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AG-041R - ≥98%, high purity , CAS No.199800-49-2, Antagonist of CCK 2 receptor

  • ≥98%
Item Number
A338785
Grouped product items
SKUSizeAvailabilityPrice Qty
A338785-1mg
1mg
In stock
$68.90
A338785-5mg
5mg
In stock
$308.90

a potent CCK-BR (gastrin/CCKB receptor) antagonist that exhibits selective binding for CCKB compared to CCKA

View related series
CCK2 receptor Antagonist

Basic Description

SynonymsAG-041R|199800-49-2|159883-95-1|CID 9807431|2-[(3R)-1-(2,2-diethoxyethyl)-3-[(4-methylphenyl)carbamoylamino]-2-oxoindol-3-yl]-N-(4-methylphenyl)acetamide|LS-83786|GTPL901|MLS006010838|AG041R|AG 041R|DTXSID40430968|NCGC00263225-01|SMR004701765|J-012912|Q27
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeANTAGONIST
Mechanism of actionAntagonist of CCK 2 receptor
Product Description

The peptide hormone gastrin acts through G protein-coupled cholecystokinin-2 (CCKB) receptors to regulate cell proliferation, differentiation, apoptosis, and gene expression of gastrointestinal cells and exerts trophic effects on a number of gastric cance

Associated Targets

CCKBR Tclin Gastrin/cholecystokinin type B receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[(3R)-1-(2,2-diethoxyethyl)-3-[(4-methylphenyl)carbamoylamino]-2-oxoindol-3-yl]-N-(4-methylphenyl)acetamide
INCHI InChI=1S/C31H36N4O5/c1-5-39-28(40-6-2)20-35-26-10-8-7-9-25(26)31(29(35)37,19-27(36)32-23-15-11-21(3)12-16-23)34-30(38)33-24-17-13-22(4)14-18-24/h7-18,28H,5-6,19-20H2,1-4H3,(H,32,36)(H2,33,34,38)/t31-/m1/s1
InChi Key KOLPMNSDISYEBU-WJOKGBTCSA-N
Canonical SMILES CCOC(CN1C2=CC=CC=C2C(C1=O)(CC(=O)NC3=CC=C(C=C3)C)NC(=O)NC4=CC=C(C=C4)C)OCC
Isomeric SMILES CCOC(CN1C2=CC=CC=C2[C@@](C1=O)(CC(=O)NC3=CC=C(C=C3)C)NC(=O)NC4=CC=C(C=C4)C)OCC
Alternate CAS 199800-49-2,159883-95-1
PubChem CID 9807431
MeSH Entry Terms 3R-1-(2,2-diethoxyethyl)-3-((4-methylphenyl)aminocarbonylmethyl)-3-((4-methylphenyl)ureido)-indoline-2-one;AG-041R
Molecular Weight 544.64

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Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
K2218319Certificate of AnalysisAug 26, 2022 A338785
K2218320Certificate of AnalysisAug 26, 2022 A338785

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