Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

AEBSF Solution - 10mg/ml in H2O, high purity , CAS No.30827-99-7

7 Citations
  • 10mg/ml in H2O
Item Number
A301913
Grouped product items
SKUSizeAvailabilityPrice Qty
A301913-0.5ml
0.5ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$117.90
A301913-2×0.5ml
2×0.5ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$212.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET
View related series
Anti-infection Influenza Virus Metabolic Enzyme/Protease Ser/Thr Protease Thrombin

Basic Description

SynonymsBenzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride | DHA6VL95HL | 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride [for biochemical research] | EX-A2487 | T70748 | AKOS015847774 | Pefabloc(R) SC, certified reference material, TraceCERT(R) |
Specifications & Purity10mg/ml in H2O
Biochemical and Physiological MechanismsIrreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, impr
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLG Tclin Plasminogen (2339 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSG Tchem Cathepsin G (2304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CELA2A Pancreatic elastase (395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride
INCHI InChI=1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
InChi Key WRDABNWSWOHGMS-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
Isomeric SMILES C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
WGK Germany 3
PubChem CID 186136
UN Number 3261
Molecular Weight 239.69
Beilstein 7604627
Reaxy-Rn 7604627

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
F2110978Certificate of AnalysisMay 12, 2023 A301913

Chemical and Physical Properties

SolubilitySoluble in water 50 mg/mL or 100% ethanol.
SensitivityMoisture Sensitive
Melt Point(°C)181-185°C

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P310:Immediately call a POISON CENTER or doctor/physician.

WGK Germany 3
Reaxy-Rn 7604627

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Protease Inhibitor Cocktail
    Protease Inhibitor Cocktail
    • Animal-Free, 100×

    Starting at $265.90

  2. PMSF Solution - 100mM in ethanol, used for , CAS No. 329-98-6, by Aladdin Scientific
    PMSF Solution
    • 100mM in ethanol

    Starting at $35.90

  3. β-Glycerol phosphate disodium salt - >95.0%(T), used for , CAS No. 13408-09-8, by Aladdin Scientific
    β-Glycerol phosphate disodium salt
    • ≥95%(T)

    Starting at $29.90

  4. Ethylenediaminetetraacetic acid - 99%，for cell culture, used for , CAS No. 60-00-4, by Aladdin Scientific
    Ethylenediaminetetraacetic acid

    Starting at $19.90

  5. Pepstatin
    Pepstatin
    • ≥75%(HPLC)

    Starting at $9.90

  6. Leupeptin hemisulfate salt
    Leupeptin hemisulfate salt
    • ≥90%(HPLC)

    Starting at $22.90

  7. Bestatin - Ultra pure grade,>99%, used for , CAS No. 58970-76-6, by Aladdin Scientific
    Bestatin

    Starting at $15.90

  8. Protease Inhibitor Cocktail
    Protease Inhibitor Cocktail
    • EDTA-Free, 100×

    Starting at $774.90

  9. Sodium fluoride - for insect cell culture,≥99%, used for , CAS No. 7681-49-4, by Aladdin Scientific
    Sodium fluoride

    Starting at $40.90

  10. AEBSF Solution - 50mg/ml in H2O, used for , CAS No. 30827-99-7, by Aladdin Scientific
    AEBSF Solution
    • 50mg/ml in H2O

    Starting at $255.90

  11. Phenylmethanesulfonyl fluoride - ≥98.0% (GC), used for , CAS No. 329-98-6, by Aladdin Scientific
    Phenylmethanesulfonyl fluoride
    • ≥98%(GC)

    Starting at $12.90

  12. E-64 - protease inhibitor ,99%, used for , CAS No. 66701-25-5, by Aladdin Scientific
    E-64
    • ≥99%
    • protease inhibitor

    Starting at $58.90

  13. Sodium pyrophosphate - Analytical Reagent,99.0%, used for , CAS No. 7722-88-5, by Aladdin Scientific
    Sodium pyrophosphate
    • AR
      •
    • ≥99%

    Starting at $9.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Chenglin Li, Sifan Li, Xinsheng Li, Tao Yuan, Jialei Xu, Xixin Gu, Jianli Hua.  (2023)  A Turn-On Lipid Droplet-Targeted Near-Infrared Fluorescent Probe with a Large Stokes Shift for Detection of Intracellular Carboxylesterases and Cell Viability Imaging.  MOLECULES,  28  (5): (2317).  [PMID:36903562] [10.3390/molecules28052317]
2. Yi-Xuan Fu, Wu-Yingzheng Guo, Nan Wang, Yi-Jie Dai, Zi-Ye Zhang, Xin-Lin Sun, Wen-Chao Yang, Guang-Fu Yang.  (2022)  Diagnosis of Bacterial Plant Diseases via a Nitroreductase-Activated Fluorescent Sensor.  ANALYTICAL CHEMISTRY,  94  (50): (17692–17699).  [PMID:36469707] [10.1021/acs.analchem.2c04614]
3. Jingmin Zhang, Youmei Peng, Ying Li, Ning Wang, Yuna Chai, Chongzhen Qin, Xinru Wang, Suna Liu, Yubing Zhou, Xiaojian Zhang, Wenda Zhang.  (2022)  Development of a near-infrared fluorescent probe with large Stokes shift for carboxylesterases detection and its application in living systems.  DYES AND PIGMENTS,  198  (109993).  [PMID:] [10.1016/j.dyepig.2021.109993]
4. Yu Zhu Yang, Zi Yi Xu, Nian Bing Li, Hong Qun Luo.  (2021)  Ultrasensitive fluorescent probe for visual biosensing of esterase activity in living cells and its imaging application.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  262  (120094).  [PMID:34175764] [10.1016/j.saa.2021.120094]
5. Shuli Man, Miao Li, Jin Zhou, Haiyue Wang, Jinyan Zhang, Long Ma.  (2019)  Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-κB and TGF-β signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.  Biomaterials Science,  8  (1): (201-211).  [PMID:31664285] [10.1039/C9BM01563A]
6. Hui Zhou, Jinbao Tang, Jie Zhang, Bochao Chen, Jianfei Kan, Weifen Zhang, Jin Zhou, Huimin Ma.  (2019)  A red lysosome-targeted fluorescent probe for carboxylesterase detection and bioimaging.  Journal of Materials Chemistry B,  7  (18): (2989-2996).  [PMID:] [10.1039/C9TB00310J]
7. Juan Wang, Mengmeng Song, Chengguo Hu, Kangbing Wu.  (2018)  Portable, Self-Powered, and Light-Addressable Photoelectrochemical Sensing Platforms Using pH Meter Readouts for High-Throughput Screening of Thrombin Inhibitor Drugs.  ANALYTICAL CHEMISTRY,  90  (15): (9366–9373).  [PMID:29998727] [10.1021/acs.analchem.8b01979]

References

1. Chenglin Li, Sifan Li, Xinsheng Li, Tao Yuan, Jialei Xu, Xixin Gu, Jianli Hua.  (2023)  A Turn-On Lipid Droplet-Targeted Near-Infrared Fluorescent Probe with a Large Stokes Shift for Detection of Intracellular Carboxylesterases and Cell Viability Imaging.  MOLECULES,  28  (5): (2317).  [PMID:36903562] [10.3390/molecules28052317]
2. Yi-Xuan Fu, Wu-Yingzheng Guo, Nan Wang, Yi-Jie Dai, Zi-Ye Zhang, Xin-Lin Sun, Wen-Chao Yang, Guang-Fu Yang.  (2022)  Diagnosis of Bacterial Plant Diseases via a Nitroreductase-Activated Fluorescent Sensor.  ANALYTICAL CHEMISTRY,  94  (50): (17692–17699).  [PMID:36469707] [10.1021/acs.analchem.2c04614]
3. Jingmin Zhang, Youmei Peng, Ying Li, Ning Wang, Yuna Chai, Chongzhen Qin, Xinru Wang, Suna Liu, Yubing Zhou, Xiaojian Zhang, Wenda Zhang.  (2022)  Development of a near-infrared fluorescent probe with large Stokes shift for carboxylesterases detection and its application in living systems.  DYES AND PIGMENTS,  198  (109993).  [PMID:] [10.1016/j.dyepig.2021.109993]
4. Yu Zhu Yang, Zi Yi Xu, Nian Bing Li, Hong Qun Luo.  (2021)  Ultrasensitive fluorescent probe for visual biosensing of esterase activity in living cells and its imaging application.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  262  (120094).  [PMID:34175764] [10.1016/j.saa.2021.120094]
5. Shuli Man, Miao Li, Jin Zhou, Haiyue Wang, Jinyan Zhang, Long Ma.  (2019)  Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-κB and TGF-β signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.  Biomaterials Science,  8  (1): (201-211).  [PMID:31664285] [10.1039/C9BM01563A]
6. Hui Zhou, Jinbao Tang, Jie Zhang, Bochao Chen, Jianfei Kan, Weifen Zhang, Jin Zhou, Huimin Ma.  (2019)  A red lysosome-targeted fluorescent probe for carboxylesterase detection and bioimaging.  Journal of Materials Chemistry B,  7  (18): (2989-2996).  [PMID:] [10.1039/C9TB00310J]
7. Juan Wang, Mengmeng Song, Chengguo Hu, Kangbing Wu.  (2018)  Portable, Self-Powered, and Light-Addressable Photoelectrochemical Sensing Platforms Using pH Meter Readouts for High-Throughput Screening of Thrombin Inhibitor Drugs.  ANALYTICAL CHEMISTRY,  90  (15): (9366–9373).  [PMID:29998727] [10.1021/acs.analchem.8b01979]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.