AG-17724 - ≥95%, high purity , CAS No.884033-66-3, Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

Item Number
A607447
Grouped product items
SKUSizeAvailabilityPrice Qty
A607447-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
A607447-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
A607447-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,001.90

Basic Description

SynonymsAG17724;compound 7
Specifications & PurityMoligand™, ≥95%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

Associated Targets(Human)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R)-3-(6-fluoro-1H-benzimidazol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acid
INCHI InChI=1S/C21H16FN3O3/c22-15-7-8-16-17(10-15)24-19(23-16)11-18(21(27)28)25-20(26)14-6-5-12-3-1-2-4-13(12)9-14/h1-10,18H,11H2,(H,23,24)(H,25,26)(H,27,28)/t18-/m1/s1
InChi Key NKMPZFCFXCJBEY-GOSISDBHSA-N
Canonical SMILES C1=CC=C2C=C(C=CC2=C1)C(=O)NC(CC3=NC4=C(N3)C=C(C=C4)F)C(=O)O
Isomeric SMILES C1=CC=C2C=C(C=CC2=C1)C(=O)N[C@H](CC3=NC4=C(N3)C=C(C=C4)F)C(=O)O
PubChem CID 11675244
Molecular Weight 377.37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
I2403160Certificate of AnalysisJun 03, 2024 A607447
I2403179Certificate of AnalysisJun 03, 2024 A607447
I2403182Certificate of AnalysisJun 03, 2024 A607447
I2403183Certificate of AnalysisJun 03, 2024 A607447
I2403186Certificate of AnalysisJun 03, 2024 A607447

Chemical and Physical Properties

SolubilityDMSO: 20 mg/mL, clear (warmed)

Safety and Hazards(GHS)

RIDADR NONHforallmodesoftransport

Related Documents

References

1. Guo C, Hou X, Dong L, Marakovits J, Greasley S, Dagostino E, Ferre R, Johnson MC, Humphries PS, Li H et al..  (2014)  Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket..  Bioorg Med Chem Lett,  24  (17): (4187-91).  [PMID:25091930]

Solution Calculators