Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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A129364-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
A129364-5g | 5g | In stock | $23.90 | |
A129364-10g | 10g | In stock | $42.90 | |
A129364-25g | 25g | In stock | $83.90 | |
A129364-50g | 50g | In stock | $150.90 | |
A129364-100g | 100g | In stock | $270.90 |
Non-competitive Nicotinic acetylcholine receptor (nAChR) inhibitor. Used as an antispasmodic drug.
Synonyms | NSC758234 | NSC-758234 | MLS002222150 | Prestwick_7 | 2-(Diethylamino)ethyl diphenylacetate hydrochloride | A828115 | ADIPHENINE HCL | Adiphenine hydrochloride (USAN) | 2-(diethylamino)ethyl 2,2-diphenylacetate;hydron;chloride | SCHEMBL33478 | Ethanol, 2- |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Adiphenine HCl is a nicotinic receptor inhibitor.Non-competitive Nicotinic acetylcholine receptor (nAChR) inhibitor. Used as an antispasmodic drug. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-(diethylamino)ethyl 2,2-diphenylacetate;hydrochloride |
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INCHI | InChI=1S/C20H25NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,19H,3-4,15-16H2,1-2H3;1H |
InChi Key | LKPINBXAWIMZCG-UHFFFAOYSA-N |
Canonical SMILES | CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2.Cl |
Isomeric SMILES | CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2.Cl |
WGK Germany | 3 |
RTECS | AH2625000 |
Alternate CAS | 64-95-9 |
PubChem CID | 5763 |
Molecular Weight | 347.88 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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B2327156 | Certificate of Analysis | Dec 06, 2024 | A129364 |
B2327091 | Certificate of Analysis | Dec 06, 2024 | A129364 |
B2327148 | Certificate of Analysis | Nov 12, 2022 | A129364 |
B2327149 | Certificate of Analysis | Nov 12, 2022 | A129364 |
B2327152 | Certificate of Analysis | Nov 12, 2022 | A129364 |
B2327155 | Certificate of Analysis | Nov 12, 2022 | A129364 |
B2327165 | Certificate of Analysis | Nov 12, 2022 | A129364 |
E1504056 | Certificate of Analysis | Nov 11, 2022 | A129364 |
H2204199 | Certificate of Analysis | Aug 06, 2022 | A129364 |
Solubility | DMSO 30 mg/mL Water 70 mg/mL Ethanol 18 mg/mL |
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Sensitivity | Moisture sensitive |
Melt Point(°C) | 117 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. |
WGK Germany | 3 |
RTECS | AH2625000 |
Merck Index | 161 |
Starting at $134.90
1. Jingyi Zhang, Zidan Cao, Di Fan, Yu Li, Tao Li, Baozeng Ren. (2023) Solid-liquid phase equilibrium of adiphenine hydrochloride in twelve pure solvents. JOURNAL OF CHEMICAL THERMODYNAMICS, 183 (107067). [PMID:] [10.1016/j.jct.2023.107067] |
1. Jingyi Zhang, Zidan Cao, Di Fan, Yu Li, Tao Li, Baozeng Ren. (2023) Solid-liquid phase equilibrium of adiphenine hydrochloride in twelve pure solvents. JOURNAL OF CHEMICAL THERMODYNAMICS, 183 (107067). [PMID:] [10.1016/j.jct.2023.107067] |