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Adenosine 5ʹ-Triphosphate, Disodium Salt (ATP) - ≥98%, high purity , CAS No.987-65-5

10 Citations
  • ≥98%
Item Number
A100880
Grouped product items
SKUSizeAvailabilityPrice Qty
A100880-1g
1g
In stock
$58.90
A100880-5g
5g
In stock
$116.90
A100880-10g
10g
In stock
$210.90
A100880-25g
25g
In stock
$473.90
A100880-100g
100g
In stock
$1,705.90
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P2 agonist

Basic Description

Synonyms987-65-5 | ATP disodium salt | Adenosine triphosphate disodium | ATP disodium | Adenosine 5'-triphosphate disodium salt | Adetide | Disodium adenosine triphosphate | Disodium ATP | Adenosine 5'-Triphosphate, disodium salt | Triphosadenine | Adetphos | Triadesin A | Disodium aden
Specifications & Purity≥98%
Biochemical and Physiological MechanismsP2 purinoceptor agonist.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Adenosine 5'-Triphosphate, disodium salt is a p2 purinergic (P2X and P2Y) agonist that increases Ca2+-activated K+ channel activity. It has been found to induce a release of prostoglandin D2 and histamine from rat peritoneal mast cells in a dose-dependent manner.

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488181904
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181904
IUPAC Name disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
INCHI InChI=1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChi Key TTWYZDPBDWHJOR-IDIVVRGQSA-L
Canonical SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.[Na+].[Na+]
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.[Na+].[Na+]
PubChem CID 13803
Molecular Weight 551.15

Certificates

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43 results found

Lot NumberCertificate TypeDateItem
G2415032Certificate of AnalysisJul 22, 2024 A100880
G2405028Certificate of AnalysisJul 22, 2024 A100880
G2415029Certificate of AnalysisJul 22, 2024 A100880
G2415030Certificate of AnalysisJul 22, 2024 A100880
G2415031Certificate of AnalysisJul 22, 2024 A100880
D2417083Certificate of AnalysisApr 27, 2024 A100880
D2417084Certificate of AnalysisApr 27, 2024 A100880
D2417085Certificate of AnalysisApr 27, 2024 A100880
D2417086Certificate of AnalysisApr 27, 2024 A100880
D2417087Certificate of AnalysisApr 27, 2024 A100880
B2427513Certificate of AnalysisMar 04, 2024 A100880
B2427514Certificate of AnalysisMar 04, 2024 A100880
B2427512Certificate of AnalysisMar 04, 2024 A100880
B2427511Certificate of AnalysisMar 04, 2024 A100880
B2427510Certificate of AnalysisMar 04, 2024 A100880
A2425181Certificate of AnalysisJan 26, 2024 A100880
A2425182Certificate of AnalysisJan 26, 2024 A100880
K2314272Certificate of AnalysisNov 20, 2023 A100880
K2314116Certificate of AnalysisNov 20, 2023 A100880
K2314587Certificate of AnalysisNov 20, 2023 A100880
H2310064Certificate of AnalysisAug 15, 2023 A100880
H2310059Certificate of AnalysisAug 15, 2023 A100880
H2310057Certificate of AnalysisAug 15, 2023 A100880
H2310055Certificate of AnalysisAug 15, 2023 A100880
H2310051Certificate of AnalysisAug 15, 2023 A100880
G2315177Certificate of AnalysisJul 22, 2023 A100880
G2315085Certificate of AnalysisJul 22, 2023 A100880
G2315196Certificate of AnalysisJul 22, 2023 A100880
G2315176Certificate of AnalysisJul 22, 2023 A100880
G2315175Certificate of AnalysisJul 22, 2023 A100880
C2304283Certificate of AnalysisMar 08, 2023 A100880
C2304282Certificate of AnalysisMar 08, 2023 A100880
C2304284Certificate of AnalysisMar 08, 2023 A100880
C2304285Certificate of AnalysisMar 07, 2023 A100880
C2304281Certificate of AnalysisMar 07, 2023 A100880
J2222112Certificate of AnalysisOct 26, 2022 A100880
J2222114Certificate of AnalysisOct 26, 2022 A100880
J2222133Certificate of AnalysisOct 26, 2022 A100880
J2212113Certificate of AnalysisOct 17, 2022 A100880
G2206099Certificate of AnalysisJul 09, 2022 A100880
G2206098Certificate of AnalysisJul 08, 2022 A100880
G2206101Certificate of AnalysisJul 08, 2022 A100880
E2225007Certificate of AnalysisMay 28, 2022 A100880

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 55.11, Max Conc. mM: 100
Melt Point(°C)188-190°C

Related Documents

 SDS

 Specification Sheet

FAQs and Articles

FAQ
Targeted drug discovery: scarce and inefficient, what is the geometry of its effectiveness?
Categories: Technical articles
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Targeted drug Drug discovery Discovery origin Target-based drug Phenotype-based drugs

Citations of This Product

1. Ting Liu, Ling Wang, Yang Yu, Zhuo Zhang, Zelong Duan, Yawen Li, Chencan Li.  (2024)  Adenosine Triphosphatase-Stabilized ZIF-67 as Peroxidase Mimic for Rapid Detection of Glutathione.  INORGANIC CHEMISTRY COMMUNICATIONS,  159  (1): (111705).  [PMID:14612514]
2. Ting Zeng, Jie Yin, Ziwen Liu, Zhaoxing Li, Yu Zhang, Yang Lv, Mei-Ling Lu, Min Luo, Meirong Chen, Yibei Xiao.  (2023)  Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system.  Cell Reports,  42  (112698).  [PMID:37379212]
3. Hong Liu, Xuliang Yang, Bo Huang, Hongxiang Liu.  (2023)  A universal approach for synthesis of copper nanoclusters templated by G-rich oligonucleotide sequences and their applications in sensing.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  297  (122740).  [PMID:37080047]
4. Minglei Tao, Shengzhi Liu, Yaohan Li, Amin Liu, Zijian Sun, Vinesh Maharaj, Shouxin Li, Jingkui Tian, Wei Zhu.  (2023)  Comprehensive multi-omics analysis reveals the importance of CtCOSY in the energy metabolism and coumarin biosynthesis in Clematis terniflora DC.  INDUSTRIAL CROPS AND PRODUCTS,  195  (116444).  [PMID:]
5. Yue Xin, Dun Zhang, Yan Zeng, Yingwen Wang, Peng Qi.  (2023)  A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate.  Analytical Methods,  15  (6): (788-796).  [PMID:36691974]
6. Yue Xin, Dun Zhang, Yan Zeng, Peng Qi.  (2023)  An abiotic carbon dots@ ZIF-90 fluorescent probe for rapid and reliable detection of adenosine triphosphate.  ANALYTICAL BIOCHEMISTRY,  663  (115021).  [PMID:36539047]
7. Jinling Xu, Qi Lv, Shumin Pan, Huanhuan Qiu, Yu Liao, Ming Zhou, Weijie Li, Caiyan Li, Pan Zhang, Yujian Li, Guanglin Xu, Qingfeng Yu.  (2022)  M378 exhibits anti-inflammatory activities through NLRP3 signaling pathway.  EUROPEAN JOURNAL OF PHARMACOLOGY,  933  (175261).  [PMID:36100126]
8. Jiulong Zhang, Xiaoyan Sun, Lin Liu, Xiufeng Zhao, Chunrong Yang, Kexin Li, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Tumor-permeated ATP-based size-controllable immunogenic cell death amplifier remodel immunosuppressive microenvironment to boost cancer immunotherapy.  Applied Materials Today,  28  (101518).  [PMID:]
9. Jiulong Zhang, Xiaoyan Sun, Xiufeng Zhao, Chunrong Yang, Menghao Shi, Benzhuo Zhang, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy.  Acta Pharmaceutica Sinica B,  12  (3694).  [PMID:36176905]
10. Jiulong Zhang, Xiaoyan Sun, Xiufeng Zhao, Lin Liu, Xin Cheng, Chunrong Yang, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Watson–Crick Base Pairing-Inspired Laser/GSH Activatable miRNA-Coordination Polymer Nanoplexes for Combined Cancer Chemo-Immuno-Photothermal Therapy.  ACS Applied Materials & Interfaces,  14  (18): (20762–20777).  [PMID:35476413]

References

1. Ting Liu, Ling Wang, Yang Yu, Zhuo Zhang, Zelong Duan, Yawen Li, Chencan Li.  (2024)  Adenosine Triphosphatase-Stabilized ZIF-67 as Peroxidase Mimic for Rapid Detection of Glutathione.  INORGANIC CHEMISTRY COMMUNICATIONS,  159  (1): (111705).  [PMID:14612514]
2. Ting Zeng, Jie Yin, Ziwen Liu, Zhaoxing Li, Yu Zhang, Yang Lv, Mei-Ling Lu, Min Luo, Meirong Chen, Yibei Xiao.  (2023)  Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system.  Cell Reports,  42  (112698).  [PMID:37379212]
3. Hong Liu, Xuliang Yang, Bo Huang, Hongxiang Liu.  (2023)  A universal approach for synthesis of copper nanoclusters templated by G-rich oligonucleotide sequences and their applications in sensing.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  297  (122740).  [PMID:37080047]
4. Minglei Tao, Shengzhi Liu, Yaohan Li, Amin Liu, Zijian Sun, Vinesh Maharaj, Shouxin Li, Jingkui Tian, Wei Zhu.  (2023)  Comprehensive multi-omics analysis reveals the importance of CtCOSY in the energy metabolism and coumarin biosynthesis in Clematis terniflora DC.  INDUSTRIAL CROPS AND PRODUCTS,  195  (116444).  [PMID:]
5. Yue Xin, Dun Zhang, Yan Zeng, Yingwen Wang, Peng Qi.  (2023)  A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate.  Analytical Methods,  15  (6): (788-796).  [PMID:36691974]
6. Yue Xin, Dun Zhang, Yan Zeng, Peng Qi.  (2023)  An abiotic carbon dots@ ZIF-90 fluorescent probe for rapid and reliable detection of adenosine triphosphate.  ANALYTICAL BIOCHEMISTRY,  663  (115021).  [PMID:36539047]
7. Jinling Xu, Qi Lv, Shumin Pan, Huanhuan Qiu, Yu Liao, Ming Zhou, Weijie Li, Caiyan Li, Pan Zhang, Yujian Li, Guanglin Xu, Qingfeng Yu.  (2022)  M378 exhibits anti-inflammatory activities through NLRP3 signaling pathway.  EUROPEAN JOURNAL OF PHARMACOLOGY,  933  (175261).  [PMID:36100126]
8. Jiulong Zhang, Xiaoyan Sun, Lin Liu, Xiufeng Zhao, Chunrong Yang, Kexin Li, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Tumor-permeated ATP-based size-controllable immunogenic cell death amplifier remodel immunosuppressive microenvironment to boost cancer immunotherapy.  Applied Materials Today,  28  (101518).  [PMID:]
9. Jiulong Zhang, Xiaoyan Sun, Xiufeng Zhao, Chunrong Yang, Menghao Shi, Benzhuo Zhang, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy.  Acta Pharmaceutica Sinica B,  12  (3694).  [PMID:36176905]
10. Jiulong Zhang, Xiaoyan Sun, Xiufeng Zhao, Lin Liu, Xin Cheng, Chunrong Yang, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao.  (2022)  Watson–Crick Base Pairing-Inspired Laser/GSH Activatable miRNA-Coordination Polymer Nanoplexes for Combined Cancer Chemo-Immuno-Photothermal Therapy.  ACS Applied Materials & Interfaces,  14  (18): (20762–20777).  [PMID:35476413]

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