AG 555 (Tyrphostin B46) - ≥98%, high purity , CAS No.133550-34-2

Item Number

A275199

• Synonyms: NCGC00016028-05 | Tyrphostin deriv. 46 | J-006402 | 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-,(2E)- | s6525 | KBio3_000609 | HMS3678I05 | HMS3414I05 | TYRPHOSTIN AG 555 | NCGC00015372-02 | NCGC00016028-08 | BDBM4303 | HMS2230N06 |
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Potent EGFR-tyrosine kinase inhibitor (IC 50 = 700 nM). Blocks Cdk2 activation. Active form of tyrphostin A1 . Induces cell arrest at late G1 phase (IC 50 values are 6.4 and 9.4 μM for HPV16-immortalized and normal keratinocytes respectively).
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at +4°C. The product can be stored for up to 12 months.