Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A183027-25mg | 25mg | In stock | $172.90 | |
A183027-100mg | 100mg | In stock | $464.90 | |
A183027-500mg | 500mg | In stock | $1,511.90 |
Synonyms | Adriablastin | hydroxydaunomycin | Hydroxyldaunorubicin | LMPK13050001 | NCI-C01514 | Doxorubicine | NSC-759155 | D03899 | Doxorubicina [INN-Spanish] | HSDB 3070 | DOXORUBICIN (MART.) | Doxorubicinum [INN-Latin] | 14-Hydroxydaunomycin | Doxil | Probes1_00 |
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Specifications & Purity | Moligand™, ≥97% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of DNA topoisomerase II alpha |
Product Description | Adriamycin is a Topoisomerase II catalytic inhibitor, also is a broad spectrum antibiotic used in the treatment of cancers. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
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INCHI | InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 |
InChi Key | AOJJSUZBOXZQNB-TZSSRYMLSA-N |
Canonical SMILES | CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O |
Isomeric SMILES | C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O |
PubChem CID | 31703 |
Molecular Weight | 543.5 |
DrugBank Ligand | DB00997 |
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PubChem CID | 31703 |
CAS Registry No. | 23214-92-8 |
ChEMBL Ligand | CHEMBL53463 |
Wikipedia | Doxorubicin |
ChEBI | CHEBI:28748 |
RCSB PDB Ligand | DM2 |
PEP | doxorubicin |
Immunopaedia Search | doxorubicin |
DrugCentral Ligand | 960 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B23031135 | Certificate of Analysis | Jan 07, 2023 | A183027 |
B23031137 | Certificate of Analysis | Jan 07, 2023 | A183027 |
B23031140 | Certificate of Analysis | Jan 07, 2023 | A183027 |
C2404203 | Certificate of Analysis | Jan 07, 2023 | A183027 |
G2426659 | Certificate of Analysis | Jan 07, 2023 | A183027 |
G2429020 | Certificate of Analysis | Jan 07, 2023 | A183027 |
G2429082 | Certificate of Analysis | Jan 07, 2023 | A183027 |
C2215214 | Certificate of Analysis | Feb 23, 2022 | A183027 |
C2215216 | Certificate of Analysis | Feb 23, 2022 | A183027 |
C2215217 | Certificate of Analysis | Feb 23, 2022 | A183027 |
Solubility | ≥27.2 mg/mL in DMSO; insoluble in EtOH; ≥24.8 mg/mL in H2O with ultrasonic |
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Sensitivity | light & heat sensitive |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H350:May cause cancer |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |
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