AdipoRon - 10mM in DMSO, high purity , CAS No.924416-43-3

  • 10mM in DMSO
Item Number
A426942
Grouped product items
SKUSizeAvailabilityPrice Qty
A426942-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$152.90

Adiponectin receptor agonist

Basic Description

SynonymsAdipoRon | 924416-43-3 | 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide | SC-396658 | ND7UVH6GKJ | CHEMBL3393145 | 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide | MFCD08271060 | 2-(4-Benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)acetamide
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsAdiponectin receptor agonist (K D values are 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively). AMPK and PPARα signaling activator. Shows antiobesogenic, antidiabetic and cardioprotective effects in vivo. Orally active.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

ADIPOR1 Tbio Adiponectin receptor protein 1 (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADIPOR2 Tbio Adiponectin receptor protein 2 (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
INCHI InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30)
InChi Key SHHUPGSHGSNPDB-UHFFFAOYSA-N
Canonical SMILES C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4
Isomeric SMILES C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4
PubChem CID 16307093
Molecular Weight 428.52

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivitylight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

Related Documents

Solution Calculators