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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A288315-1mg | 1mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $79.90 | |
A288315-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $478.90 | |
A288315-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $861.90 | |
A288315-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,939.90 | |
A288315-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,490.90 | |
A288315-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $6,282.90 |
Selective GnRH receptor antagonist
Synonyms | CS-0028830 | 5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide | J-016407 | NCGC00378704-01 | Furan-1 | GTPL1179 | HY-107534 | 5-[5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-NAPHTHALENYL-METHYL]-N-(2 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Kivalues are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Suppresses testosterone and luteinising hormone (LH) levelsin vivo. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR, ANTAGONIST |
Mechanism of action | Allosteric modulator of GnRH 1 receptor;Antagonist of GnRH 1 receptor |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide |
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INCHI | InChI=1S/C30H37NO5/c1-18-13-22-23(30(4,5)12-11-29(22,2)3)15-19(18)14-20-9-10-24(36-20)28(32)31-27-25(34-7)16-21(33-6)17-26(27)35-8/h9-10,13,15-17H,11-12,14H2,1-8H3,(H,31,32) |
InChi Key | IPEMCIBPDYCJLO-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC2=C(C=C1CC3=CC=C(O3)C(=O)NC4=C(C=C(C=C4OC)OC)OC)C(CCC2(C)C)(C)C |
Isomeric SMILES | CC1=CC2=C(C=C1CC3=CC=C(O3)C(=O)NC4=C(C=C(C=C4OC)OC)OC)C(CCC2(C)C)(C)C |
PubChem CID | 9957278 |
Molecular Weight | 491.62 |
PubChem CID | 9957278 |
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ChEMBL Ligand | CHEMBL494803 |
BindingDB Ligand | 50261184 |
CAS Registry No. | 263847-55-8 |
GPCRdb Ligand | CMPD-1 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2309169 | Certificate of Analysis | Oct 30, 2023 | A288315 |
K2309170 | Certificate of Analysis | Oct 30, 2023 | A288315 |
K2309171 | Certificate of Analysis | Oct 30, 2023 | A288315 |
K2309172 | Certificate of Analysis | Oct 30, 2023 | A288315 |
K2309196 | Certificate of Analysis | Oct 30, 2023 | A288315 |
K2309197 | Certificate of Analysis | Oct 30, 2023 | A288315 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 49.16, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 24.58, Max Conc. mM: 50 |
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