| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A425722-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $160.90 |
High affinity adenine receptor agonist
| Synonyms | adenine | 73-24-5 | 1H-Purin-6-amine | 6-Aminopurine | 9H-Purin-6-amine | 7H-Purin-6-amine | Vitamin B4 | Adenin | Adeninimine | Leuco-4 | 6-Amino-1H-purine | 6-Amino-3H-purine | 6-Amino-7H-purine | 6-Amino-9H-purine | 1,6-Dihydro-6-iminopurine | 3,6-Dihydro-6-iminopurine | Purine, 6-am |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Adenine is essential for many in vivo and in vitro biochemical processes. Adenine is converted to adenosine with ribose. On phosphorylation, it forms AMP, ADP and ATP. ATP is the energy currency of the cell and is required during cellular metabolism. Aden |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Adenine is a purine nucleobase. It is part of DNA, and RNA. Adenine is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP). |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 7H-purin-6-amine |
|---|---|
| INCHI | InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10) |
| InChi Key | GFFGJBXGBJISGV-UHFFFAOYSA-N |
| Canonical SMILES | Nc1ncnc2[nH]cnc12 |
| Isomeric SMILES | C1=NC2=NC=NC(=C2N1)N |
| WGK Germany | 3 |
| RTECS | AU6125000 |
| PubChem CID | 190 |
| UN Number | 2811 |
| Molecular Weight | 135.13 |
| Beilstein | 5777 |
| Reaxy-Rn | 608603 |
Enter Lot Number to search for COA:
| Sensitivity | moisture sensitive |
|---|---|
| Melt Point(°C) | 360 °C |
| Pictogram(s) | GHS06 |
|---|---|
| Signal | Danger |
| Hazard Statements | H301:Toxic if swallowed |
| Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
| WGK Germany | 3 |
| RTECS | AU6125000 |
| Reaxy-Rn | 608603 |
| Merck Index | 152 |
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| 2. Shuanghui Lu, Xiu Chen, Yujia Chen, Yingqiong Zhang, Jun Luo, Huidi Jiang, Luo Fang, Hui Zhou. (2023) Downregulation of PDZK1 by TGF-β1 promotes renal fibrosis via inducing epithelial-mesenchymal transition of renal tubular cells. BIOCHEMICAL PHARMACOLOGY, (116015). [PMID:38158021] [10.1016/j.bcp.2023.116015] |
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| 9. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342] [10.1002/jssc.202300090] |
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| 12. Chi Zhang, Man Fang, Yuanbo Gao, Yunchao Li, Louzhen Fan, Xiaohong Li. (2023) Valence-Engineered Oxidase-Mimicking Nanozyme with Specificity for Aromatic Amine Oxidation and Identification. ANALYTICAL CHEMISTRY, 95 (28): (10713–10720). [PMID:37402320] [10.1021/acs.analchem.3c01488] |
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| 36. Lanxin Xu, Yongling Zhang, Jun Zhou, Tao Jiang. (2022) Recyclable surface enhanced Raman scattering monitoring of nucleotides and their metabolites based on Au nanoflowers modified g-C3N4 nanosheets. COLLOIDS AND SURFACES B-BIOINTERFACES, 218 (112735). [PMID:35961111] [10.1016/j.colsurfb.2022.112735] |
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| 39. Hafezeh Nabipour, Shuilai Qiu, Xin Wang, Lei Song, Yuan Hu. (2022) Adenine as an efficient adsorbent for zinc ions removal from wastewater to in situ form bio-based metal–organic frameworks: A novel approach to preparing fire-safe polymers. COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 161 (107099). [PMID:] [10.1016/j.compositesa.2022.107099] |
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