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Alda 1 - 10mM in DMSO, high purity , CAS No.349438-38-6
ALDH2 activator; cardioprotective
Basic Description Synonyms Alda-1 | Alda 1 | 349438-38-6 | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | N-(benzo[d][1,3]dioxol-5-ylmethyl)-2,6-dichlorobenzamide | CHEMBL465952 | Alda1 | BXB | ALDH2 Agonist, Alda-1 | Oprea1_166989 | MLS001206840 | SCHEMBL503808 | N-Benzo[1,3]dioxol-5-ylmethyl-2,6 Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Activator of aldehyde dehydrogenase 2 (ALDH2). Increases activity of wild-type ALDH2*1 and variant ALDH2*2 (by ~2-fold and 11-fold respectively). Capable of partly restoring mutant ALDH2*2 activity; protective against cardiac ischemia. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide INCHI InChI=1S/C15H11Cl2NO3/c16-10-2-1-3-11(17)14(10)15(19)18-7-9-4-5-12-13(6-9)21-8-20-12/h1-6H,7-8H2,(H,18,19) InChi Key NMKJFZCBCIUYHI-UHFFFAOYSA-N Canonical SMILES C1OC2=C(O1)C=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl Isomeric SMILES C1OC2=C(O1)C=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl WGK Germany 3 PubChem CID 831629 Molecular Weight 324.16
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS09 Signal Danger Hazard Statements H301: Toxic if swallowed
H400: Very toxic to aquatic life
Precautionary Statements P273: Avoid release to the environment.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P391: Collect spillage.
P330: Rinse mouth.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
WGK Germany 3 RIDADR UN28116.1/PGIII
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