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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A655208-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $308.90 |
Specifications & Purity | 10mM in DMSO |
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Biochemical and Physiological Mechanisms | AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC 50 value of 330 nM. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC 50 value of 330 nM. In Vivo AF38469 (1 mg/kg; i.v.) has a low volume of distribution (blood volume of 0.7 L/kg) and low clearance (4.8 L/h/kg), and a half-life (t1/2) of 1.2 h in rat . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50:330 nM (Sortilin) |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Canonical SMILES | CC1=NC(=CC=C1)NC(=O)C2=C(C=C(C=C2)C(F)(F)F)C(=O)O |
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Molecular Weight | 324.25 |
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