A412452-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$259.90
A412452-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90
A412452-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$119.90
A412452-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,035.90

ADC Cytotoxin

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Basic Description

Synonyms	N-(2-{[4-(1,1-difluoroethyl)-1,3-oxazol-2-yl]methyl}-2H-1,2,3-triazol-4-yl)-2-methyl-5-(3-methylphenyl)-1,3-oxazole-4-carboxamide \| N-[2-[[4-(1,1-difluoroethyl)-1,3-oxazol-2-yl]methyl]triazol-4-yl]-2-methyl-5-(3-methylphenyl)-1,3-oxazole-4-carboxamide \| A
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	ACT-389949 is a potent, selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX) with EC50 of 3 nM for FPR2/ALX internalization into monocytes. ACT-389949 has potential for inflammatory disorders.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of FPR2/ALX
Product Description	Information ACT-389949 is a potent, selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX) with EC50 of 3 nM for FPR2/ALX internalization into monocytes. ACT-389949 has potential for inflammatory disorders.

Names and Identifiers

IUPAC Name	N-[2-[[4-(1,1-difluoroethyl)-1,3-oxazol-2-yl]methyl]triazol-4-yl]-2-methyl-5-(3-methylphenyl)-1,3-oxazole-4-carboxamide
INCHI	InChI=1S/C20H18F2N6O3/c1-11-5-4-6-13(7-11)18-17(24-12(2)31-18)19(29)26-15-8-23-28(27-15)9-16-25-14(10-30-16)20(3,21)22/h4-8,10H,9H2,1-3H3,(H,26,27,29)
InChi Key	PBTWPEDVIMHJEO-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=CC=C1)C2=C(N=C(O2)C)C(=O)NC3=NN(N=C3)CC4=NC(=CO4)C(C)(F)F
Isomeric SMILES	CC1=CC(=CC=C1)C2=C(N=C(O2)C)C(=O)NC3=NN(N=C3)CC4=NC(=CO4)C(C)(F)F
Alternate CAS	1258417-54-7
PubChem CID	49834265
MeSH Entry Terms	2-methyl-5-m-tolyloxazole-4-carboxylic acid (2-(4-(1,1-difluoroethyl)oxazol-2-ylmethyl)-2H-(1,2,3)triazol-4-yl)amide;ACT-389949
Molecular Weight	428.4

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
A2426242	Certificate of Analysis	Dec 25, 2023	A412452
A2426243	Certificate of Analysis	Dec 25, 2023	A412452
A2426244	Certificate of Analysis	Dec 25, 2023	A412452
A2426245	Certificate of Analysis	Dec 25, 2023	A412452
A2426247	Certificate of Analysis	Dec 25, 2023	A412452

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Basic Description