Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A607447-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,334.90 | |
A607447-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
A607447-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,001.90 |
Synonyms | AG17724;compound 7 |
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Specifications & Purity | Moligand™, ≥95% |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | (2R)-3-(6-fluoro-1H-benzimidazol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acid |
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INCHI | InChI=1S/C21H16FN3O3/c22-15-7-8-16-17(10-15)24-19(23-16)11-18(21(27)28)25-20(26)14-6-5-12-3-1-2-4-13(12)9-14/h1-10,18H,11H2,(H,23,24)(H,25,26)(H,27,28)/t18-/m1/s1 |
InChi Key | NKMPZFCFXCJBEY-GOSISDBHSA-N |
Canonical SMILES | C1=CC=C2C=C(C=CC2=C1)C(=O)NC(CC3=NC4=C(N3)C=C(C=C4)F)C(=O)O |
Isomeric SMILES | C1=CC=C2C=C(C=CC2=C1)C(=O)N[C@H](CC3=NC4=C(N3)C=C(C=C4)F)C(=O)O |
PubChem CID | 11675244 |
Molecular Weight | 377.37 |
RCSB PDB Ligand | 39X |
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PubChem CID | 11675244 |
ChEMBL Ligand | CHEMBL3322219 |
BindingDB Ligand | 50056214 |
CAS Registry No. | 884033-66-3 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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I2403160 | Certificate of Analysis | Jun 03, 2024 | A607447 |
I2403179 | Certificate of Analysis | Jun 03, 2024 | A607447 |
I2403182 | Certificate of Analysis | Jun 03, 2024 | A607447 |
I2403183 | Certificate of Analysis | Jun 03, 2024 | A607447 |
I2403186 | Certificate of Analysis | Jun 03, 2024 | A607447 |
Solubility | DMSO: 20 mg/mL, clear (warmed) |
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RIDADR | NONHforallmodesoftransport |
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1. Guo C, Hou X, Dong L, Marakovits J, Greasley S, Dagostino E, Ferre R, Johnson MC, Humphries PS, Li H et al.. (2014) Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.. Bioorg Med Chem Lett, 24 (17): (4187-91). [PMID:25091930] |